Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sylvia T. Hoffstein"'
Autor:
Gary J Marks, Kei-Lai L Fong, Sylvia T. Hoffstein, Timothy K. Hart, Glenn F. Rush, Peter J. Bugelski
Publikováno v:
Thrombosis and Haemostasis. 63:251-258
SummaryThe uptake and internalization of tissue-type plasminogen activator (t-PA) by freshly isolated rat hepatocytes was investigated. Electron microscopic examination of the uptake of t-PA-colloidal gold conjugates (t-PA-gold) by isolated rat hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e7034d1596782498cc43ca339fd5681
https://doi.org/10.1055/s-0038-1645204
https://doi.org/10.1055/s-0038-1645204
Autor:
Luciano Ramos, Peter J. Bugelski, Timothy K. Hart, Oka Melvin Susumu, Mitchell E. Reff, Gary J Marks, Doris Gennaro, Sylvia T. Hoffstein
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 198(1)
Tissue-type plasminogen activator (tPA) is a serine protease which cleaves plasminogen to its active form, plasmin. tPA plays a physiologic role in hemostasis, wound healing, and embryogenesis. Therapeutically, recombinant human tPA is used as a thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54a93b2eaaab681ce45f0e2b487d2a9
https://pubmed.ncbi.nlm.nih.gov/1909792
https://pubmed.ncbi.nlm.nih.gov/1909792
Publikováno v:
Prostaglandins. 31:205-215
LTB4 (5s, 12R dihdroxy-6, 14-CIS-8, 10-trans-eicosatetraenoic acid) formed in activated neutrophils by lipoxygenation of arachidonic acid is an extremely potent chemotaxin. We examined structural requirements for chemotactic and aggregatory activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398c8ecea94041ef654bcc57317f4cb0
https://doi.org/10.1016/0090-6980(86)90047-x
https://doi.org/10.1016/0090-6980(86)90047-x
Publikováno v:
Arthritis & Rheumatism. 31:1421-1428
Tritiated arachidonic acid (3H-AA)-labeled rat synovial fibroblasts stimulated with human recombinant interleukin-1 beta (rIL-1 beta) released incorporated radiolabel in a time-dependent and dose-dependent manner, with labeled prostaglandins represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89cf9953ec24a889c3d8de5ff763b84f
https://doi.org/10.1002/art.1780311112
https://doi.org/10.1002/art.1780311112
Autor:
Don E. Griswold, L. M. Hillegass, P. J. Marshall, Paul Elliot Bender, E. F. Webb, Sylvia T. Hoffstein, Nabil Hanna
Publikováno v:
Inflammation. 13:727-739
The mode of action of the dual inhibitors of eicosanoid metabolism, SK&F 86002 and SK&F 104493 was evaluated on inflammatory cell infiltration induced in mice by carrageenan, monosodium urate crystals, and arachidonic acid. The results were compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1cfa9f4f113ae571b4f9e285c3bd6e
https://doi.org/10.1007/bf00914315
https://doi.org/10.1007/bf00914315
Autor:
Sylvia T. Hoffstein
Publikováno v:
The Journal of Immunology. 123:1395-1402
Most cell-associated calcium exists as bound rather than free ionized calcium. Since calcium and other cations are important regulators of polymorphonuclear leukocyte (PMN) function, the localization of bound calcium in resting PMN and its redistribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348e0b97b9b02b8d35809ef512077427
https://doi.org/10.4049/jimmunol.123.3.1395
https://doi.org/10.4049/jimmunol.123.3.1395
Publikováno v:
Inflammation. 9:425-437
Many stimuli induce neutrophils to undergo an oxidative burst and generate toxic oxygen metabolites. The major products are O2- and H2O2, the latter being presumed to arise by spontaneous dismutation of the former. If H2O2 were indeed derived exclusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e33729188367ead99ee41ec8dde4b9
https://doi.org/10.1007/bf00916342
https://doi.org/10.1007/bf00916342
Publikováno v:
The Journal of Immunology. 115:665-670
The complement component, C5a provokes the selective release of granule-associated enzymes from intact, viable cytochalasin B-treated human polymorphonuclear leukocytes (PMN) in the absence of phagocytosis or cellular adherence to surfaces. Consequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0427db94b84402b53cb10022e837f82f
https://doi.org/10.4049/jimmunol.115.3.665
https://doi.org/10.4049/jimmunol.115.3.665
Publikováno v:
Biochemical and biophysical research communications. 142(1)
Stimulation of [3H]-arachidonic acid labeled human synovial cells with 3.0 X 10(-10)M recombinant interleukin-1 or tumor necrosis factor resulted in the release of incorporated radiolabel (41.1% and 27.7% respectively). Analysis of [3H]-arachidonic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb58065e0681ad65a5a22c0dd49e209
https://pubmed.ncbi.nlm.nih.gov/3028403
https://pubmed.ncbi.nlm.nih.gov/3028403
Autor:
Dian‐Jun ‐J Li, Mark Lynch, David Reiman, Deborah L. Trainer, Leo F. Faucette, George Poste, John Feild, Margery Chaikin, Charles Buscarino, Francis L. McCabe, Doris Gennaro, Sylvia T. Hoffstein, Mario A. Anzano, Russell G. Greig, Thomas Kline
Publikováno v:
International journal of cancer. 41(2)
To establish well-characterized cellular reagents for the study of colon carcinoma, we have examined 19 human colorectal carcinoma cell lines with regard to morphology, ultrastructure, expression of tumor-associated antigens, proliferative capacity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f40ee14dfbb107a0e436aa8120b6cd
https://pubmed.ncbi.nlm.nih.gov/3338874
https://pubmed.ncbi.nlm.nih.gov/3338874