Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Sylvia Feyler"'
Autor:
Jonathan Carmichael, Frances Seymour, Graham McIlroy, Sarrah Tayabali, Rosie Amerikanou, Sylvia Feyler, Rakesh Popat, Guy Pratt, Christopher Parrish, A. John Ashcroft, Graham H. Jackson, Gordon Cook
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are especially susceptible to poor outcomes. However, even for MM patients
Externí odkaz:
https://doaj.org/article/4261423c0dbc42d4ae909538097e3338
Autor:
Gareth J. Morgan, Faith E. Davies, Walter M. Gregory, Sue E. Bell, Alexander J. Szubert, Nuria Navarro Coy, Gordon Cook, Sylvia Feyler, Peter R.E. Johnson, Claudius Rudin, Mark T. Drayson, Roger G. Owen, Fiona M. Ross, Nigel H. Russell, Graham H. Jackson, J. Anthony Child
Publikováno v:
Haematologica, Vol 97, Iss 3 (2012)
Background Thalidomide is active in multiple myeloma and is associated with minimal myelosuppression, making it a good candidate for induction therapy prior to high-dose therapy with autologous stem-cell transplantation.Design and Methods Oral cyclop
Externí odkaz:
https://doaj.org/article/041499dacc9f47dd98b2ea06bd51cabf
Autor:
Sylvia Feyler, Gina B Scott, Christopher Parrish, Sarah Jarmin, Paul Evans, Mike Short, Katherine McKinley, Peter J Selby, Gordon Cook
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35981 (2012)
Regulatory T-cells (T(Reg) cells) are increased in patients with multiple myeloma (MM). We investigated whether MM cells could generate and/or expand T(Reg) cells as a method of immuno-surveillance avoidance. In an in vitro model, CD4(+)CD25(-)FoxP3(
Externí odkaz:
https://doaj.org/article/7ab97c00f5c94b90a75c5d895e4866b7
Autor:
Jonathan Carmichael, Frances Seymour, Graham Mcilroy, Sarrah Tayabali, Rodothea Amerikanou, Sylvia Feyler, June Aung, Rakesh Popat, Guy Pratt, Christopher Parrish, John Ashcroft, Graham Jackson, Gordon Cook
The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are es-pecially susceptible to poor outcomes. However, even for MM patients who avo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f000509d0ab02e144eb3166ffa13d9d
https://doi.org/10.21203/rs.3.rs-2230271/v1
https://doi.org/10.21203/rs.3.rs-2230271/v1
Autor:
Sue E. Bell, AJ Szubert, Kevin Boyd, Walter M Gregory, Sylvia Feyler, Claudius Rudin, Gareth J. Morgan, Roger G. Owen, Nuria Navarro Coy, Mark T. Drayson, Graham Jackson, Jennifer Byrne, A J Ashcroft, Faith E. Davies, Huw Roddie, J. Anthony Child, Gordon Cook, Fiona M. Ross, Wendy Osborne, Ping Wu
Publikováno v:
British Journal of Haematology. 166:109-117
Bisphosphonates are recommended in patients with osteolytic lesions secondary to multiple myeloma. We report on the safety of bisphosphonate therapy with long-term follow-up in the Medical Research Council Myeloma IX study. Patients with newly diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2200625e5bed0293faf8c0faaf6d79b8
https://doi.org/10.1111/bjh.12861
https://doi.org/10.1111/bjh.12861
Publikováno v:
Blood Reviews. 27:155-164
An effective immune response requires a prompt but measured action against the pathological insult, to prevent over-zealous inflammatory-mediated tissue destruction. In cancer, defective or incompetent immune responses may paradoxically result in dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82e9cdb1756cce2fa4724c4246f272b
https://doi.org/10.1016/j.blre.2013.04.004
https://doi.org/10.1016/j.blre.2013.04.004
Autor:
Sylvia Feyler, Eric Low, Guy Pratt, John A. Snowden, Gordon Cook, UK Myeloma Forum, Roger G. Owen, Jennifer M. Bird, Jamie Cavenagh, Gareth J. Morgan, Kwee Yong, John Ashcroft, Faith E. Davies, Shirley D'Sa, Judith Behrens
Publikováno v:
British Journal of Haematology. 154:32-75
653. Spencer, A., Prince, H.M., Roberts, A.W., Prosser, I.W., Bradstock, K.F., Coyle, L., Gill, D.S., Horvath, N., Reynolds, J. & Kennedy, N. (2009) Consolidation therapy with low-dose thalido- mide and prednisolone prolongs the survival of multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3dad56352b548e406d5ab0b8187a16
https://doi.org/10.1111/j.1365-2141.2011.08573.x
https://doi.org/10.1111/j.1365-2141.2011.08573.x
Autor:
Eric Low, Shirley D'Sa, Rhona Maclean, Timothy Littlewood, Jennifer M. Bird, Sylvia Feyler, H Lucraft, Sam H Ahmedzai, John A. Snowden, Guy Pratt, John Ashcroft, UK Myeloma Forum
Publikováno v:
British Journal of Haematology. 154:76-103
Supportive care plays an increasingly important role in the modern management of multiple myeloma. While modern treatments have significantly prolonged overall and progression free survival through improved disease control, the vast majority of patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e0cc4fc92c7afee715bf6259771926
https://doi.org/10.1111/j.1365-2141.2011.08574.x
https://doi.org/10.1111/j.1365-2141.2011.08574.x
Autor:
Fiona M. Ross, Graham Jackson, Sylvia Feyler, Mark T. Drayson, Kim Cocks, Walter M Gregory, Jennifer Byrne, Alex J Szubert, Gareth J. Morgan, Faith E. Davies, Sue E. Bell, J. Anthony Child, A John Ashcroft, Nuria Navarro-Coy, Gordon Cook, Huw Roddie, Claudius Rudin, Roger G. Owen
Publikováno v:
The Lancet. 376:1989-1999
Summary Background Bisphosphonates reduce the risk of skeletal events in patients with malignant bone disease, and zoledronic acid has shown potential anticancer effects in preclinical and clinical studies. We aimed to establish whether bisphosphonat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde8a8d8d52eabbdd6e0e2790a0bc18a
https://doi.org/10.1016/s0140-6736(10)62051-x
https://doi.org/10.1016/s0140-6736(10)62051-x
Autor:
Marie von Lilienfeld-Toal, Sylvia Feyler, Roger G. Owen, Sarah Jarmin, A J Ashcroft, Peter Selby, Lee Marles, Andy C. Rawstron, Gordon Cook
Publikováno v:
British Journal of Haematology. 144:686-695
Increased levels of naturally occurring regulatory T cells (T(Reg) cells) have been found in a variety of solid tumours and haematological malignancies. In multiple myeloma (MM), evidence suggests that T(Reg) cells are increased though controversy ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39cc04598d25c5b53e4cec6970051cf1
https://doi.org/10.1111/j.1365-2141.2008.07530.x
https://doi.org/10.1111/j.1365-2141.2008.07530.x