Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sylvette Ayala-Torres"'
Autor:
Jamila R. Momand, Marissa Perez, Sylvette Ayala-Torres, Christi A. Walter, Thomas J. Prihoda, Kristine S. Vogel, C. Alex McMahan, Rebecca A. Garcia, Carlos A. Torres-Ramos, Karina Acevedo-Torres, Kim Hildreth
Publikováno v:
Molecular Reproduction and Development. 78:906-919
The prevalence of spontaneous mutations increases with age in the male germline; consequently, older men have an increased risk of siring children with genetic disease due to de novo mutations. The lacI transgenic mouse can be used to study paternal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca4d85de2deab32c531eeb43c1cb5734
https://doi.org/10.1002/mrd.21374
https://doi.org/10.1002/mrd.21374
Autor:
Karina Acevedo-Torres, Sylvette Ayala-Torres, Carlos A. Torres-Ramos, Sharon Fonseca-Williams
Publikováno v:
Environmental and Molecular Mutagenesis. 50:317-327
The Saccharomyces cerevisiae APN1 gene that participates in base excision repair has been localized both in the nucleus and the mitochondria. APN1 deficient cells (apn1 Delta) show increased mutation frequencies in mitochondrial DNA (mtDNA) suggestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f49d0c90d5ffb96f77a8037458c772
https://doi.org/10.1002/em.20462
https://doi.org/10.1002/em.20462
Publikováno v:
Methods. 22:135-147
Soon after discovery of the polymerase chain reaction (PCR), various laboratories have attempted to use quantitative PCR (QPCR) to detect DNA damage in specific gene segments. The development of techniques that facilitate long PCR increased the sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa3f7420d0a438c1c0b6a5e3236fd6c
https://doi.org/10.1006/meth.2000.1054
https://doi.org/10.1006/meth.2000.1054
Autor:
Rheem D. Medh, Betty H. Johnson, E. Brad Thompson, Naseem H. Ansari, Feng Zhou, Weiping Zhang, Sylvette Ayala-Torres
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 69:453-461
In clones of the CEM human acute lyumphoblastic leukemic cell line, glucocorticoids, oxysterols and activators of the cAMP pathway acting synergistically with glucocorticoids, each can cause apoptotic cell death. Morphologically and kinetically, thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1949457a4196172e13d85cd7db9bd21
https://doi.org/10.1016/s0960-0760(99)00063-1
https://doi.org/10.1016/s0960-0760(99)00063-1
Publikováno v:
Experimental Cell Research. 246:193-202
Previously we have demonstrated that treatment of the human lymphoblastic leukemic CEM cells with 25-hydroxycholesterol (25OHC) induces apoptosis. In the present study, we show that both c-myc mRNA and c-Myc protein levels are reduced only in oxyster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7843ab2641d8c20f83a8d1e90e22d2
https://doi.org/10.1006/excr.1998.4308
https://doi.org/10.1006/excr.1998.4308
Autor:
Almas Siddiqui, Carlos A. Torres-Ramos, Sulay Rivera-Sánchez, David G. Nicholls, Julie K. Andersen, Karina Acevedo-Torres, María del R. Castro, Sylvette Ayala-Torres, Anand Rane
Oxidative stress and mitochondrial dysfunction have been implicated in the pathology of HD; however, the precise mechanisms by which mutant huntingtin modulates levels of oxidative damage in turn resulting in mitochondrial dysfunction are not known.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a72034711247e97ac81297e0b02fbef
https://europepmc.org/articles/PMC3846402/
https://europepmc.org/articles/PMC3846402/
Autor:
Angel A. Isidro, José Paz, Edu Suarez, Edmundo Kraiselburd, María del R. Castro, León Ferder, Sylvette Ayala-Torres
While the mechanisms of cellular aging remain controversial, a leading hypothesis is that mitochondrial oxidative stress and mitochondrial dysfunction play a critical role in this process. Here, we provide data in aging rhesus macaques supporting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7f096cb4699d5fd54ea2f6a9ab8c95
https://europepmc.org/articles/PMC3770191/
https://europepmc.org/articles/PMC3770191/
Autor:
Kristine S, Vogel, Marissa, Perez, Jamila R, Momand, Karina, Acevedo-Torres, Kim, Hildreth, Rebecca A, Garcia, Carlos A, Torres-Ramos, Sylvette, Ayala-Torres, Thomas J, Prihoda, C Alex, McMahan, Christi A, Walter
Publikováno v:
Molecular reproduction and development. 78(12)
The prevalence of spontaneous mutations increases with age in the male germline; consequently, older men have an increased risk of siring children with genetic disease due to de novo mutations. The lacI transgenic mouse can be used to study paternal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcfa2e97433baceab02ab514b40647e1
https://pubmed.ncbi.nlm.nih.gov/21919107
https://pubmed.ncbi.nlm.nih.gov/21919107
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5d5b0be121385e8a4723796bd3f66b7
https://doi.org/10.1096/fasebj.24.1_supplement.878.7
https://doi.org/10.1096/fasebj.24.1_supplement.878.7