Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sylvia Kerschbaum-Gruber"'
Autor:
Sylvia Kerschbaum-Gruber, Ava Kleinwächter, Katerina Popova, Alexandra Kneringer, Lisa-Marie Appel, Katharina Stasny, Anna Röhrer, Ana Beatriz Dias, Johannes Benedum, Lena Walch, Andreas Postl, Sandra Barna, Bernhard Kratzer, Winfried F. Pickl, Altuna Akalin, Filip Horvat, Vedran Franke, Joachim Widder, Dietmar Georg, Dea Slade
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer-related deaths worldwide with limited treatment options due to extensive radiation and chemotherapy resistance. Monotherapy with immune checkpoint blockade showed n
Externí odkaz:
https://doaj.org/article/3025e223cab047d6828e139b1e21af01
Autor:
Maximilian Schmid, Patrick Fischer, Magdalena Engl, Joachim Widder, Sylvia Kerschbaum-Gruber, Dea Slade
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Autophagy is an intracellular process that targets various cargos for degradation, including members of the cGAS-STING signaling cascade. cGAS-STING senses cytosolic double-stranded DNA and triggers an innate immune response through type I interferon
Externí odkaz:
https://doaj.org/article/e33cc8e2da4246ad9790ec9b304dbb15
Autor:
Sylvia Kerschbaum-Gruber, Fatima Padilla-Cabal, Elisabeth Mara, Birgit Lohberger, Dietmar Georg, Hermann Fuchs
Publikováno v:
Zeitschrift für Medizinische Physik, Vol 32, Iss 3, Pp 326-333 (2022)
Background and purpose: Magnetic field effects on the radiobiological effectiveness during treatment of magnetic resonance (MRI) guided particle therapy are being debated. This study aims at assessing the influence of a perpendicular magnetic field o
Externí odkaz:
https://doaj.org/article/99f58db5d2694bb79e2ce6e138cde268
Autor:
Simon Deycmar, Elisabeth Mara, Sylvia Kerschbaum-Gruber, Verena Waller, Dietmar Georg, Martin Pruschy
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-17 (2022)
Abstract Objective Hypersensitivity towards proton versus photon irradiation was demonstrated in homologous recombination repair (HRR)-deficient cell lines. Hence, combined treatment concepts targeting HRR provide a rational for potential pharmaceuti
Externí odkaz:
https://doaj.org/article/5e7e5ab9a4b44a9eb88a9cbed686867f
Autor:
Birgit Lohberger, Dietmar Glänzer, Nicole Eck, Sylvia Kerschbaum-Gruber, Elisabeth Mara, Simon Deycmar, Tobias Madl, Karl Kashofer, Petra Georg, Andreas Leithner, Dietmar Georg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Although particle therapy with protons has proven to be beneficial in the treatment of chondrosarcoma compared to photon-based (X-ray) radiation therapy, the cellular and molecular mechanisms have not yet been sufficiently investigated. Cell
Externí odkaz:
https://doaj.org/article/c249fa5290854629a486e51aa2fe0509
Autor:
Birgit Lohberger, Sandra Barna, Dietmar Glänzer, Nicole Eck, Sylvia Kerschbaum-Gruber, Katharina Stasny, Andreas Leithner, Dietmar Georg
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11464
Chondrosarcomas are particularly difficult to treat due to their resistance to chemotherapy and radiotherapy. However, particle therapy can enhance local control and patient survival rates. To improve our understanding of the basic cellular radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4180ce700e0bd1b91e4bbd65946cfa9d
https://pubmed.ncbi.nlm.nih.gov/36232764
https://pubmed.ncbi.nlm.nih.gov/36232764
Autor:
Sylvia Kerschbaum-Gruber, Fatima Padilla-Cabal, Elisabeth Mara, Birgit Lohberger, Dietmar Georg, Hermann Fuchs
Publikováno v:
Zeitschrift fur medizinische Physik. 32(3)
Magnetic field effects on the radiobiological effectiveness during treatment of magnetic resonance (MRI) guided particle therapy are being debated. This study aims at assessing the influence of a perpendicular magnetic field on the biological effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7430217b0000cb6542f5e9140a7824
https://pubmed.ncbi.nlm.nih.gov/35058110
https://pubmed.ncbi.nlm.nih.gov/35058110
Autor:
Nicole Eck, Dietmar Georg, Sylvia Kerschbaum-Gruber, Andreas Leithner, Dietmar Glaenzer, Birgit Lohberger, Beate Rinner, Bibiane Steinecker-Frohnwieser
Publikováno v:
Oncology Letters
Chondrosarcomas represent a heterogeneous group of primary bone cancers that are characterized by hyaline cartilaginous neoplastic tissue and are predominantly resistant to radiation and chemotherapy. However, adjuvant radiotherapy is often recommend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4815fc73abe30f4e4d9972c2994adb
https://pubmed.ncbi.nlm.nih.gov/33868466
https://pubmed.ncbi.nlm.nih.gov/33868466