Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sylvia R. Luckner"'
Autor:
Estelle S Baker, Sylvia R Luckner, Kurt L Krause, Paul R Lambden, Ian N Clarke, Vernon K Ward
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30534 (2012)
Human noroviruses are highly infectious viruses that cause the majority of acute, non-bacterial epidemic gastroenteritis cases worldwide. The first open reading frame of the norovirus RNA genome encodes for a polyprotein that is cleaved by the viral
Externí odkaz:
https://doaj.org/article/e7718fb8925746c8b5709ef7dc7c375c
Structural features and kinetic characterization of alanine racemase fromStaphylococcus aureus(Mu50)
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
The tertiary structure and kinetic properties of alanine racemase from Staphylococcus aureus are described and compared to other related alanine racemase structures.
Staphylococcus aureus is an opportunistic Gram-positive bacterium which causes
Staphylococcus aureus is an opportunistic Gram-positive bacterium which causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a3ad7dee43e8cbf3c40a877d3fcf92
https://doi.org/10.1107/s0907444911050682
https://doi.org/10.1107/s0907444911050682
Publikováno v:
Journal of Biological Chemistry. 285:14330-14337
InhA, the enoyl-ACP reductase in Mycobacterium tuberculosis is an attractive target for the development of novel drugs against tuberculosis, a disease that kills more than two million people each year. InhA is the target of the current first line dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c897c2e79421acea7c58169dffc122d9
https://doi.org/10.1074/jbc.m109.090373
https://doi.org/10.1074/jbc.m109.090373
Autor:
Nicole L. Marlenee, B. Gopal Reddy, Peter J. Tonge, Richard A. Bowen, Susan E. Knudson, Richard A. Slayden, Kathleen England, Hao Lu, Dennis L. Knudson, Christopher W. am Ende, Caroline Kisker, James J. Truglio, Sylvia R. Luckner
Publikováno v:
ACS Chemical Biology. 4:221-231
Francisella tularensis is a highly virulent and contagious Gram-negative intracellular bacterium that causes the disease tularemia in mammals. The high infectivity and the ability of the bacterium to survive for weeks in a cool, moist environment hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88fa8bf7fcd94b70feb7ea70bc962db
https://doi.org/10.1021/cb800306y
https://doi.org/10.1021/cb800306y
Autor:
Vernon K. Ward, Ian N. Clarke, Estelle S. Baker, Sylvia R. Luckner, Paul R. Lambden, Kurt L. Krause
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30534 (2012)
PLoS ONE
PLoS ONE
Human noroviruses are highly infectious viruses that cause the majority of acute, non-bacterial epidemic gastroenteritis cases worldwide. The first open reading frame of the norovirus RNA genome encodes for a polyprotein that is cleaved by the viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162de73dd7e7ab6f7de2d06fb9be5139
https://eprints.soton.ac.uk/337340/
https://eprints.soton.ac.uk/337340/
KasA (β-Ketoacyl ACP synthase I) is involved in the biosynthetic pathway of mycolic acids, an essential component of the cell wall in Mycobacterium tuberculosis. It was shown that KasA is essential for the survival of the pathogen and thus could ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fa260ff38735ac2ff11b697addd295
https://europepmc.org/articles/PMC4397578/
https://europepmc.org/articles/PMC4397578/
Autor:
Kanishk Kapilashrami, Caroline Kisker, Gopal R. Bommineni, Peter J. Tonge, Bela P. Ruzsicska, Sylvia R. Luckner, Carl A. Machutta, Carlos Simmerling
Publikováno v:
The Journal of biological chemistry. 285(9)
Thiolactomycin (TLM), a natural product thiolactone antibiotic produced by species of Nocardia and Streptomyces, is an inhibitor of the beta-ketoacyl-acyl carrier protein synthase (KAS) enzymes in the bacterial fatty acid synthase pathway. Using enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6024168cd0b16c3217572ef2de9f890c
https://pubmed.ncbi.nlm.nih.gov/20018879
https://pubmed.ncbi.nlm.nih.gov/20018879
Autor:
Chris amEnde, Sylvia R. Luckner, Caroline Kisker, Peter J. Tonge, Hao Lu, Richard A. Slayden, Melissa E. Boyne
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa9071c641b51b2433e8c6046d763cdd
https://doi.org/10.1096/fasebj.22.1_supplement.791.6
https://doi.org/10.1096/fasebj.22.1_supplement.791.6
Publikováno v:
Journal of molecular biology. 368(3)
A 16-residue peptide, called Tip, induces the tetracycline repressor TetR as efficiently as the antibiotic tetracycline when fused to the N or C terminus of another protein. This is unusual because the majority of in vitro selected peptides, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbd4816381737eb45288fdf05a22274
https://pubmed.ncbi.nlm.nih.gov/17374541
https://pubmed.ncbi.nlm.nih.gov/17374541
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 70:C821-C821
Trichomoniasis is a common STD with an estimated prevalence of 4 million infections in the United States. The organism that causes trichomoniasis, Trichomonas vaginalis, is essentially anaerobic and contains proteins such as peroxidases that help det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a1fa9c979bdb449c4cc8120cfdee83d
https://doi.org/10.1107/s2053273314091785
https://doi.org/10.1107/s2053273314091785