Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sylvia Hilliard"'
Autor:
Fabiola Diniz, Nguyen Yen Nhi Ngo, Mariel Colon-Leyva, Francesca Edgington-Giordano, Sylvia Hilliard, Kevin Zwezdaryk, Jiao Liu, Samir S. El-Dahr, Giovane G. Tortelote
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Nephron endowment at birth impacts long-term renal and cardiovascular health, and it is contingent on the nephron progenitor cell (NPC) pool. Glycolysis modulation is essential for determining NPC fate, but the underlying mechanism is unclea
Externí odkaz:
https://doaj.org/article/23ad3644edca43628130dae686ae3d97
Autor:
Sylvia Hilliard, Renfang Song, Hongbing Liu, Chao-hui Chen, Yuwen Li, Melody Baddoo, Erik Flemington, Alanna Wanek, Jay Kolls, Zubaida Saifudeen, Samir S. El-Dahr
Publikováno v:
Biology Open, Vol 8, Iss 5 (2019)
Six2+ cap mesenchyme cells, also called nephron progenitor cells (NPC), are precursors of all epithelial cell types of the nephron, the filtering unit of the kidney. Current evidence indicates that perinatal ‘old’ NPC have a greater tendency to e
Externí odkaz:
https://doaj.org/article/0cd0ec4a59ae40ed910bd19e03746fd7
Autor:
Eman A Toraih, Emmanuelle Ruiz, Bo Ning, Giovane G Tortelote, Sylvia Hilliard, Krzysztof Moroz, Tony Hu, Manal S Fawzy, Emad Kandil
Publikováno v:
Journal of the American College of Surgeons. 236:732-750
Autor:
Eman A. Toraih, Manal S. Fawzy, Bo Ning, Mourad Zerfaoui, Youssef Errami, Emmanuelle M. Ruiz, Mohammad H. Hussein, Muhib Haidari, Melyssa Bratton, Giovane G. Tortelote, Sylvia Hilliard, Naris Nilubol, Jonathon O. Russell, Mohamed A. Shama, Samir S. El-Dahr, Krzysztof Moroz, Tony Hu, Emad Kandil
Publikováno v:
Cancers; Volume 14; Issue 17; Pages: 4128
Papillary thyroid carcinomas (PTCs) account for most endocrine tumors; however, screening and diagnosing the recurrence of PTC remains a clinical challenge. Using microRNA sequencing (miR-seq) to explore miRNA expression profiles in PTC tissues and a
Autor:
Samir S. El-Dahr, Zubaida Saifudeen, Sylvia Hilliard, Chao-Hui Chen, Elizabeth Kelly, Hongbing Liu
Publikováno v:
J Biol Chem
SIX2 (SIX homeobox 2)–positive nephron progenitor cells (NPCs) give rise to all epithelial cell types of the nephron, the filtering unit of the kidney. NPCs have a limited lifespan and are depleted near the time of birth. Epigenetic factors are imp
Autor:
Hongbing, Liu, Nguyen Yen Nhi, Ngo, Kyra F, Herzberger, Manasi, Gummaraju, Sylvia, Hilliard, Chao-Hui, Chen
Publikováno v:
Biochemical Pharmacology. 206:115341
Our studies demonstrated the critical role of Histone deacetylases (HDACs) in the regulation of nephrogenesis. To better understand the key pathways regulated by HDAC1/2 in early nephrogenesis, we performed chromatin immunoprecipitation sequencing (C
Publikováno v:
J Am Soc Nephrol
STRUCTURED ABSTRACTBackgroundCis-regulatory elements (CREs), such as enhancers and promoters, and their cognate transcription factors play a central role in cell fate specification. Bulk analysis of CREs has provided insights into gene regulation in
Publikováno v:
Journal of Molecular Cell Biology
While p53 activity is required for tumour suppression, unconstrained p53 activity on the other hand is detrimental to the organism, resulting in inappropriate cellular death or proliferation defects. Unimpeded p53 activity is lethal in the developing
Publikováno v:
Mech Dev
The antagonism between Mdm2 and its close homolog Mdm4 (also known as MdmX) and p53 is vital for embryogenesis and organogenesis. Previously, we demonstrated that targeted disruption of Mdm2 in the Hoxb7+ ureteric bud (Ub) lineage, which gives rise t
Autor:
Yuwen Li, Sylvia Hilliard, Chao-Hui Chen, Jay K. Kolls, Alanna Wanek, Melody Baddoo, Hongbing Liu, Renfang Song, Erik K. Flemington, Zubaida Saifudeen, Samir S. El-Dahr
Six2+ cap mesenchyme cells, also called nephrons progenitor cells (NPC), are precursors of all epithelial cell types of the nephron, the filtering unit of the kidney. Current evidence indicates that perinatal “old” NPC have a greater tendency to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff82d3fb2c589944cc0e2a155458d0b