Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sylvia T, Nurnberg"'
Autor:
Sylvia T Nurnberg, Marie A Guerraty, Robert C Wirka, H Shanker Rao, Milos Pjanic, Scott Norton, Felipe Serrano, Ljubica Perisic, Susannah Elwyn, John Pluta, Wei Zhao, Stephanie Testa, YoSon Park, Trieu Nguyen, Yi-An Ko, Ting Wang, Ulf Hedin, Sanjay Sinha, Yoseph Barash, Christopher D Brown, Thomas Quertermous, Daniel J Rader
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008538 (2020)
Genome-wide association studies have identified multiple novel genomic loci associated with vascular diseases. Many of these loci are common non-coding variants that affect the expression of disease-relevant genes within coronary vascular cells. To i
Externí odkaz:
https://doaj.org/article/b7dd34ae270f46b99fac5cb149310b65
Autor:
Sylvia T Nurnberg, Karen Cheng, Azad Raiesdana, Ramendra Kundu, Clint L Miller, Juyong B Kim, Komal Arora, Ivan Carcamo-Oribe, Yiqin Xiong, Nikhil Tellakula, Vivek Nanda, Nikitha Murthy, William A Boisvert, Ulf Hedin, Ljubica Perisic, Silvia Aldi, Lars Maegdefessel, Milos Pjanic, Gary K Owens, Michelle D Tallquist, Thomas Quertermous
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005155 (2015)
Recent genome wide association studies have identified a number of genes that contribute to the risk for coronary heart disease. One such gene, TCF21, encodes a basic-helix-loop-helix transcription factor believed to serve a critical role in the deve
Externí odkaz:
https://doaj.org/article/634f0f095de147ef80655c3a26fbf021
Autor:
Sanjay Sinha, Felipe Serrano, Marie A Guerraty, Thomas Quertermous, Yi-An Ko, Milos Pjanic, Wei Zhao, Scott Norton, Yoseph Barash, Daniel J. Rader, Ulf Hedin, John Pluta, Robert C. Wirka, Christopher D. Brown, Trieu Nguyen, Sylvia T. Nurnberg, Ljubica Perisic, Stephanie Testa, Ting Wang, Susannah Elwyn, H. Shanker Rao, YoSon Park
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 1, p e1008538 (2020)
PLoS Genetics, Vol 16, Iss 1, p e1008538 (2020)
Genome-wide association studies have identified multiple novel genomic loci associated with vascular diseases. Many of these loci are common non-coding variants that affect the expression of disease-relevant genes within coronary vascular cells. To i
Publikováno v:
Circulation. 138
Introduction: Genome-wide association studies have identified rs2107595, a non-coding locus on chromosome 9 between HDAC9 and Twist1 genes, as a risk allele for several vascular phenotypes, including Coronary Artery Disease (CAD). Rs2107595 has, more
Autor:
Stephen B. Montgomery, Ting Wang, Michael J. Gloudemans, Susannah Elwyn, Sylvia T. Nurnberg, Trieu Nguyen, Daniel J. Rader, Clint L. Miller, Boxiang Liu, Victor G. Castano, Erik Ingelsson, Abhiram Rao, Milos Pjanic, Thomas Quertermous
Coronary artery disease (CAD) is the leading cause of death globally. Genome-wide association studies (GWAS) have identified more than 95 independent loci that influence CAD risk, most of which reside in non-coding regions of the genome. To interpret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d772ed7e88dbb5b5db1e662be3ddb331
https://doi.org/10.1101/309559
https://doi.org/10.1101/309559
Autor:
Sylvia T Nurnberg, YoSon Park, Jordi Vaquero-Garcia, Milos Pjanic, Susanna Elwyn, John Pluta, Wei Zhao, Stephanie Testa, Yoseph Barash, Christopher Brown, Thomas Quertermous, Daniel Rader
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
The most recent Genome-wide Association Study (GWAS) meta-analysis has reported a total of 58 genomic loci to be statistically significantly associated with genetic susceptibility to Coronary Artery Disease (CAD) (Consortium, 2015). Many of these loc
Autor:
Dominique Gauguier, Ruth McPherson, Anuj Goel, Donald W. Bowden, Nancy L. Pedersen, WeangKee Ho, Danish Saleheen, Nilesh J. Samani, Marcus Edi Kleber, Michael A. Province, Albert V. Smith, Christopher J. O'Donnell, Jeanette Erdmann, Hooman Allayee, Asif Rasheed, Mary F. Feitosa, Vilmundur Gudnason, Jaspal S. Kooner, Christopher P. Nelson, Muredach P. Reilly, Winfried März, George V. Dedoussis, Wei Zhao, Markus Perola, Alexandre F.R. Stewart, Veikko Salomaa, John C. Chambers, Alistair S. Hall, K. Stefansson, Robert C. Bauer, Panos Deloukas, Charles C. White, Daniel J. Rader, Eirini Marouli, Robert A. Scott, Sylvia T. Nurnberg, Stavroula Kanoni, Andrea Ganna, Anni Joensuu, Svati H. Shah, Juha Sinisalo, Gudmar Thorleifsson, Jing Hua Zhao, Lingyao Zeng, Kari Kuulasmaa, Nicholas J. Wareham, Rona J. Strawbridge, Jane F. Ferguson, Philippe M. Frossard, Weihua Zhang, Pierre Zalloua, Kristy Ou, Ulf de Faire, Martin Farrall, Sanaz Sedaghat, Robin Young, Amanda J. Cox, Lars Lind, Christina Willenborg, K. Kristiansson, Erik Ingelsson, Colin N. A. Palmer, Jaana Hartiala, Abbas Dehghan, Natalie van Zuydam, Sekar Kathiresan, John Thompson, Ron Do, Heribert Schunkert, Thorsten Kessler
Publikováno v:
Circulation, 135(24), 2336-+. Lippincott Williams & Wilkins
Background: Common diseases such as coronary heart disease (CHD) are complex in etiology. The interaction of genetic susceptibility with lifestyle factors may play a prominent role. However, gene-lifestyle interactions for CHD have been difficult to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c74221fb90e0d4da766e7deffdfb959
https://pure.eur.nl/en/publications/47da0cef-434f-40c4-891f-ba9a4a81e03e
https://pure.eur.nl/en/publications/47da0cef-434f-40c4-891f-ba9a4a81e03e
Autor:
Danish, Saleheen, Wei, Zhao, Robin, Young, Christopher P, Nelson, WeangKee, Ho, Jane F, Ferguson, Asif, Rasheed, Kristy, Ou, Sylvia T, Nurnberg, Robert C, Bauer, Anuj, Goel, Ron, Do, Alexandre F R, Stewart, Jaana, Hartiala, Weihua, Zhang, Gudmar, Thorleifsson, Rona J, Strawbridge, Juha, Sinisalo, Stavroula, Kanoni, Sanaz, Sedaghat, Eirini, Marouli, Kati, Kristiansson, Jing, Hua Zhao, Robert, Scott, Dominique, Gauguier, Svati H, Shah, Albert Vernon, Smith, Natalie, van Zuydam, Amanda J, Cox, Christina, Willenborg, Thorsten, Kessler, Lingyao, Zeng, Michael A, Province, Andrea, Ganna, Lars, Lind, Nancy L, Pedersen, Charles C, White, Anni, Joensuu, Marcus, Edi Kleber, Alistair S, Hall, Winfried, März, Veikko, Salomaa, Christopher, O'Donnell, Erik, Ingelsson, Mary F, Feitosa, Jeanette, Erdmann, Donald W, Bowden, Colin N A, Palmer, Vilmundur, Gudnason, Ulf De, Faire, Pierre, Zalloua, Nicholas, Wareham, John R, Thompson, Kari, Kuulasmaa, George, Dedoussis, Markus, Perola, Abbas, Dehghan, John C, Chambers, Jaspal, Kooner, Hooman, Allayee, Panos, Deloukas, Ruth, McPherson, Kari, Stefansson, Heribert, Schunkert, Sekar, Kathiresan, Martin, Farrall, Philippe, Marcel Frossard, Daniel J, Rader, Nilesh J, Samani, Muredach P, Reilly
Publikováno v:
Circulation. 135(24)
Common diseases such as coronary heart disease (CHD) are complex in etiology. The interaction of genetic susceptibility with lifestyle factors may play a prominent role. However, gene-lifestyle interactions for CHD have been difficult to identify. He
Autor:
Susannah Elwyn, Sylvia T. Nurnberg, Joebert Rosal, Daniel J. Rader, Stephanie Testa, Wei Zhao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Genome-wide association studies (GWAS) have identified rs2107595 as association SNP for both stroke and cardiovascular disease. This polymorphism is located proximal to the HDAC9 gene, with TWIST1 106kb downstream as the next closest gene in the reco
Autor:
Marella F. T. R. de Bruijn, Willem H. Ouwehand, Judith Schütte, Victoria Moignard, Huange Wang, Mun Chiang Chan, Rebecca Hannah, Joey Riepsaame, Nicola Bonzanni, Stella Antoniou, Silvia Basilico, Nicola K. Wilson, Andrew Jarratt, Sylvia T. Nurnberg, Berthold Göttgens, Fernando J Calero-Nieto, Sarah Kinston
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Transcription factor (TF) networks determine cell-type identity by establishing and maintaining lineage-specific expression profiles, yet reconstruction of mammalian regulatory network models has been hampered by a lack of comprehensive functional va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2fb1f4c98d49f6d8d9dd69b003da17
https://www.repository.cam.ac.uk/handle/1810/253879
https://www.repository.cam.ac.uk/handle/1810/253879