Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Sylvie, Mader"'
Autor:
null Rim Bouchelaghem, null Sylvie Mader, null Louis Gaboury, null Mahfoud Messarah, null Mahieddine Boumendjel, null Amel Boumendjel
Publikováno v:
Cellular and Molecular Biology. 68:113-124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50e67f4432bc6162ff5da4c1bd4dad3
https://doi.org/10.14715/cmb/2022.68.9.18
https://doi.org/10.14715/cmb/2022.68.9.18
Publikováno v:
Cells, Vol 10, Iss 11, p 2966 (2021)
Estrogen receptor alpha (ERα, NR3A1) contributes through its expression in different tissues to a spectrum of physiological processes, including reproductive system development and physiology, bone mass maintenance, as well as cardiovascular and cen
Externí odkaz:
https://doaj.org/article/7dae74f0b9bd4c5fad8ef2ccf2556dd4
Autor:
Mark Basik, Olga Aleynikova, Sylvie Mader, David Laperrière, Saima Hassan, Dana Keilty, Marguerite Buchanan, Patricia N. Tonin, Alexander Klimowicz, Anthony Magliocco, Isabelle Sirois, Catherine Chabot, Aline Mamo, Luca Cavallone, Stéphanie Légaré
SPEN is mutated in T47D cells (S1); SPEN is down-regulated and mutated in breast cancer (S2); SPEN regulates cell growth and survival (S3); SPEN knockdown in triple negative breast cancer cell lines limits proliferation (S4); SPEN regulates cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2b44563d7e144bbd73c4387332a821
https://doi.org/10.1158/0008-5472.22404962.v1
https://doi.org/10.1158/0008-5472.22404962.v1
Autor:
Mark Basik, Olga Aleynikova, Sylvie Mader, David Laperrière, Saima Hassan, Dana Keilty, Marguerite Buchanan, Patricia N. Tonin, Alexander Klimowicz, Anthony Magliocco, Isabelle Sirois, Catherine Chabot, Aline Mamo, Luca Cavallone, Stéphanie Légaré
Legends for Supplemental Figures S1-S8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc592138a0cac817a15520c622cd81c5
https://doi.org/10.1158/0008-5472.22404965
https://doi.org/10.1158/0008-5472.22404965
Autor:
Mark Basik, Olga Aleynikova, Sylvie Mader, David Laperrière, Saima Hassan, Dana Keilty, Marguerite Buchanan, Patricia N. Tonin, Alexander Klimowicz, Anthony Magliocco, Isabelle Sirois, Catherine Chabot, Aline Mamo, Luca Cavallone, Stéphanie Légaré
Clinical data (S1); Expression levels of SPEN and PGR as evaluated with DNA microarrays (S2); IC50 values of SPEN-overexpressing T47D clones, SPEN-silenced MCF-7 clones and their respective controls (S3); Loss of heterozysity assessment using polymor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699c356f26eb4675670e5757a6d16f5b
https://doi.org/10.1158/0008-5472.22404959
https://doi.org/10.1158/0008-5472.22404959
Publikováno v:
Cells, Vol 9, Iss 8, p 1765 (2020)
Breast cancer is the 2nd leading cause of cancer-related death among women. Increased risk of breast cancer has been associated with high dietary cholesterol intake. However, the underlying mechanisms are not known. The nuclear receptor, estrogen-rel
Externí odkaz:
https://doaj.org/article/48f32b144bef49c2bd830124147a24a9
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5453
Estrogen receptor alpha (ERα) expression in ~2/3 breast tumors selects patients for hormonal therapies. Tumors negative for ERα but positive for the progesterone receptor (PR, encoded by PGR) have also been candidates for ER-targeting therapies, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c54c2ffa81f25a30f67dd17048e594
Publikováno v:
The Journal of biological chemistry. 299(1)
Antiestrogens (AEs) are used to treat all stages of estrogen receptor (ER)-positive breast cancer. Selective estrogen receptor modulators such as tamoxifen have tissue-specific partial agonist activity, while selective estrogen receptor downregulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33dbb25bf559b54a1f776923ec4750a
https://pubmed.ncbi.nlm.nih.gov/36460099
https://pubmed.ncbi.nlm.nih.gov/36460099
Autor:
Eric Audemard, Jonathan Boucher, Sebastien Lemieux, Sylvie Mader, Philippe Roux, Salwa Haidar
Publikováno v:
Journal of the Endocrine Society. 6:A882-A882
The transcription factor (TF) GRHL2 controls normal epithelial differentiation in different tissues. It is expressed in all breast cancer subtypes except those with a mesenchymal phenotype (claudin-low subtype), where its ectopic expression leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::667763e097a1fada02e3638bf6da24d6
https://doi.org/10.1210/jendso/bvac150.1826
https://doi.org/10.1210/jendso/bvac150.1826
Autor:
Muriel Laine, David J. Hosfield, Sydney Cush, Sean W. Fanning, Sylvie Mader, Estelle Nduwke, Sandra Weber, Madline Sauvage, Ross Han, Geoffrey L. Greene, Nan-Sheng Li, Emily Sullivan
Chemical manipulation of estrogen receptor alpha ligand binding domain structural mobility tunes receptor lifetime and influences breast cancer therapeutic activities. Selective estrogen receptor modulators (SERMs) extend ERα cellular lifetime, accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a775eabcfcda9ac7c8a73bdd3d62b9
https://doi.org/10.1101/2021.08.27.457901
https://doi.org/10.1101/2021.08.27.457901