Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sylvia J Wowro"'
Autor:
Chen Li, Marie F. Kiefer, Sarah Dittrich, Roberto E. Flores, Yueming Meng, Na Yang, Sascha Wulff, Sabrina Gohlke, Manuela Sommerfeld, Sylvia J. Wowro, Konstantin M. Petricek, Dominic Dürbeck, Leonard Spranger, Knut Mai, Holger Scholz, Tim J. Schulz, Michael Schupp
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101855- (2024)
Objective: Retinol saturase (RetSat) is an endoplasmic reticulum-localized oxidoreductase highly expressed in organs involved in lipid metabolism such as white (WAT) and brown adipose tissue (BAT). Cold exposure was shown to increase RETSAT protein i
Externí odkaz:
https://doaj.org/article/f18b3210ab99484c8d43d3ad761df1c5
Autor:
Linda van den Berg, Krista Kokki, Sylvia J. Wowro, Konstantin M. Petricek, Onur Deniz, Catrin A. Stegmann, Marius Robciuc, Mari Teesalu, Richard G. Melvin, Anni I. Nieminen, Michael Schupp, Ville Hietakangas
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112739- (2023)
Summary: The ability to feed on a sugar-containing diet depends on a gene regulatory network controlled by the intracellular sugar sensor Mondo/ChREBP-Mlx, which remains insufficiently characterized. Here, we present a genome-wide temporal clustering
Externí odkaz:
https://doaj.org/article/65971c572d3b492db9e0387223bacef0
Autor:
Julia S. Steinhoff, Carina Wagner, Ulrike Taschler, Sascha Wulff, Marie F. Kiefer, Konstantin M. Petricek, Sylvia J. Wowro, Moritz Oster, Roberto E. Flores, Na Yang, Chen Li, Yueming Meng, Manuela Sommerfeld, Stefan Weger, Andrea Henze, Jens Raila, Achim Lass, Michael Schupp
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 10, Pp 100268- (2022)
Hepatocytes secrete retinol-binding protein 4 (RBP4) into circulation, thereby mobilizing vitamin A from the liver to provide retinol for extrahepatic tissues. Obesity and insulin resistance are associated with elevated RBP4 levels in the blood. Howe
Externí odkaz:
https://doaj.org/article/3e03abb6a7e44542a7029ef73356845c
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Objective. Cold-inducible RNA-binding protein (CIRBP) has been shown to be involved not only in cooling-induced cellular protection but also as a mediator of sterile inflammation, a critical mechanism of the innate immune response in ischemia/reperfu
Externí odkaz:
https://doaj.org/article/6f27a4bb33ed4dfe83080acb1a7df2b0
Autor:
Giang Tong, Phuong D. Lam, Franka Brey, Jana Krech, Sylvia J. Wowro, Nalina N. A. von Garlen, Felix Berger, Katharina R. L. Schmitt
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Introduction. Ischemia/Reperfusion (I/R) is a primary cause of myocardial injury after acute myocardial infarction resulting in the release of damage-associated molecular patterns (DAMPs), which can induce a sterile inflammatory response in the myoca
Externí odkaz:
https://doaj.org/article/c563222c3d3b43d3a82383bc7964116b
Autor:
Annabell Plauth, Anne Geikowski, Susanne Cichon, Sylvia J. Wowro, Linda Liedgens, Morten Rousseau, Christopher Weidner, Luise Fuhr, Magdalena Kliem, Gail Jenkins, Silvina Lotito, Linda J. Wainwright, Sascha Sauer
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 433-437 (2016)
We show here if under physiologically relevant conditions resveratrol (RSV) remains stable or not. We further show under which circumstances various oxidation products of RSV such as ROS can be produced. For example, in addition to the widely known e
Externí odkaz:
https://doaj.org/article/76504a6b8f29466a9f6895f328d328dc
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
IntroductionHypothermia attenuates cerebral ischemia-induced neuronal cell death associated with neuroinflammation. The calcineurin inhibitor cyclosporin A (CsA) has been shown to be neuroprotective by minimizing activation of inflammatory pathways.
Externí odkaz:
https://doaj.org/article/0fd238ecb7d84ea6a76601e4a7156f20
Autor:
Giang Tong, Nalina N. A. von Garlen, Sylvia J. Wowro, Phuong D. Lam, Jana Krech, Felix Berger, Katharina R. L. Schmitt
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexi
Externí odkaz:
https://doaj.org/article/dd3e6aeca3ab4583ba9341f2171b3955
Autor:
Christopher Weidner, Morten Rousseau, Annabell Plauth, Sylvia J Wowro, Cornelius Fischer, Heba Abdel-Aziz, Sascha Sauer
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152398 (2016)
Massively increasing global incidences of colorectal cancer require efficient treatment and prevention strategies. Here, we report unexpected anticancerogenic effects of hydroethanolic Iberis amara extract (IAE), which is known as a widely used phyto
Externí odkaz:
https://doaj.org/article/d857bc33ff9b4b939ce21f02bf533abd
Autor:
Katharina Rose Luise Schmitt, Felix Berger, Sylvia J. Wowro, Constanze Pfitzer, Giang Tong, Wolfgang Böttcher, Lisa-Maria Rosenthal, Oliver Miera, Christoph Walker
Publikováno v:
Therapeutic Hypothermia and Temperature Management. 10:60-70
Therapeutic hypothermia during cardiac surgery has been widely used for neuroprotection and to attenuate the systemic inflammatory response due to cardiopulmonary bypass (CPB). Experimental data suggest that cold-shock protein RNA-binding motif 3 (RB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f922002c50d682c9406850992c1445d
https://doi.org/10.1089/ther.2018.0038
https://doi.org/10.1089/ther.2018.0038