Characterisation of zinc delivery from a nipple shield delivery system using a breastfeeding simulation apparatus.

Autor: Rebekah L Scheuerle, Sylvaine F A Bruggraber, Stephen E Gerrard, Richard A Kendall, Catherine Tuleu, Nigel K H Slater

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0171624 (2017)

Zinc delivery from a nipple shield delivery system (NSDS), a novel platform for administering medicines to infants during breastfeeding, was characterised using a breastfeeding simulation apparatus. In this study, human milk at flow rates and pressur

Externí odkaz: https://doaj.org/article/52e1f424f69342e98e90d30edc9572d0

Zinc delivery from non-woven fibres within a therapeutic nipple shield

Autor: Daniel Markl, Sylvaine F. A. Bruggraber, Axel Zeitler, Ljiljana Fruk, Theresa Maier, Rebekah L. Scheuerle, Nigel K.H. Slater

A Therapeutic Nipple Shield (TNS) was previously developed to respond to the global need for new infant therapeutic delivery technologies. However, the release efficiency for the same Active Pharmaceutical Ingredient (API) from different therapeutic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069fb22ad34f3294bab136dde76e55b1
https://strathprints.strath.ac.uk/64137/1/Maier_etal_IJP_2018_Zinc_delivery_from_non_woven_fibres_within_a_therapeutic.pdf

A 1-h time interval between a meal containing iron and consumption of tea attenuates the inhibitory effects on iron absorption: a controlled trial in a cohort of healthy UK women using a stable iron isotope

Autor: Dagmar Koller, Sylvaine F. A. Bruggraber, Jack R. Dainty, Salma F Ahmad Fuzi, Dora Ia Pereira, Sohail Mushtaq

Publikováno v: The American journal of clinical nutrition. 106(6)

Background: Tea has been shown to be a potent inhibitor of nonheme iron absorption, but it remains unclear whether the timing of tea consumption relative to a meal influences iron bioavailability. Objective: The aim of the study was to investigate th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b2550676521f4adf6836ee08303fa5
https://pubmed.ncbi.nlm.nih.gov/29046302

A nano-disperse ferritin-core mimetic that efficiently corrects anemia without luminal iron redox activity

Autor: Sylvaine F. A. Bruggraber, Jonathan J. Powell, Nicole Hondow, Timothy J. Pennycook, Dora I. A. Pereira, Andy Brown, Gladys O. Latunde-Dada, Lynsey K. Poots, Nuno Jorge Rodrigues Faria, Robert J. Simpson

Publikováno v: Nanomedicine
Nanomedicine: nanotechnology, biology and medicine
Powell, J, Bruggraber, S, Faria, N, Poots, L K, Hondow, N, Pennycook, T J, Latunde-Dada, G, Simpson, R, Brown, A P & Pereira, D I A 2014, ' A nano-disperse ferritin-core mimetic that efficiently corrects anemia without luminal iron redox activity ', Nanomedicine : nanotechnology, biology, and medicine, vol. 10, no. 7, pp. 1529-1538 . https://doi.org/10.1016/j.nano.2013.12.011

The 2-5 nm Fe(III) oxo-hydroxide core of ferritin is less ordered and readily bioavailable compared to its pure synthetic analogue, ferrihydrite. We report the facile synthesis of tartrate-modified, nano-disperse ferrihydrite of small primary particl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b8116270f920f54d1ea1ca159ba882

Nanoparticulate iron(III) oxo-hydroxide delivers safe iron that is well absorbed and utilised in humans

Autor: Sylvaine F. A. Bruggraber, Nuno Jorge Rodrigues Faria, Chris D. Vulpe, Gregory J. Anderson, Mani Tagmount, Lynsey K. Poots, Mohamad F. Aslam, Jonathan J. Powell, David M. Frazer, Dora I. A. Pereira

Publikováno v: Nanomedicine

Iron deficiency is the most common nutritional disorder worldwide with substantial impact on health and economy. Current treatments predominantly rely on soluble iron which adversely affects the gastrointestinal tract. We have developed organic acid-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53eef3d0ce156a274e2b2be95f05ee3
http://europepmc.org/articles/PMC4228177