Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sylvia Kwan"'
Autor:
Jonathan M. Gilbert, Sandra Zurawski, Theresa Clifford, Ted T. Kung, Stephen D. Hurst, Sylvia Kwan, Craig Jackson, Brian W. P. Seymour, Tony Muchamuel, Satish Menon, Gerard Zurawski, Joan K. Brieland, Daniel M. Gorman, Richard W. Chapman, Robert L. Coffman
Publikováno v:
The Journal of Immunology. 169:443-453
We have biologically characterized two new members of the IL-17 cytokine family: IL-17F and IL-25. In contrast to conventional in vitro screening approaches, we have characterized the activity of these new molecules by direct in vivo analysis and hav
Autor:
Anna Vu, Laurence Fayadat-Dilman, Kyu Hong, Cheng-Chi Chao, Nicole Davis, Agelio Asio, Iannis E. Adamopoulos, Shi-Juan Chen, Sylvia Kwan, Edward P. Bowman
Publikováno v:
Autoimmunity. 44(3)
Interleukin-17A (IL-17A) is a pro-inflammatory cytokine secreted by a subset of memory T cells and other innate immune cells. It is associated with rheumatoid arthritis (RA) due to IL-17A expression in RA synovial fluid. The severe bone erosive rat a
Autor:
Jonathan P Sherlock, Sylvia Kwan, Sandra Zurawski, Brian W. P. Seymour, Yi Chen, Daniel J. Cua, Wayne To, Jonathon D. Sedgwick, Tatyana Churakova, Maria T. Wiekowski, Robert A. Kastelein, Barbara L. Joyce, Linda Lucian, Craig A. Murphy, Sergio A. Lira, Daniel M. Gorman
Publikováno v:
Nature. 421(6924)
Interleukin-12 (IL-12) is a heterodimeric molecule composed of p35 and p40 subunits. Analyses in vitro have defined IL-12 as an important factor for the differentiation of naive T cells into T-helper type 1 CD4+ lymphocytes secreting interferon-gamma