Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Sylvia K. Plevritis"'
Autor:
Nancy Yanzhe Li, Weiruo Zhang, Daniel Haensel, Anna R. Jussila, Cory Pan, Sadhana Gaddam, Sylvia K. Plevritis, Anthony E. Oro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Cancer-associated inflammation is a double-edged sword possessing both pro- and anti-tumor properties through ill-defined tumor-immune dynamics. While we previously identified a carcinoma tumor-intrinsic resistance pathway, basal-to-squamous
Externí odkaz:
https://doaj.org/article/88d555228c794b15a0303b41ed1d8731
Autor:
Loukia G. Karacosta, Danny Pancirer, Jordan S. Preiss, Jalen A. Benson, Winston Trope, Joseph B. Shrager, Arthur Wai Sung, Joel W. Neal, Sean C. Bendall, Heather Wakelee, Sylvia K. Plevritis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Malignant pleural effusions (MPEs) can be utilized as liquid biopsy for phenotyping malignant cells and for precision immunotherapy, yet MPEs are inadequately studied at the single-cell proteomic level. Here we leverage mass cytometry to int
Externí odkaz:
https://doaj.org/article/d8612f1f48db4c5a98c79cd070079b2b
Autor:
Kevin Brennan, Almudena Espín-Pérez, Serena Chang, Nikita Bedi, Saumyaa Saumyaa, June Ho Shin, Sylvia K. Plevritis, Olivier Gevaert, John B. Sunwoo, Andrew J. Gentles
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-26 (2023)
Abstract Background The prognosis for patients with head and neck cancer (HNC) is poor and has improved little in recent decades, partially due to lack of therapeutic options. To identify effective therapeutic targets, we sought to identify molecular
Externí odkaz:
https://doaj.org/article/64cfbc02ed7142e4ba40972bf22f174f
Autor:
Yapeng Su, Melissa E. Ko, Hanjun Cheng, Ronghui Zhu, Min Xue, Jessica Wang, Jihoon W. Lee, Luke Frankiw, Alexander Xu, Stephanie Wong, Lidia Robert, Kaitlyn Takata, Dan Yuan, Yue Lu, Sui Huang, Antoni Ribas, Raphael Levine, Garry P. Nolan, Wei Wei, Sylvia K. Plevritis, Guideng Li, David Baltimore, James R. Heath
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Detailed understanding of how cancer cells transition from a drug sensitive to a tolerant state is lacking. Here, using single cell proteomic and metabolic data the authors uncover that isogenic BRAF mutant melanoma cells can take two distinct paths
Externí odkaz:
https://doaj.org/article/ef83fd0a40a640fbb4a0b6caefb26789
Autor:
Andrew J. Gentles, Angela Bik-Yu Hui, Weiguo Feng, Armon Azizi, Ramesh V. Nair, Gina Bouchard, David A. Knowles, Alice Yu, Youngtae Jeong, Alborz Bejnood, Erna Forgó, Sushama Varma, Yue Xu, Amanda Kuong, Viswam S. Nair, Rob West, Matt van de Rijn, Chuong D. Hoang, Maximilian Diehn, Sylvia K. Plevritis
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-22 (2020)
Abstract Background Tumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and
Externí odkaz:
https://doaj.org/article/cc0f2098680f4d72b3ab8a49201dc29f
Autor:
Loukia G. Karacosta, Benedict Anchang, Nikolaos Ignatiadis, Samuel C. Kimmey, Jalen A. Benson, Joseph B. Shrager, Robert Tibshirani, Sean C. Bendall, Sylvia K. Plevritis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Intermediate transitions between epithelial and mesenchymal states are associated with tumor progression. Here using mass cytometry, Plevritis and colleagues develop a computational framework to resolve and map these trajectories in lung cancer cells
Externí odkaz:
https://doaj.org/article/32513de8c44b402d8bbb56fe5705714c
Autor:
Iakovos Toumazis, Pianpian Cao, Koen de Nijs, Mehrad Bastani, Vidit Munshi, Mehdi Hemmati, Kevin ten Haaf, Jihyoun Jeon, Martin Tammemägi, G. Scott Gazelle, Eric J. Feuer, Chung Yin Kong, Rafael Meza, Harry J. de Koning, Sylvia K. Plevritis, Summer S. Han
Publikováno v:
Annals of Internal Medicine, 176(3), 320-332. American College of Physicians
Background: In their 2021 lung cancer screening recommendation update, the U.S. Preventive Services Task Force (USPSTF) evaluated strategies that select people based on their personal lung cancer risk (risk model–based strategies), highlighting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d487716cb7d5e1b04d0f7aeba8ddad
https://doi.org/10.7326/m22-2216
https://doi.org/10.7326/m22-2216
Autor:
Zinaida Good, Jay Y. Spiegel, Bita Sahaf, Meena B. Malipatlolla, Zach J. Ehlinger, Sreevidya Kurra, Moksha H. Desai, Warren D. Reynolds, Anita Wong Lin, Panayiotis Vandris, Fang Wu, Snehit Prabhu, Mark P. Hamilton, John S. Tamaresis, Paul J. Hanson, Shabnum Patel, Steven A. Feldman, Matthew J. Frank, John H. Baird, Lori Muffly, Gursharan K. Claire, Juliana Craig, Katherine A. Kong, Dhananjay Wagh, John Coller, Sean C. Bendall, Robert J. Tibshirani, Sylvia K. Plevritis, David B. Miklos, Crystal L. Mackall
Publikováno v:
Nature Medicine. 28:1860-1871
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a284073da540a5e330f056d140435715
https://doi.org/10.1038/s41591-022-01960-7
https://doi.org/10.1038/s41591-022-01960-7
Autor:
Parag Mallick, David B. Agus, Samir Hanash, Anjali Jain, Martin W. McIntosh, Sylvia K. Plevritis, Mitchell E. Gross, Jonathan E. Katz, Qing Zhang, Sharon J. Pitteri, Joanna Schmidt, Jonathan Erde, Roland Luethy, Babak Shahbaba, Qiaojun Fang, Wenxuan Zhang, Lindsey D. Hughes, Vitor M. Faca, Kian Kani
PDF file, 5465KB, Quantitation tables for proteins identified and quantified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed0632734ae224ff44e6e50ca82ec32
https://doi.org/10.1158/1535-7163.22499257
https://doi.org/10.1158/1535-7163.22499257
Autor:
Parag Mallick, David B. Agus, Samir Hanash, Anjali Jain, Martin W. McIntosh, Sylvia K. Plevritis, Mitchell E. Gross, Jonathan E. Katz, Qing Zhang, Sharon J. Pitteri, Joanna Schmidt, Jonathan Erde, Roland Luethy, Babak Shahbaba, Qiaojun Fang, Wenxuan Zhang, Lindsey D. Hughes, Vitor M. Faca, Kian Kani
PDF file, 3.66MB, Proteomic data table. Tabular list of proteomic data from the 2 hr and 16 hour gefitinib treated experiments. Whole cell lysate (WCL), cell-surface (SUR), and SPEG/GC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c6d439673b8df7e4940ce91612cc1c
https://doi.org/10.1158/1535-7163.22499260
https://doi.org/10.1158/1535-7163.22499260