Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sylvia A. Wang"'
Autor:
Sunita Shankar, Jean Ching-Yi Tien, Ronald F. Siebenaler, Seema Chugh, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Xiao-Ming Wang, Ingrid J. Apel, Jessica Waninger, Sanjana Eyunni, Alice Xu, Malay Mody, Andrew Goodrum, Yuping Zhang, John J. Tesmer, Rahul Mannan, Xuhong Cao, Pankaj Vats, Sethuramasundaram Pitchiaya, Stephanie J. Ellison, Jiaqi Shi, Chandan Kumar-Sinha, Howard C. Crawford, Arul M. Chinnaiyan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Argonaute 2 (AGO2) binds RAS and is required for cellular transformation. Here, the authors establish a KRAS-driven mouse model of pancreatic cancer with conditional loss of AGO2 and show that the early phase of neoplastic lesion initiation is depend
Externí odkaz:
https://doaj.org/article/4879439f815846169a9d5e62cae6d7c2
Autor:
Yajing Liu, Sahezeel Awadia, Amy Delaney, Merna Sitto, Carl G. Engelke, Heli Patel, Andrew Calcaterra, Sylvia Zelenka-Wang, Hojin Lee, Joseph Contessa, Nouri Neamati, Mats Ljungman, Theodore S. Lawrence, Meredith A. Morgan, Alnawaz Rehemtulla
Publikováno v:
Translational Oncology, Vol 13, Iss 11, Pp 100834- (2020)
The Unfolded Protein Response (UPR) plays a key role in the adaptive response to loss of protein homeostasis within the endoplasmic reticulum (ER). The UPR has an adaptive function in protein homeostasis, however, sustained activation of the UPR due
Externí odkaz:
https://doaj.org/article/8565fd736ec64fb4919739945b14f89d
Autor:
Arul M. Chinnaiyan, Rohit Mehra, Sudhanshu Shukla, Fengyun Su, Kelly L. Harms, Douglas R. Fullen, Alison B. Durham, Sylvia Zelenka-Wang, Rajiv M. Patel, Javed Siddiqui, Xuhong Cao, Shannon Carskadon, Nallasivam Palanisamy, Paul W. Harms, Lisha Wang
Representative microphotographs of samples showing different MCPyV RNA in situ hybridization (RNA-ISH) intensity (400X magnification)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccb99898307e6d5b9fa984f43bb0637
https://doi.org/10.1158/1078-0432.22467446.v1
https://doi.org/10.1158/1078-0432.22467446.v1
Autor:
Arul M. Chinnaiyan, Rohit Mehra, Sudhanshu Shukla, Fengyun Su, Kelly L. Harms, Douglas R. Fullen, Alison B. Durham, Sylvia Zelenka-Wang, Rajiv M. Patel, Javed Siddiqui, Xuhong Cao, Shannon Carskadon, Nallasivam Palanisamy, Paul W. Harms, Lisha Wang
ISH product scores.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e73d02ff438e9d8868926ccddd7173
https://doi.org/10.1158/1078-0432.22467422
https://doi.org/10.1158/1078-0432.22467422
Autor:
Arul M. Chinnaiyan, Rohit Mehra, Sudhanshu Shukla, Fengyun Su, Kelly L. Harms, Douglas R. Fullen, Alison B. Durham, Sylvia Zelenka-Wang, Rajiv M. Patel, Javed Siddiqui, Xuhong Cao, Shannon Carskadon, Nallasivam Palanisamy, Paul W. Harms, Lisha Wang
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffc3c9c044a33818540dbc22e37b7de
https://doi.org/10.1158/1078-0432.22467428.v1
https://doi.org/10.1158/1078-0432.22467428.v1
Autor:
Arul M. Chinnaiyan, Rohit Mehra, Sudhanshu Shukla, Fengyun Su, Kelly L. Harms, Douglas R. Fullen, Alison B. Durham, Sylvia Zelenka-Wang, Rajiv M. Patel, Javed Siddiqui, Xuhong Cao, Shannon Carskadon, Nallasivam Palanisamy, Paul W. Harms, Lisha Wang
Read depth histograms across the Merkel cell polyomavirus (MCPyV) genome for two Merkel cell carcinoma (MCC) tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7384ea7f37bc1986497f025b2f68bb7f
https://doi.org/10.1158/1078-0432.22467434.v1
https://doi.org/10.1158/1078-0432.22467434.v1
Autor:
Arul M. Chinnaiyan, Rohit Mehra, Sudhanshu Shukla, Fengyun Su, Kelly L. Harms, Douglas R. Fullen, Alison B. Durham, Sylvia Zelenka-Wang, Rajiv M. Patel, Javed Siddiqui, Xuhong Cao, Shannon Carskadon, Nallasivam Palanisamy, Paul W. Harms, Lisha Wang
Purpose: Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine tumor of the skin. Merkel cell polyomavirus (MCPyV) plays an oncogenic role in the majority of MCCs. Detection of MCPyV in MCCs has diagnostic utility and prognostic potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8616a0b737faac061b31d2b01c56f9cc
https://doi.org/10.1158/1078-0432.c.6526637
https://doi.org/10.1158/1078-0432.c.6526637
Autor:
Lanbo Xiao, Abhijit Parolia, Yuanyuan Qiao, Pushpinder Bawa, Sanjana Eyunni, Rahul Mannan, Sandra E. Carson, Yu Chang, Xiaoju Wang, Yuping Zhang, Josh N. Vo, Steven Kregel, Stephanie A. Simko, Andrew D. Delekta, Mustapha Jaber, Heng Zheng, Ingrid J. Apel, Lisa McMurry, Fengyun Su, Rui Wang, Sylvia Zelenka-Wang, Sanjita Sasmal, Leena Khare, Subhendu Mukherjee, Chandrasekhar Abbineni, Kiran Aithal, Mital S. Bhakta, Jay Ghurye, Xuhong Cao, Nora M. Navone, Alexey I. Nesvizhskii, Rohit Mehra, Ulka Vaishampayan, Marco Blanchette, Yuzhuo Wang, Susanta Samajdar, Murali Ramachandra, Arul M. Chinnaiyan
Publikováno v:
Nature
The switch/sucrose non-fermentable (SWI/SNF) complex has a crucial role in chromatin remodelling1 and is altered in over 20% of cancers2,3. Here we developed a proteolysis-targeting chimera (PROTAC) degrader of the SWI/SNF ATPase subunits, SMARCA2 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6792ceed7ffa9433eeb3a2a771d4d4aa
http://europepmc.org/articles/PMC8770127
http://europepmc.org/articles/PMC8770127
Autor:
Erica Vormittag-Nocito, Rahul Mannan, Xiaoming Wang, Anya Chinnaiyan, Yuping Zhang, Sylvia Zelenka-Wang, Xuhong Cao, Todd M. Morgan, Khaled Hafez, Ulka Vaishampayan, Eman Abdulfatah, Arul M. Chinnaiyan, Saravana M. Dhanasekaran, Rohit Mehra
Publikováno v:
Human pathology. 130
Clear cell renal cell carcinoma (CCRCC) is a common renal malignancy known for its lethality and chromosome 3p aberrancies associated with loss of VHL. It has been shown that additional prognostic molecular markers exist in other transcriptional modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82dd6d6c65237d43708d86fe21608581
https://pubmed.ncbi.nlm.nih.gov/36511267
https://pubmed.ncbi.nlm.nih.gov/36511267
Autor:
Jeffrey L. Myers, Rahul Mannan, Rohit Mehra, Lanbo Xiao, Arul M. Chinnaiyan, Xiaoming Wang, Sylvia Zelenka-Wang, Allecia M. Wilson, Fengyun Su, Liron Pantanowitz, Rui Wang, Eman Abdulfatah, Xuhong Cao, Yuping Zhang, Lisa McMurry, Jeffrey M. Jentzen, Yuanyuan Qiao, Carol Farver
Publikováno v:
Communications medicine. 1
SARS-CoV-2 is a highly contagious virus that causes the disease COVID-19. We have recently reported that androgens regulate the expression of SARS-CoV-2 host entry factors ACE2 and TMPRSS2, and androgen receptor (AR) in lung epithelial cells. We also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f119464f3408302c7ee46aea09566a9d
https://pubmed.ncbi.nlm.nih.gov/35602214
https://pubmed.ncbi.nlm.nih.gov/35602214