Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sylvia E J Fischer"'
Bacteria are a major determinant of Orsay virus transmission and infection in Caenorhabditis elegans
Publikováno v:
eLife, Vol 12 (2024)
The microbiota is a key determinant of the physiology and immunity of animal hosts. The factors governing the transmissibility of viruses between susceptible hosts are incompletely understood. Bacteria serve as food for Caenorhabditis elegans and rep
Externí odkaz:
https://doaj.org/article/095f34fede404b8c95db1b7b66fcf9be
Autor:
Taiowa A Montgomery, Young-Soo Rim, Chi Zhang, Robert H Dowen, Carolyn M Phillips, Sylvia E J Fischer, Gary Ruvkun
Publikováno v:
PLoS Genetics, Vol 8, Iss 4, p e1002616 (2012)
Small RNAs--including piRNAs, miRNAs, and endogenous siRNAs--bind Argonaute proteins to form RNA silencing complexes that target coding genes, transposons, and aberrant RNAs. To assess the requirements for endogenous siRNA formation and activity in C
Externí odkaz:
https://doaj.org/article/fb8ab92b94564be8b53cf0be267f40b2
Autor:
Sylvia E J Fischer, Taiowa A Montgomery, Chi Zhang, Noah Fahlgren, Peter C Breen, Alexia Hwang, Christopher M Sullivan, James C Carrington, Gary Ruvkun
Publikováno v:
PLoS Genetics, Vol 7, Iss 11, p e1002369 (2011)
Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segregation; however, the specific
Externí odkaz:
https://doaj.org/article/51e9ea26caa74dd09c4adc58ba7a5093
Autor:
Paola Sebastiani, Monty Montano, Annibale Puca, Nadia Solovieff, Toshio Kojima, Meng C Wang, Efthymia Melista, Micah Meltzer, Sylvia E J Fischer, Stacy Andersen, Stephen H Hartley, Amanda Sedgewick, Yasumichi Arai, Aviv Bergman, Nir Barzilai, Dellara F Terry, Alberto Riva, Chiara Viviani Anselmi, Alberto Malovini, Aya Kitamoto, Motoji Sawabe, Tomio Arai, Yasuyuki Gondo, Martin H Steinberg, Nobuyoshi Hirose, Gil Atzmon, Gary Ruvkun, Clinton T Baldwin, Thomas T Perls
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8210 (2009)
The strong familiality of living to extreme ages suggests that human longevity is genetically regulated. The majority of genes found thus far to be associated with longevity primarily function in lipoprotein metabolism and insulin/IGF-1 signaling. Th
Externí odkaz:
https://doaj.org/article/fa7f218462b9403da2649f61a12fb2b8
Autor:
Maya, Braun, Shachar, Shoshani, Joana, Teixeira, Anna, Mellul Shtern, Maya, Miller, Zvi, Granot, Sylvia E J, Fischer, Susana M D A, Garcia, Yuval, Tabach
Publikováno v:
iScience. 25(5)
Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases and cause RNA toxicity and multisystemic symptoms that worsen with age. Through an unclear mechanism, RNA toxicity can trigger severe disease manifestation in infants i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80384c67742ed93f9d605d9ba66d6ba3
https://pubmed.ncbi.nlm.nih.gov/35494247
https://pubmed.ncbi.nlm.nih.gov/35494247
Autor:
Sylvia E. J. Fischer, Maya Braun, Maya Miller, Z. Granot, Yuval Tabach, S. Shoshani, Susana M. D. A. Garcia, J. Teixeira, A. Mellul-Shtern
Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases. These repeats cause RNA toxicity and trigger multisystemic symptoms that worsen with age. RNA toxicity can trigger, through an unclear mechanism, severe disease manife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced74da24b80dce3d86bac384c223f96
https://doi.org/10.1101/2021.05.19.444826
https://doi.org/10.1101/2021.05.19.444826
Autor:
Abdul Rouf Dar, Rebecca A. Butcher, Susan E. Mango, Jon Clardy, Sylvia E. J. Fischer, Sabine Keppler-Ross, Konstantinos Kagias, Jadiel A. Wasson, Trisha J. Brock, Gareth Harris, Yun Zhang
Mothers contribute cytoplasmic components to their progeny in a process called maternal provisioning. Provisioning is influenced by the parental environment, but the molecular pathways that transmit environmental cues from mother to progeny are not w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4fed36a4e1e3c6ff5e22bfb3eaca5ea
https://doi.org/10.1101/2021.02.01.429208
https://doi.org/10.1101/2021.02.01.429208
Autor:
Jadiel A, Wasson, Gareth, Harris, Sabine, Keppler-Ross, Trisha J, Brock, Abdul R, Dar, Rebecca A, Butcher, Sylvia E J, Fischer, Konstantinos, Kagias, Jon, Clardy, Yun, Zhang, Susan E, Mango
Publikováno v:
Science Advances
Neuronal FMRFamide signaling transmits social cues to modulate maternal provisioning of translational machinery.
Mothers contribute cytoplasmic components to their progeny in a process called maternal provisioning. Provisioning is influenced by
Mothers contribute cytoplasmic components to their progeny in a process called maternal provisioning. Provisioning is influenced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f25cfb0944848aac3784e3bfc81ef8e
https://pubmed.ncbi.nlm.nih.gov/34417172
https://pubmed.ncbi.nlm.nih.gov/34417172
Autor:
Anthony Anselmo, Gary Ruvkun, Ruslan I. Sadreyev, Sylvia E. J. Fischer, Fei Ji, Martin A. Newman
Publikováno v:
Genes & Development. 32:670-681
RNAi pathways detect and silence foreign nucleic acids such as viruses as well as endogenous genes in many species. The phylogenetic profile across eukaryotes of proteins that mediate key steps in RNAi is correlated with the profiles of multiple mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81aeff6308caf7dab09094c6a6ab4b5a
https://doi.org/10.1101/gad.311514.118
https://doi.org/10.1101/gad.311514.118
Autor:
Sylvia E. J. Fischer, Gary Ruvkun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Silencing of transposable elements and viruses is critical for the maintenance of genome integrity, cellular homeostasis, and organismal health. Here we describe multiple factors that control different types of transposable elements, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b827c14fed7392ee6732b9cf688d2c
https://doi.org/10.1101/825315
https://doi.org/10.1101/825315