Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sylvie Avril"'
Autor:
Loris Roncali, Séverine Marionneau-Lambot, Charlotte Roy, Romain Eychenne, Sébastien Gouard, Sylvie Avril, Nicolas Chouin, Jérémie Riou, Mathilde Allard, Audrey Rousseau, François Guérard, François Hindré, Michel Chérel, Emmanuel Garcion
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105202- (2024)
Summary: Background: Glioblastoma (GB), the most aggressive brain cancer, remains a critical clinical challenge due to its resistance to conventional treatments. Here, we introduce a locoregional targeted-α-therapy (TAT) with the rat monoclonal anti
Externí odkaz:
https://doaj.org/article/c893b207ab6f4738b36ea397dd0319b1
Autor:
Charlotte Roy, Sylvie Avril, Claire Legendre, Bénédicte Lelièvre, Honorine Vellenriter, Sébastien Boni, Jérôme Cayon, Catherine Guillet, Yannick Guilloux, Michel Chérel, François Hindré, Emmanuel Garcion
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-20 (2022)
Abstract Background Glioblastoma (GB) is the most common and most aggressive malignant brain tumor. In understanding its resistance to conventional treatments, iron metabolism and related pathways may represent a novel avenue. As for many cancer cell
Externí odkaz:
https://doaj.org/article/0a0eeb58e2be4c898b2bfd258255d312
Autor:
Delphine Séhédic, Loris Roncali, Amel Djoudi, Nela Buchtova, Sylvie Avril, Michel Chérel, Frank Boury, Franck Lacoeuille, François Hindré, Emmanuel Garcion
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
Inhibition of the PI3K/Akt/mTOR signaling pathway represents a potential issue for the treatment of cancer, including glioblastoma. As such, rapamycin that inhibits the mechanistic target of rapamycin (mTOR), the downstream effector of this signaling
Externí odkaz:
https://doaj.org/article/7c81110c7cf344ad983d8b3c79d577c7
Autor:
Clément Toullec, Jean Le Bideau, Valerie Geoffroy, Boris Halgand, Nela Buchtova, Rodolfo Molina-Peña, Emmanuel Garcion, Sylvie Avril, Laurence Sindji, Admire Dube, Frank Boury, Christine Jérôme
Publikováno v:
Polymers, Vol 13, Iss 4, p 526 (2021)
Polysaccharides have received a lot of attention in biomedical research for their high potential as scaffolds owing to their unique biological properties. Fibrillar scaffolds made of chitosan demonstrated high promise in tissue engineering, especiall
Externí odkaz:
https://doaj.org/article/8802edf638914351b7c28611bb0d13fa
Autor:
Hélène, Lajous, Raphaël, Riva, Bénédicte, Lelièvre, Clément, Tétaud, Sylvie, Avril, François, Hindré, Frank, Boury, Christine, Jérôme, Philippe, Lecomte, Emmanuel, Garcion
Publikováno v:
Biomaterials science. 6(9)
Glioblastoma is the most frequent and aggressive primary malignant tumor of the central nervous system with a gloomy prognosis. Platinum derivatives and one among them, cisplatin, exhibited promising results when locally administered into the brain o
Autor:
Clément Tétaud, Philippe Lecomte, Bénédicte Lelièvre, Christine Jérôme, Raphaël Riva, Hélène Lajous, Frank Boury, François Hindré, Emmanuel Garcion, Sylvie Avril
Publikováno v:
Biomaterials Science
Biomaterials Science, 2018, 6 (9), pp.2386-2409. ⟨10.1039/c8bm00346g⟩
Biomaterials Science, Royal Society of Chemistry (RSC), 2018, 6 (9), pp.2386-2409. ⟨10.1039/c8bm00346g⟩
Biomaterials Science, 2018, 6 (9), pp.2386-2409. ⟨10.1039/c8bm00346g⟩
Biomaterials Science, Royal Society of Chemistry (RSC), 2018, 6 (9), pp.2386-2409. ⟨10.1039/c8bm00346g⟩
International audience; Glioblastoma is the most frequent and aggressive primary malignant tumor of the central nervous system with a gloomy prognosis. Platinum derivatives and one among them, cisplatin, exhibited promising results when locally admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce9f3a6a1742bd35ea5d228a5f6c2a4
https://www.hal.inserm.fr/inserm-01959991/document
https://www.hal.inserm.fr/inserm-01959991/document
Publikováno v:
BMC Cancer
BMC Cancer, BioMed Central, 2016, 16 (1), pp.1-11. 〈http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2074-y#Bib1〉. 〈10.1186/s12885-016-2074-y〉
BMC Cancer, BioMed Central, 2016, 16 (1), pp.1-11. ⟨10.1186/s12885-016-2074-y⟩
BMC Cancer, BioMed Central, 2016, 16 (1), pp.1-11. 〈http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2074-y#Bib1〉. 〈10.1186/s12885-016-2074-y〉
BMC Cancer, BioMed Central, 2016, 16 (1), pp.1-11. ⟨10.1186/s12885-016-2074-y⟩
Background Overcoming resistance to treatment is an essential issue in many cancers including glioblastoma (GBM), the deadliest primary tumor of the central nervous system. As dependence on iron is a key feature of tumor cells, using chelators to red
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2005, 16 (4), pp.1850-1858. ⟨10.1091/mbc.E04-08-0654⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2005, 16 (4), pp.1850-1858. ⟨10.1091/mbc.E04-08-0654⟩
International audience; Besides its function as a cell cycle regulator, cyclin D1 interacts with transcription factors to regulate gene activation. In this study, we show that cyclin D1 is recruited to the p21waf1 promoter by a STAT3-NcoA complex. Th
Autor:
Olivier Coqueret, Sandrine Giraud, Sylvie Avril, Hugues Gascan, David M. Heery, Frédéric Bienvenu
Publikováno v:
Journal of Biological Chemistry. 277:8004-8011
Signal transducer and activator of transcription 3 (STAT3) transcription factors are cytoplasmic proteins that induce gene activation in response to cytokine receptor stimulation. Following tyrosine phosphorylation, STAT3 proteins dimerize, transloca
Publikováno v:
International Journal of Pharmaceutics
International Journal of Pharmaceutics, 2013, 454 (2), pp.765-74. ⟨10.1016/j.ijpharm.2013.05.049⟩
International Journal of Pharmaceutics, 2013, 454 (2), pp.765-74. ⟨10.1016/j.ijpharm.2013.05.049⟩
International audience; The recent discovery of microRNA (miRNA) as major post-transcriptional repressors prompt the interest of developing novel approaches to target miRNA pathways to improve therapy. In this context, although the most significant b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea77c94931f035b388d66f5f7158b1c
https://hal.univ-angers.fr/hal-03180816
https://hal.univ-angers.fr/hal-03180816