Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Sylvie, Lorthois"'
Autor:
David Pastor-Alonso, Maxime Berg, Franck Boyer, Natalie Fomin-Thunemann, Michel Quintard, Yohan Davit, Sylvie Lorthois
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1011973 (2024)
Recent progresses in intravital imaging have enabled highly-resolved measurements of periarteriolar oxygen gradients (POGs) within the brain parenchyma. POGs are increasingly used as proxies to estimate the local baseline oxygen consumption, which is
Externí odkaz:
https://doaj.org/article/a5f730a4241149e68bf1252b7d58fce9
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Blood microcirculation supplies neurons with oxygen and nutrients, and contributes to clearing their neurotoxic waste. Here, the authors analyse blood flow simulations to establish the physical laws linking the microvascular architecture to the macro
Externí odkaz:
https://doaj.org/article/376a3195861346d29d773184244227e7
Autor:
Adlan Merlo, Sylvain Losserand, François Yaya, Philippe Connes, Magalie Faivre, Sylvie Lorthois, Christophe Minetti, Elie Nader, Thomas Podgorski, Céline Renoux, Gwennou Coupier, Emilie Franceschini
Publikováno v:
Biophysical Journal
Biophysical Journal, In press, ⟨10.1016/j.bpj.2022.12.005⟩
Biophysical Journal, In press, ⟨10.1016/j.bpj.2022.12.005⟩
International audience; On-chip study of blood flow has emerged as a powerful tool to assess the contribution of each component of blood to its overall function. Blood has indeed many functions, from gas and nutrient transport to immune response and
Autor:
Amy F. Smith, Vincent Doyeux, Maxime Berg, Myriam Peyrounette, Mohammad Haft-Javaherian, Anne-Edith Larue, John H. Slater, Frédéric Lauwers, Pablo Blinder, Philbert Tsai, David Kleinfeld, Chris B. Schaffer, Nozomi Nishimura, Yohan Davit, Sylvie Lorthois
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Despite the key role of the capillaries in neurovascular function, a thorough characterization of cerebral capillary network properties is currently lacking. Here, we define a range of metrics (geometrical, topological, flow, mass transfer, and robus
Externí odkaz:
https://doaj.org/article/5c6eea44e62e4684b2c3294c3d750b78
Autor:
Annika Erika Huber, Mohammad Haft-Javaherian, Maxime Berg, Asheesh Lanba, Sylvie Lorthois, Taryn L. Bauerle, Nozomi Nishimura
The xylem network, the water conduction system in wood determines the ability of trees to avoid hydraulic failure during drought stress. The capability to withstand embolisms, disruptions of the water column by gas bubbles that contribute to hydrauli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f026da49ee0c46c7d716757c69cbc5e1
https://doi.org/10.1101/2023.01.10.523508
https://doi.org/10.1101/2023.01.10.523508
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0189474 (2018)
Aging or cerebral diseases may induce architectural modifications in human brain microvascular networks, such as capillary rarefaction. Such modifications limit blood and oxygen supply to the cortex, possibly resulting in energy failure and neuronal
Externí odkaz:
https://doaj.org/article/cebe7f1b65424632b41cdef27f3ad4bd
Autor:
Sophie Guillotin, Alexandra Vallet, Sylvie Lorthois, Philippe Cestac, Eric Schmidt, Nicolas Delcourt
Publikováno v:
Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2022, 77 (7), pp.1335-1343. ⟨10.1093/gerona/glac074⟩
Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2022, 77 (7), pp.1335-1343. ⟨10.1093/gerona/glac074⟩
Frailty is a geriatric syndrome that combines physiological decline, disruptions of homeostatic mechanisms across multiple physiologic systems and thus, strong vulnerability to further pathological stress. Previously, we provided the first evidence t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f70dc2ee53ac71e271cebb95351bbf6
https://hal.science/hal-03812581/file/JGBS-2021-256.R2_Proof_fl.pdf
https://hal.science/hal-03812581/file/JGBS-2021-256.R2_Proof_fl.pdf
Publikováno v:
Soft Matter
The physics of blood flow in small vessel networks is dominated by the interactions between Red Blood Cells (RBCs), plasma and blood vessel walls. The resulting couplings between the microvessel network architecture and the heterogeneous distribution
Nephrocalcinosis in very low birth weight infants: incidence, associated factors, and natural course
Publikováno v:
Pediatric Nephrology
Pediatric Nephrology, Springer Verlag, 2022, ⟨10.1007/s00467-021-05417-w⟩
Pediatric Nephrology, Springer Verlag, 2022, ⟨10.1007/s00467-021-05417-w⟩
Background Preterm kidney is exposed to various exogenous factors that may impact its function such as nephrotoxic drugs or nephrocalcinosis. We investigated prevalence and risk factors of nephrocalcinosis (NC) in recently born very low birth weight
Publikováno v:
Brain Multtiphysics
Brain Multtiphysics, Elsevier, 2021, 2, pp.100028. ⟨10.1016/j.brain.2021.100028⟩
Brain Multiphysics, Vol 2, Iss, Pp 100028-(2021)
Brain Multtiphysics, 2021, 2, pp.100028. ⟨10.1016/j.brain.2021.100028⟩
Brain Multtiphysics, Elsevier, 2021, 2, pp.100028. ⟨10.1016/j.brain.2021.100028⟩
Brain Multiphysics, Vol 2, Iss, Pp 100028-(2021)
Brain Multtiphysics, 2021, 2, pp.100028. ⟨10.1016/j.brain.2021.100028⟩
In cerebrovascular networks, some vertices are more connected to each other than with the rest of the vasculature, defining a community structure. Here, we introduce a class of model networks built by rewiring Random Regular Graphs, which enables to