Innate Immune Cell Suppression and the Link With Secondary Lung Bacterial Pneumonia

Autor: David J. Morgan, Joshua Casulli, Christine Chew, Emma Connolly, Sylvia Lui, Oliver J. Brand, Rizwana Rahman, Christopher Jagger, Tracy Hussell

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Secondary infections arise as a consequence of previous or concurrent conditions and occur in the community or in the hospital setting. The events allowing secondary infections to gain a foothold have been studied for many years and include poor nutr

Externí odkaz: https://doaj.org/article/c387a1735e69411d87e5f62f9e17df94

Detrimental effects of ethanol and its metabolite acetaldehyde, on first trimester human placental cell turnover and function.

Autor: Sylvia Lui, Rebecca L Jones, Nathalie J Robinson, Susan L Greenwood, John D Aplin, Clare L Tower

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e87328 (2014)

Fetal alcohol spectrum disorder (FASD) describes developmental issues from high maternal alcohol intake, which commonly results in fetal growth restriction and long term morbidity. We aimed to investigate the effect of alcohol and acetaldehyde, on th

Externí odkaz: https://doaj.org/article/de99283e9bfc4d2b88c849cf869b9cc9

Distribution and Function of Prostaglandin E2Receptors in Mouse Uterus: Translational Value for Human Reproduction

Autor: David F. Woodward, Peter O'Donovan, Anna L Griffiths, Deborah P Fischer, Uzmah J Sabar, Diane Farrar, Kay Marshall, Sylvia Lui

Publikováno v: Fischer, D P, Griffiths, A L, Lui, S, Sabar, U J, Farrar, D, O’donovan, P J, Woodward, D F & Marshall, K M 2020, ' Distribution and Function of Prostaglandin E 2 Receptors in Mouse Uterus: Translational Value for Human Reproduction ', Journal of Pharmacology and Experimental Therapeutics, vol. 373, no. 3, pp. 381-390 . https://doi.org/10.1124/jpet.119.263509

Prostaglandin (PG) E analogs are used clinically to ripen the cervix and induce labor. However, selective receptor agonists may have potential to improve induction response rates or manage unwanted uterine hypercontractility in conditions such as dys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31da3126689235ab7c100fbc4a599e3
https://doi.org/10.1124/jpet.119.263509

Alterations in T and B cell function persist in convalescent COVID-19 patients

Autor: Halima A. Shuwa, Tovah N. Shaw, Sean B. Knight, Kelly Wemyss, Flora A. McClure, Laurence Pearmain, Ian Prise, Christopher Jagger, David J. Morgan, Saba Khan, Oliver Brand, Elizabeth R. Mann, Andrew Ustianowski, Nawar Diar Bakerly, Paul Dark, Christopher E. Brightling, Seema Brij, Timothy Felton, Angela Simpson, John R. Grainger, Tracy Hussell, Joanne E. Konkel, Madhvi Menon, Rohan Ahmed, Miriam Avery, Katharine Birchall, Evelyn Charsley, Alistair Chenery, Christine Chew, Richard Clark, Emma Connolly, Karen Connolly, Simon Dawson, Laura Durrans, Hannah Durrington, Jasmine Egan, Kara Filbey, Claire Fox, Helen Francis, Miriam Franklin, Susannah Glasgow, Nicola Godfrey, Kathryn J. Gray, Seamus Grundy, Jacinta Guerin, Pamela Hackney, Chantelle Hayes, Emma Hardy, Jade Harris, Anu John, Bethany Jolly, Verena Kästele, Gina Kerry, Sylvia Lui, Lijing Lin, Alex G. Mathioudakis, Joanne Mitchell, Clare Moizer, Katrina Moore, Stuart Moss, Syed Murtuza Baker, Rob Oliver, Grace Padden, Christina Parkinson, Michael Phuycharoen, Ananya Saha, Barbora Salcman, Nicholas A. Scott, Seema Sharma, Jane Shaw, Joanne Shaw, Elizabeth Shepley, Lara Smith, Simon Stephan, Ruth Stephens, Gael Tavernier, Rhys Tudge, Louis Wareing, Roanna Warren, Thomas Williams, Lisa Willmore, Mehwish Younas

Publikováno v: Shuwa, H A, Shaw, T N, Knight, S B, Wemyss, K, McClure, F A, Pearmain, L, Prise, I, Jagger, C, Morgan, D J, Khan, S, Brand, O, Mann, E R, Ustianowski, A, Bakerly, N D, Dark, P, Brightling, C E, Brij, S, Felton, T, Simpson, A, Grainger, J R, Hussell, T, Konkel, J E & Menon, M 2021, ' Alterations in T and B cell function persist in convalescent COVID-19 patients ', Med, vol. 2, no. 6, pp. 720-735.E4 . https://doi.org/10.1016/j.medj.2021.03.013
Shuwa, H A, Shaw, T, Knight, S, Wemyss, K, Mcclure, F, Pearmain, L, Prise, I, Jagger, C, Morgan, D, Khan, S, Brand, O, Mann, E, Ustianowski, A, Diar Bakerly, N, Dark, P, Brightling, C E, Brij, S, Felton, T, Simpson, A, Grainger, J, Hussell, T, Konkel, J & Menon, M 2021, ' Alterations in T and B cell function persist in convalescent COVID-19 patients ', Med, vol. 2, no. 6, pp. 720-+ . https://doi.org/10.1016/j.medj.2021.03.013
Med (New York, N.y.)

Background Emerging studies indicate that some COVID-19 patients suffer from persistent symptoms including breathlessness and chronic fatigue; however the long-term immune response in these patients presently remains ill-defined. Methods Here we desc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b67c5628225813d3ceef6415c87a6c6
https://hdl.handle.net/20.500.11820/bb6608a9-a1e2-4f82-b861-0aceac9047c9

Distribution and Function of Prostaglandin E

Autor: Deborah P, Fischer, Anna L, Griffiths, Sylvia, Lui, Uzmah J, Sabar, Diane, Farrar, Peter J, O'Donovan, David F, Woodward, Kay M, Marshall

Publikováno v: The Journal of pharmacology and experimental therapeutics. 373(3)

Prostaglandin (PG) E analogs are used clinically to ripen the cervix and induce labor. However, selective receptor agonists may have potential to improve induction response rates or manage unwanted uterine hypercontractility in conditions such as dys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e32a5c363830bb45776c4ac758752f76
https://pubmed.ncbi.nlm.nih.gov/32205366