Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sylvia Schütz"'
Publikováno v:
Nature Reviews Microbiology. 4:651-659
MicroRNAs (miRNAs), which can be expressed in a cell-type and tissue-specific manner, can influence the activities of genes that control cell growth and differentiation. Viruses often have clear tissue tropisms, raising the possibility that cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebe18acbcdb2cfef1de5f2498c57a88
https://doi.org/10.1038/nrmicro1473
https://doi.org/10.1038/nrmicro1473
Cells possess mechanisms that permit survival and recovery from stress, several of which regulate the phosphorylation of eukaryotic translation initiation factor 2alpha (eIF2alpha). We identified the human OGFOD1 protein as a novel stress granule com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23ed9c6993adbecc82c918e3477fbcf
https://europepmc.org/articles/PMC2849474/
https://europepmc.org/articles/PMC2849474/
Summary MicroRNAs usually interact with 3′ noncoding regions (3′NCRs) of target mRNAs leading to downregulation of mRNA expression. In contrast, liver-specific microRNA miR-122 interacts with the 5′ end of the hepatitis C virus RNA genome, resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33d897a77573cec13b9afbfa00118d1
https://europepmc.org/articles/PMC3519368/
https://europepmc.org/articles/PMC3519368/
Autor:
Marie Lindholm, Matthew Lawrence, Urs V. Berger, Andreas Petri, Phil Kearney, Ellen Marie Straarup, Sylvia Schütz, Steven R. Gullans, Peter Sarnow, Maj Hedtjärn, Henrik Frydenlund Hansen, Sakari Kauppinen, Susanna Obad, Joacim Elmén, Morten Lindow
Publikováno v:
Nature. 452(7189)
microRNAs (miRNAs) are small regulatory RNAs that are important in development and disease and therefore represent a potential new class of targets for therapeutic intervention. Despite recent progress in silencing of miRNAs in rodents, the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28b5ba950f5eb135e864327e89f9cca
https://pubmed.ncbi.nlm.nih.gov/18368051
https://pubmed.ncbi.nlm.nih.gov/18368051
Autor:
Jan Chemnitz, Joachim Hauber, Ralph H. Kehlenbach, Sylvia Schütz, Christiane Spillner, Marcus Frohme
Publikováno v:
Journal of molecular biology. 358(4)
In metazoans, the nuclear export of bulk mRNAs is mediated by the export receptor TAP, together with its binding partner p15. A number of viral mRNAs, including the unspliced and partially spliced mRNA species of the human immunodeficiency virus (HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43373c1a1b037e164ca0f485693c71a8
https://pubmed.ncbi.nlm.nih.gov/16580684
https://pubmed.ncbi.nlm.nih.gov/16580684
Autor:
Nicole Gas, Sylvia Schütz, Olivier Gadal, Ed Hurt, Daniela Strauss, Johannes Lechner, Herbert Tschochner, Philipp Milkereit, Holger Kühn, Jochen Bassler
Publikováno v:
The Journal of biological chemistry. 278(6)
Formation and nuclear export of 60 S pre-ribosomes requires many factors including the heterodimeric Noc1-Noc2 and Noc2-Noc3 complexes. Here, we report another Noc complex with a specific role in 40 S subunit biogenesis. This complex consists of Noc4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c664d920f81e6eff68fa479af87572f
https://pubmed.ncbi.nlm.nih.gov/12446671
https://pubmed.ncbi.nlm.nih.gov/12446671
Publikováno v:
Metabolism: clinical and experimental. 43(6)
The relationship among “negative” plasma acute-phase proteins (APP), ie, albumin, prealbumin, and transferrin, and “positive” APP, ie, C-reactive protein (CRP), fibrinogen, and orosomucoid, was investigated in patients with acute infectious d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27911cd05bea967bf0cf065cade2f330
https://pubmed.ncbi.nlm.nih.gov/7515458
https://pubmed.ncbi.nlm.nih.gov/7515458
Publikováno v:
Geologische Rundschau. 65:536-557
Die Thiersee- und die Karwendelmulde in den Nordlichen Kalkalpen sind als zwei getrennte, E-W-verlaufende Synklinen entwickelt. Ihre Lange zwischen Kufstein und Mittenwald betragt uber 70 km.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ab5e43d188f65488380d221b64fc2d6
https://doi.org/10.1007/bf01808480
https://doi.org/10.1007/bf01808480
Autor:
Peter Sarnow, Sylvia Schütz
Publikováno v:
Virology. (1):151-157
It has been known for some time that plants and insects use RNA interference (RNAi) as nucleic acid-based immunity against viral infections. However, it was unknown whether mammalian cells employ the RNA interference pathway as an antiviral mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb6e09886402dac5a76bd2216aa4c4a
Publikováno v:
Virology. (2):472-484
Components of cytoplasmic processing bodies (P-bodies) and stress granules can be subverted during viral infections to modulate viral gene expression. Because hepatitis C virus (HCV) RNA abundance is regulated by P-body components such as microRNA mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a514a104110b86def6475fbb7fed02e4