Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Sylvie, Marleau"'
Autor:
Yosdel Soto, Arletty Hernández, Roger Sarduy, Victor Brito, Sylvie Marleau, Donna F. Vine, Ana M. Vázquez, Spencer D. Proctor
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)
BACKGROUND Atherosclerosis is triggered by the retention of apolipoprotein B‐containing lipoproteins by proteoglycans. In addition to low‐density lipoprotein, remnant lipoproteins have emerged as pivotal contributors to this pathology, particular
Externí odkaz:
https://doaj.org/article/147a6c64e1db4b59a226b05fff62ba7e
Autor:
Jade Gauvin, David N. Huynh, Isabelle Dubuc, Catherine Lê, Rafaela Tugores, Nicolas Flamand, Louis Flamand, William D. Lubell, Huy Ong, Sylvie Marleau
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The scientific and medical community faced an unprecedented global health hazard that led to nearly 7 million deaths attributable to the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In spite of the developme
Externí odkaz:
https://doaj.org/article/d8ca08f8ad2340e48c5400adb8f2cd07
Autor:
Jade Gauvin, Geneviève Frégeau, Hanan Elimam, Liliane Ménard, David Huynh, Catherine Lê, Ahsanullah Ahsanullah, William D. Lubell, Huy Ong, Sylvie Marleau
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Atherosclerosis is a chronic inflammatory disease of the arterial walls that develops at predisposed sites. As a major risk factor for adverse cardiovascular pathology, atherosclerosis can progress to myocardial infarction and stroke, due to the rupt
Externí odkaz:
https://doaj.org/article/6ed0bdd7f8a046f3a8fcaddfcabcd5a1
Publikováno v:
Journal of Controlled Release. 358:636-653
Autor:
Lesly Carolina Penaloza Arias, David N. Huynh, Samuel Babity, Sylvie Marleau, Davide Brambilla
Publikováno v:
Molecular Pharmaceutics. 19:1906-1916
Drug delivery systems such as liposomes are widely used to stabilize and increase the plasma half-life of therapeutics. In this article, we have investigated two strategies to increase the half-life of deoxyribonuclease I, an FDA-approved enzyme used
Autor:
Soudeh F. Tehrani, Jean-Michel Rabanel, Samuel Legeay, Jérôme Cayon, Jérémie Riou, Patrick Saulnier, Sylvie Marleau, V. Gaëlle Roullin, Patrice Hildgen, Guillaume Bastiat
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, In press, ⟨10.1016/j.ejpb.2022.04.003⟩
European Journal of Pharmaceutics and Biopharmaceutics, In press, ⟨10.1016/j.ejpb.2022.04.003⟩
International audience; Polymer nanoparticles (NPs) are extensively studied as drug delivery systems for various therapeutic indications, including drug and imaging agent delivery to the brain. Despite intensive research, their toxicological profile
Autor:
Karina F. Zoccal, Luiz G. Gardinassi, Karla C. F. Bordon, Eliane C. Arantes, Sylvie Marleau, Huy Ong, Lúcia H. Faccioli
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Over 1 million cases of scorpion stings are estimated every year, whereas current treatment is limited to antivenom serum combined with supportive therapy. Tityus serrulatus scorpion venom (TsV) is composed of diverse molecules, including toxins that
Externí odkaz:
https://doaj.org/article/51d187fa6211407a92e65c8a6d1a5ab0
Autor:
David N. Huynh, Hanan Elimam, Valérie L. Bessi, Liliane Ménard, Yan Burelle, Riccarda Granata, André C. Carpentier, Huy Ong, Sylvie Marleau
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2019)
Unacylated ghrelin (UAG), the most abundant form of ghrelin in circulation, has been shown to exert cardioprotective effect in experimental cardiopathies. The present study aimed to investigate the cardioprotective effect of a linear bioactive fragme
Externí odkaz:
https://doaj.org/article/1d1f6ecd9b784e4d9f723ea621474e82
Autor:
Victor Brito, Katia Mellal, Karina F. Zoccal, Yosdel Soto, Liliane Ménard, Roger Sarduy, Lucia H. Faccioli, Huy Ong, Ana M. Vázquez, Sylvie Marleau
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The retention of lipoprotein particles in the intima, in particular to glycosaminoglycan side chains of proteoglycans, is a critical step in atherosclerosis initiation. Administration of chP3R99, a chimeric mouse/human monoclonal antibody inducing an
Externí odkaz:
https://doaj.org/article/62e2d75f3c024ff18293a15f1dde3eae
Autor:
Sylvie Marleau, Catherine Michaud, Davide Brambilla, Huy Ong, Sébastien Sauvé, Xavier Banquy, Cloé L. Esposito, Elise Laszlo, Sung Vo Duy, Araceli Garcia Ac
Publikováno v:
Talanta. 233
Growth hormone-releasing peptide-6 (GHRP-6) is part of a group of small synthetic peptides with potent GH-releasing activity that have gained attention in the last two decades by virtue of their cyto- and cardioprotective effects. Despite numerous pr