Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sylvia Styhler"'
Autor:
Marco Di Fruscio, Eva Wikholm, Paul Lasko, Marie-Chloé Boulanger, Sylvia Styhler, Stéphane Richard
Publikováno v:
Proceedings of the National Academy of Sciences. 100:1814-1819
The Drosophila kep1 gene encodes an RNA binding protein related to the murine QUAKING apoptotic inducer. We have previously shown that kep1 can induce apoptosis when transfected into different cell lines. To better define the role of Kep1 in apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079b74940c050cf52d13d7361f934532
https://doi.org/10.1073/pnas.0236048100
https://doi.org/10.1073/pnas.0236048100
Publikováno v:
Developmental Cell. 3(6):865-876
VASA (VAS), a key protein in establishing the specialized translational activity of the Drosophila pole plasm, accumulates at the posterior pole of the developing oocyte. We identified a gene, gustavus (gus), that encodes a protein that interacts wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412d3040196855ea4beb60ff5413fe07
Autor:
Jeffrey M. Besterman, Amal Wahhab, Martin Allan, Anne-Christine Goulet, Guillaume Larouche, Marie-France Robert, Eric Therrien, Natalie Nguyen, Sylvia Styhler, Hannah Nguyen, Sukhdev Manku
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(23)
We have identified the N(1)-benzyl-N(2)-methylethane-1,2-diamine unit as a substitute for the (S)-alanine benzylamide moiety for the design of co-activator associated arginine methyltransferase 1 (CARM1) inhibitors. The potency of these inhibitors is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7f37c5886323445e6e536fa6056fc0
https://pubmed.ncbi.nlm.nih.gov/19836951
https://pubmed.ncbi.nlm.nih.gov/19836951
Autor:
A. Robert MacLeod, Robert Deziel, Eric Therrien, Anne-Christine Goulet, Sylvia Styhler, Sukhdev Manku, Gabi Rahil, Hannah Nguyen, Andrea J. Petschner, Martin Allan, Natalie Nguyen, Jeffrey M. Besterman, Amal Wahhab, Marie-France Robert
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(4)
A series of N-benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides targeting co-activator associated arginine methyltransferase 1 (CARM1) have been designed and synthesized. The potency of these inhibitors was influenced by the nature o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aca66baaf7a8d920ff206061fcb2062
https://pubmed.ncbi.nlm.nih.gov/19131248
https://pubmed.ncbi.nlm.nih.gov/19131248
Publikováno v:
Biological Sciences Publications
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
The Drosophila gene vasa is required for pole plasm assembly and function, and also for completion of oogenesis. To investigate the role of vasa in oocyte development, we generated a new null mutation of vasa, which deletes the entire coding region.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f1ae8bd737ef4b48d1cb8eb5183aa8
https://scholar.uwindsor.ca/context/biologypub/article/2164/viewcontent/Styhler_et_al.___1998___vasa_is_required_for_GURKEN_accumulation_in_the_oo.pdf
https://scholar.uwindsor.ca/context/biologypub/article/2164/viewcontent/Styhler_et_al.___1998___vasa_is_required_for_GURKEN_accumulation_in_the_oo.pdf
Autor:
Weihua Li, Paul Lasko, Milt Paliordas, Emma E. Saffman, Stéphane Richard, Jarred Chicoine, Sylvia Styhler
Publikováno v:
Biochemistry and Cell Biology. 77:405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0fff88a568910cf9642a7653cbb0a51
https://doi.org/10.1139/o99-903ii
https://doi.org/10.1139/o99-903ii
Autor:
Emma E. Saffman, Jarred Chicoine, Milt Paliordas, Sylvia Styhler, Weihua Li, Stéphane Richard, Paul Lasko
Publikováno v:
Biochemistry and Cell Biology. 77:405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::315b703b45ce9444db7b494728fdac0b
https://doi.org/10.1139/bcb-77-4-405
https://doi.org/10.1139/bcb-77-4-405
Publikováno v:
Scopus-Elsevier
Bicaudal-C (Bic-C) is required during Drosophila melanogaster oogenesis for several processes, including anterior-posterior patterning. The gene encodes a protein with five copies of the KH domain, a motif found in a number of RNA-binding proteins. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cb04295fb85a6f334b23b9d30a1052
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031877789&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031877789&partnerID=MN8TOARS