Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sylvie Choblet"'
Autor:
Irene Cattaneo, Sylvie Choblet, Rut Valgardsdottir, Muriel Roth, Annamaria Massafra, Marten Beeg, Marco Gobbi, Martine Duonor-Cerutti, Josée Golay
Publikováno v:
Antibodies, Vol 13, Iss 1, p 15 (2024)
We designed, produced, and purified a novel IgG1-like, bispecific antibody (bsAb) directed against B-cell maturation antigen (BCMA), expressed by multiple myeloma (MM) cells, and an immune checkpoint inhibitor (ICI), PDL1, expressed in the MM microen
Externí odkaz:
https://doaj.org/article/6fa362dcbed34f4f9ee34e7988391880
Autor:
Emilia Rabia, Véronique Garambois, Christine Dhommée, Christel Larbouret, Laurie Lajoie, Yoan Buscail, Gabriel Jimenez-Dominguez, Sylvie Choblet-Thery, Emmanuelle Liaudet-Coopman, Martine Cerutti, Marta Jarlier, Patrice Ravel, Laurent Gros, Nelly Pirot, Gilles Thibault, Eugene A. Zhukovsky, Pierre-Emmanuel Gérard, André Pèlegrin, Jacques Colinge, Thierry Chardès
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The ErbB family of receptor tyrosine kinases is a primary target for small molecules and antibodies for pancreatic cancer treatment. Nonetheless, the current treatments for this tumor are not optimal due to lack of efficacy, resistance, or toxicity.
Externí odkaz:
https://doaj.org/article/8a10b603d78a414f85898e71f788257b
Derivation and Preclinical Characterization of CYT-303, a Novel NKp46-NK Cell Engager Targeting GPC3
Autor:
Antonio Arulanandam, Liang Lin, Hao-Ming Chang, Martine Cerutti, Sylvie Choblet, Peng Gao, Armin Rath, Armand Bensussan, Jean Kadouche, Daniel Teper, Ofer Mandelboim, Wei Li
Publikováno v:
Cells, Vol 12, Iss 7, p 996 (2023)
Glypican-3 (GPC3) is an oncofetal antigen that is highly expressed in multiple solid tumors, including hepatocellular carcinoma, and is barely expressed in adult normal tissues except the placenta. NKp46 activation receptor is expressed in all-natura
Externí odkaz:
https://doaj.org/article/7343882adad340089e22ccaa950edada
Autor:
Muriel Roth, Josée Golay, Rut Valgardsdottir, Rachele Alzani, Sabrina Cribioli, Antonella Interdonato, Mirco Sana, Martine Duonor-Cérutti, Sylvie Choblet
Publikováno v:
Cytotherapy. 24:161-171
Background aims The authors describe here a novel therapeutic strategy combining a bispecific antibody (bsAb) with cytokine-induced killer (CIK) cells. Methods The authors have designed, produced and purified a novel tetravalent IgG1-like CD20 × CD5
Autor:
Annick Ozil, Pierre Cérutti, Christian Berthou, Martine Pugnière, Josée Golay, Vincent Zoete, Martine Duonor-Cérutti, Olivier Michielin, Greta Ubiali, Justyna Iwaszkiewicz, Séverine Loisel, Jean Kadouche, Sylvie Choblet, Jean-Pierre Mach
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2016, 196, pp.3199--3211. ⟨10.4049/jimmunol.1501592⟩
Journal of Immunology, 2016, 196, pp.3199--3211. ⟨10.4049/jimmunol.1501592⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2016, 196, pp.3199--3211. ⟨10.4049/jimmunol.1501592⟩
Journal of Immunology, 2016, 196, pp.3199--3211. ⟨10.4049/jimmunol.1501592⟩
International audience; We have designed and validated a novel generic platform for production of tetravalent IgG1-like chimeric bispecific Abs. The VHCH1-hinge domains of mAb2 are fused through a peptidic linker to the N terminus of mAb1 H chain, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c2419f9509e5e2e99c22ecff36771a
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01392208
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01392208
Autor:
Sylvie, Juliant, Marylêne, Lévêque, Pierre, Cérutti, Annick, Ozil, Sylvie, Choblet, Marie-Luce, Violet, Marie-Christine, Slomianny, Anne, Harduin-Lepers, Martine, Cérutti
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 988
Nowadays, recombinant proteins are used with great success for the treatment of a variety of medical conditions, such as cancer, autoimmune, and infectious diseases. Several expression systems have been developed to produce human proteins, but one of
Autor:
Annick Ozil, Marie-Christine Slomianny, Sylvie Juliant, Martine Cerutti, Marie-Luce Violet, Pierre Cérutti, Anne Harduin-Lepers, Marylène Lévêque, Sylvie Choblet
Publikováno v:
Methods in Molecular Biology
Methods in Molecular Biology, 988, pp.59-77, 2012
Methods in Molecular Biology ISBN: 9781627033268
Methods in Molecular Biology, 988, pp.59-77, 2012
Methods in Molecular Biology ISBN: 9781627033268
International audience; Nowadays, recombinant proteins are used with great success for the treatment of a variety of medical conditions, such as cancer, autoimmune, and infectious diseases. Several expression systems have been developed to produce hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55004b064babe9d507f35766bd05f140
https://hal.science/hal-01224141
https://hal.science/hal-01224141
Autor:
Sylvie Choblet, Thomas Colineau, Jean Grenier, Evelyne Lopez-Crapez, Alexandre Ho-Pun-Cheung, Daniela Zsoldos, Karen Brengel-Pesce, Philippe Cleuziat, Hafid Abaibou
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 86(3)
With the increasing availability of genetic information and its relationship to human diseases, there is a growing need in the medical diagnostic field for technologies that can proceed to the parallel genotyping of multiple markers. In this paper, w