Výsledky vyhledávání - "Sylvie, Carmona"

TWEAK and TNFα, Both TNF Ligand Family Members and Multiple Sclerosis-Related Cytokines, Induce Distinct Gene Response in Human Brain Microvascular Endothelial Cells

Autor: Delphine Stephan, Anais Roger, Jehanne Aghzadi, Sylvie Carmona, Christophe Picard, Jean-Philippe Dales, Sophie Desplat-Jégo

Publikováno v: Genes
Genes, 2022, 13 (10), pp.1714. ⟨10.3390/genes13101714⟩
Genes; Volume 13; Issue 10; Pages: 1714

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a member of the TNF ligand family involved in various diseases including brain inflammatory pathologies such as multiple sclerosis. It has been demonstrated that TWEAK can induce cerebro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2465316442fd8de58a2ef233657d40
https://hal.science/hal-03838054

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Inhibition of E-selectin expression on the surface of endothelial cells inhibits hepatocellular carcinoma growth by preventing tumor angiogenesis

Autor: Elisabeth Jouve, René Gerolami, Assou El-Battari, Patrick Borentain, Sylvie Carmona, Sylvie Mathieu

Publikováno v: Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology, Springer Verlag, 2016, 77 (4), pp.847-856. ⟨10.1007/s00280-016-3006-x⟩

Interactions between endothelial and tumor cells via E-selectin and sialyl Lewis x (sLex) have been suggested to play a significant role in the development of metastasis and tumor growth. In this work, we tested whether inhibition of E-selectin expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9accc37772a49926fe507e9b38fee4ff
https://doi.org/10.1007/s00280-016-3006-x

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A squalamine derivative, NV669, as a novel PTP1B inhibitor

Autor: Sylvie, Carmona, Jean-Michel, Brunel, Rénaté, Bonier, Véronique, Sbarra, Stéphane, Robert, Patrick, Borentain, Dominique, Lombardo, Eric, Mas, René, Gerolami

Publikováno v: Oncotarget

NV669 is an aminosterol derived from squalamine found to possess strong anticancer effects. The aim of this study was to investigate NV669’s beneficial effects on human pancreatic and hepatic cancer models and to decipher the cellular and molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3795837fe00afedd455ce43f0ab7c0b0
https://pubmed.ncbi.nlm.nih.gov/31803360

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Introducing α(1,2)-linked fucose into hepatocarcinoma cells inhibits vasculogenesis and tumor growth

Autor: Lydie Crescence, René Gerolami, Ossarath Kol, Sylvie Carmona, Patrick Borentain, Assou El-Battari, Stéphane Garcia, Sylvie Mathieu, José Luis

Publikováno v: International Journal of Cancer. 121:1680-1689

The glycoantigen sialyl-Lewis x (sLex) and its isomer sialy-Lewis a (sLea) are frequently associated with advanced states of cancer and metastasis. In a previous work, we have shown that hepatocarcinoma cells (HCC) HepG2 interact with the endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19efc508dd99f05b0812000b2335ceb
https://doi.org/10.1002/ijc.22797

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Apoptotic death concurrent with CD3 stimulation in primary human CD8+ T lymphocytes: a role for endogenous granzyme B

Autor: Anna Senik, Sylvie Carmona, Nicolas Bidère, Aurore Devocelle, Bernard Charpentier, Mireille Laforge

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2006, 176 (7), pp.3966-3977. ⟨10.4049/jimmunol.176.7.3966⟩

We exposed primary CD8+ T cells to soluble CD3 mAb plus IL-2 and limited numbers of monocytes (3%). These cells were activated but concurrently subjected to ongoing apoptosis (∼25% were apoptotic from day 2 of culture). However, their costimulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7823e7b9b90689ba769574cd86de4296
https://pubmed.ncbi.nlm.nih.gov/16547231

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A role for CD2 antibodies (BTI-322 and its humanized form) in the in vivo elimination of human T lymphocytes infiltrating an allogeneic human skin graft in SCID mice: an Fcgamma receptor-related mechanism involving co-injected human NK cells

Autor: Hervé Bazin, Christophe Baron, Dominique Latinne, Matthieu Rouleau, Sylvie Carmona, Anna Senik, Renaud Snanoudj, Bernard Charpentier, Nicolas Bidère

Publikováno v: Transplantation. 78(1)

BACKGROUND: Pilot clinical studies have shown that the rat anti-human-CD2 monoclonal antibody, LoCD2a/BTI-322, can efficiently prevent and treat acute kidney rejection. However, the in vivo mechanism by which it prevents allograft rejection has not b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff9eeb28dcade068fede804a80e112d
https://pubmed.ncbi.nlm.nih.gov/15257038

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Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

Autor: Sylvie Carmona, Nicolas Bidère, Mireille Laforge, Anna Senik, Céline Dumont, Hans Kristian Lorenzo, Francis Harper

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2003, 278 (33), pp.31401-31411. ⟨10.1074/jbc.M301911200⟩

Activated human T lymphocytes exposed to apoptotic stimuli targeting mitochondria (i.e. staurosporine), enter an early, caspase-independent phase of commitment to apoptosis characterized by cell shrinkage and peripheral chromatin condensation. We sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07ac6446d806860484ff0269fac661e
https://pubmed.ncbi.nlm.nih.gov/12782632

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Akademický článek

A Role for CD2 Antibodies (BTI-322 and its Humanized Form) in the in vivo Elimination of Human T Lymphocytes Infiltrating an Allogeneic Human Skin Graft in SCID Mice: An Fc? Receptor-Related Mechanism Involving Co-Injected Human NK Cells.

Autor: Renaud Snanoudj, Matthieu Rouleau, Nicolas Bidre, Sylvie Carmona, Christophe Baron, Dominique Latinne, Herv Bazin, Bernard Charpentier, Anna Senik

Publikováno v: Transplantation; Jul2004, Vol. 78 Issue 1, p50-58, 9p

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A glycosyltransferase-enriched reconstituted membrane system for the synthesis of branched O-linked glycans in vitro

Autor: Sandrine Susini, Sylvie Carmona, Assou El-Battari, Charlotte Jeanneau, Sylvie Mathieu

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. (6):1509-1519

Mimicking the biochemical reactions that take place in cell organelles is becoming one of the most important challenges in biological chemistry. In particular, reproducing the Golgi glycosylation system in vitro would allow the synthesis of bioactive

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