Targeted overexpression of human α-synuclein in oligodendroglia induces lesions linked to MSA -like progressive autonomic failure

Autor: Sylvia Stemberger, Werner Poewe, Gregor K. Wenning, Nadia Stefanova

Publikováno v: Experimental Neurology

Multiple system atrophy (MSA) is a rare neurodegenerative disease of undetermined cause manifesting with progressive autonomic failure (AF), cerebellar ataxia and parkinsonism due to neuronal loss in multiple brain areas associated with (oligodendro)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7af11fd5f810333535c704f443e6fa

An antibody microarray analysis of serum cytokines in neurodegenerative Parkinsonian syndromes

Autor: Philipp Mahlknecht, Johannes Rainer, Werner Poewe, Markus Reindl, Christoph Grabmer, Sylvia Stemberger, Gregor K. Wenning, Eva Hametner, Rudolf Kirchmair, Christoph Scherfler, Fabienne Sprenger, Klaus Seppi

Publikováno v: Proteome Science
Proteome Science, Vol 10, Iss 1, p 71 (2012)

Background Microarray technology may offer a new opportunity to gain insight into disease-specific global protein expression profiles. The present study was performed to apply a serum antibody microarray to screen for differentially regulated cytokin

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https://pubmed.ncbi.nlm.nih.gov/23173604

List of Contributors

Autor: Ana P.L. Abdala, David H. Adams, Marlies Alvarenga, Amy C. Arnold, Felicia B. Axelrod, Franca Barbic, Peter J. Barnes, Deborah Bauer, Christopher Bell, Eduardo E. Benarroch, Elizabeth M. Berry-Kravis, Luciano Bernardi, Italo Biaggioni, Lori Birder, Virginia L. Brooks, Joan Heller Brown, Geoffrey Burnstock, Michael Camilleri, J.Preston Campbell, Robert M. Carey, Marc G. Caron, Calvin Carter, Priscila A. Cassaglia, Javier G. Castillo, Mark W. Chapleau, Nisha Charkoudian, P. David Charles, Gisela Chelimsky, Thomas Chelimsky, Pei-Wen Cheng, Gilles Clément, Pietro Cortelli, Allen W. Cowley, Leslie Crews, Stephen N. Davis, Thomas L. Davis, William C. de Groat, Vincent G. DeMarco, André Diedrich, Donald J. DiPette, Debra I. Diz, Marcus J. Drake, Rachel C. Drew, Matthias Dütsch, Graeme Eisenhofer, Florent Elefteriou, Fernando Elijovich, Brett A. English, Murray Esler, John Y. Fang, Robert D. Fealey, Stanley Fernandez, Gregory D. Fink, John S. Floras, Roy Freeman, Qi Fu, Liang-Wu Fu, Raffaello Furlan, Alfredo Gamboa, Emily M. Garland, Christopher H. Gibbons, Michael P. Gilbey, Janice L. Gilden, Sid Gilman, David S. Goldstein, Diego A. Golombek, Robert M. Graham, Guido Grassi, Mark D. Grier, Jan T. Groothuis, Blair P. Grubb, Maureen K. Hahn, Julian P.J. Halcox, Robert W. Hamill, Kenneth R. Hande, Yadollah Harati, David G. Harrison, Emma C. Hart, Jacqui Hastings, Luke A. Henderson, Max J. Hilz, Robert Hoeldtke, Shung Tai Ho, Peter Hunter, Keith Hyland, Lauren Hyland, Shahram Izadyar, Joseph L. Izzo, Edwin K. Jackson, Giris Jacob, Wilfrid Jänig, Megan S. Johnson, Carrie K. Jones, James F.X. Jones, Karen M. Joos, Jens Jordan, Michael J. Joyner, Stephen G. Kaler, Sergey Kasparov, Horacio Kaufmann, David Kaye, Ramesh K. Khurana, Chun-Hyung Kim, Kwang-Soo Kim, Kazuto Kobayashi, Nancy L. Kuntz, Tomas Konecny, Andrew Kontak, Cheryl L. Laffer, Andre H. Lagrange, Nora Laiken, Gavin Lambert, Jacques W.M. Lenders, Benjamin D. Levine, Lewis A. Lipsitz, Julian H. Lombard, John C. Longhurst, David A. Low, Phillip A. Low, Chih Cherng Lu, James M. Luther, Vaughan G. Macefield, Belinda H. McCully, James G. McLeod, William M. Manger, Tadaaki Mano, Paul J. Marvar, Eliezer Masliah, Christopher J. Mathias, Mark R. Melson, Douglas F. Milam, Marion C. Mohl, Yaroslav I. Molkov, Margaret Morris, Shaun F. Morrison, Toshiharu Nagatsu, Charles D. Nichols, Lucy Norcliffe-Kaufmann, Vera Novak, Luis E. Okamoto, John W. Osborn, Brian A. Parsons, Julian F.R. Paton, Pallavi P. Patwari, Cecile L. Phan, Fenna T. Phibbs, Nanduri R. Prabhakar, Amanda C. Peltier, Sean M. Peterson, Anthony E Pickering, J.Howard Pratt, Kamal Rahmouni, Satish R. Raj, Casey M. Rand, Heinz Reichmann, Jeff Richards, L.Jackson Roberts, David W. Robertson, Rose Marie Robertson, Michael Robinson, Ilya A. Rybak, Elaine Sanders-Bush, Paola Sandroni, Kyoko Sato, Takayuki Sato, Irwin J. Schatz, Ernesto L. Schiffrin, Ronald Schondorf, Rosemary Schwarz, Gino Seravalle, Robert E. Shapiro, Cyndya Shibao, Virend Somers, Michaela Stampfer, C.Michael Stein, Sylvia Stemberger, Julian Stewart, Lawrence I. Sinoway, James R. Sowers, Sirisha Srikakarlapudi, Kenji Sunagawa, Scott C. Supowit, Palmer Taylor, Jane Thompson, Roland D. Thijs, Rhian M Touyz, Daniel Tranel, Subbulaxmi Trikudanathan, Ching-Jiunn Tseng, Che-Se Tung, Kiren Ubhi, Nikhil Urs, Joseph G. Verbalis, Steven Vernino, Ronald G. Victor, Margaret A. Vizzard, Wanpen Vongpatanasin, B.Gunnar Wallin, Tobias Wang, Qin Wang, Andrew A. Webster, Debra E. Weese-Mayer, Gregor K. Wenning, Adam Whaley-Connell, Wouter Wieling, Gordon H. Williams, Scott Wood, Michael G. Ziegler, Daniel B. Zoccal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::339751ee66d6eee5a7316633f4b04b2f
https://doi.org/10.1016/b978-0-12-386525-0.00149-9

Modelling progressive autonomic failure in MSA: where are we now?

Autor: Gregor K. Wenning, Sylvia Stemberger

Publikováno v: Journal of neural transmission (Vienna, Austria : 1996). 118(5)

Multiple system atrophy (MSA) is a fatal late-onset α-synucleinopathy that presents with features of ataxia, Parkinsonism, and pyramidal dysfunction in any combination. Over the last decade, efforts have been made to develop preclinical MSA testbeds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8a6f93f08374e3b0b3b10d97947107
https://pubmed.ncbi.nlm.nih.gov/21221668