Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sylvaine Cren"'
Autor:
Carina Lotz-Jenne, Roland Lange, Sylvaine Cren, Geoffroy Bourquin, Laksmei Goglia, Thierry Kimmerlin, Micha Wicki, Manon Müller, Nadia Artico, Sabine Ackerknecht, Philippe Pfaff, Christoph Joesch, Aengus Mac Sweeney
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Tryptophan-2,3-dioxygenase (TDO2) and indoleamine-2,3-dioxygenase (IDO1) are structurally distinct heme enzymes that catalyze the conversion of L-tryptophan to N-formyl-kynurenine, and play important roles in metabolism, inflammation, and tu
Externí odkaz:
https://doaj.org/article/3e1980a3ec7c40e68c87ab5aff77895f
Publikováno v:
CHIMIA, Vol 60, Iss 3 (2006)
Cylindricines, lepadiformine, and fasicularin are marine alkaloids with a common novel pyrrolo- and pyrido[1,2-j]quinoline skeleton. They have recently been isolated from various tunicates and have shown interesting cytotoxic effects which could be a
Externí odkaz:
https://doaj.org/article/38c2fca6e179473f9be490bf82f8056d
Publikováno v:
Encyclopedia of Reagents for Organic Synthesis. :1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75cbf9fd433086653df38a53e2c670fa
https://doi.org/10.1002/047084289x.rd062.pub3
https://doi.org/10.1002/047084289x.rd062.pub3
Autor:
Carina Lotz-Jenne, Sylvaine Cren, Christoph Joesch, Sabine Ackerknecht, Jennifer Brandes, Claire Moebs, Dominik Hartl, Felix Hartrampf, Philippe Guerry, Julien Pothier, Alexia Chavanton-Arpel
Publikováno v:
Cancer Immunology Research. 10:B66-B66
Indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO2) catalyze the oxidation of L-Tryptophan (TRP) leading to the formation of immunosuppressive kynurenine (KYN) pathway metabolites. According to TCGA, a substantial fraction of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f95478d5084597691f29d814a08334d4
https://doi.org/10.1158/2326-6074.tumimm22-b66
https://doi.org/10.1158/2326-6074.tumimm22-b66
Autor:
Simon Woodward, Sylvaine Cren, Ali Sadeghi-Khomami, Neil R. Thomas, Richard I. Robinson, Sarathy Karunan Partha, Blake Zheng, Kate Slowski, David A. R. Sanders, Lindsey Berast
Publikováno v:
Molecular Informatics. 30:873-883
UDP-galactopyranose mutase (UGM) is a flavo-enzyme involved in the bacterial cell wall biosynthesis. UGM catalyzes the reversible isomerization of UDP-galactopyranose (UDP-Galp) to UDP-galactofuranose (UDP-Galf). UDP-Galf is the activated precursor o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d97e11e6969ec33bd33d6301463ff6
https://doi.org/10.1002/minf.201100085
https://doi.org/10.1002/minf.201100085
Publikováno v:
Org. Biomol. Chem.. 2:2418-2420
Two iminosugars have been designed and synthesized as potential inhibitors of UDP-Galf transferase, an enzyme involved in Mycobacterium tuberculosis cell wall biosynthesis. The design is based on a proposed model of the transition state for the trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7618d8f2942ee4b517b65ada533792
https://doi.org/10.1039/b411554f
https://doi.org/10.1039/b411554f
Publikováno v:
Tetrahedron Letters. 43:2749-2751
The sulfoximination of a range of sulfoxides possessing functionalised side-chains using mesitylene sulfonyl hydroxylamine or iminoiodane reagents is discussed. The use of iminoiodane reagents possessing removable protecting groups (p-nosyl and Ses)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e377121dd9f8219ef4d5a534a548c71
https://doi.org/10.1016/s0040-4039(02)00378-7
https://doi.org/10.1016/s0040-4039(02)00378-7
Publikováno v:
ChemInform. 33
The sulfoximination of a range of sulfoxides possessing functionalised side-chains using mesitylene sulfonyl hydroxylamine or iminoiodane reagents is discussed. The use of iminoiodane reagents possessing removable protecting groups (p-nosyl and Ses)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83aa99388429eb5b63fe74dc3cd4e94
https://doi.org/10.1002/chin.200229125
https://doi.org/10.1002/chin.200229125
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
[14976-54-6] C8H18N2O2 (MW 174.24) InChI = 1S/C8H18N2O2/c1-7(2,3)11-9-10-12-8(4,5)6/h1-6H3 InChIKey = OAPFBXRHYINFDV-UHFFFAOYSA-N (E) [82554-97-0] InChI = 1S/C8H18N2O2/c1-7(2,3)11-9-10-12-8(4,5)6/h1-6H3/b10-9+ InChIKey = OAPFBXRHYINFDV-MDZDMXLPSA-N (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::016ffa6c46af63ad00be8c1fe57bc34e
https://doi.org/10.1002/047084289x.rd062.pub2
https://doi.org/10.1002/047084289x.rd062.pub2
Publikováno v:
ChemInform. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de2cfd43f4e09746d8a20611addcca50
https://doi.org/10.1002/chin.200549172
https://doi.org/10.1002/chin.200549172