Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sylvain Perriot"'
Autor:
Stéphanie Bibert, Mathieu Quinodoz, Sylvain Perriot, Fanny S. Krebs, Maxime Jan, Rita C. Malta, Emilie Collinet, Mathieu Canales, Amandine Mathias, Nicole Faignart, Eliane Roulet-Perez, Pascal Meylan, René Brouillet, Onya Opota, Leyder Lozano-Calderon, Florence Fellmann, Nicolas Guex, Vincent Zoete, Sandra Asner, Carlo Rivolta, Renaud Du Pasquier, Pierre-Yves Bochud
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Encephalitis is a rare and potentially fatal manifestation of herpes simplex type 1 infection. Following genome-wide genetic analyses, we identified a previously uncharacterized and very rare heterozygous variant in the E3 ubiquitin ligase W
Externí odkaz:
https://doaj.org/article/d87fb10f72004b578992242a02fb6927
Autor:
Amandine Mathias, Sylvain Perriot, Samuel Jones, Mathieu Canales, Raphaël Bernard-Valnet, Marie Gimenez, Nathan Torcida, Larise Oberholster, Andreas F. Hottinger, Anastasia Zekeridou, Marie Theaudin, Caroline Pot, Renaud Du Pasquier
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Background and objectivesUp to 46% of patients with presumed autoimmune limbic encephalitis are seronegative for all currently known central nervous system (CNS) antigens. We developed a cell-based assay (CBA) to screen for novel neural antibodies in
Externí odkaz:
https://doaj.org/article/1f008ff52d0846918137fd78bd9676ce
Autor:
Chiara Stüdle, Hideaki Nishihara, Sven Wischnewski, Laila Kulsvehagen, Sylvain Perriot, Hiroshi Ishikawa, Horst Schroten, Stephan Frank, Nikolaus Deigendesch, Renaud Du Pasquier, Lucas Schirmer, Anne-Katrin Pröbstel, Britta Engelhardt
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background As a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several months post infection. However, cell type-specific routes of brain infection and underlying me
Externí odkaz:
https://doaj.org/article/d9433b49b0e545ddb46501b777be8935
Autor:
Larise Oberholster, Amandine Mathias, Sylvain Perriot, Emma Blaser, Mathieu Canales, Samuel Jones, Lucas Culebras, Marie Gimenez, G. Campbell Kaynor, Alexey Sapozhnik, Kevin Richetin, Susan Goelz, Renaud Du Pasquier
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT JC polyomavirus (JCPyV) is an opportunistic virus that remains in a latent state in the kidneys and lymphoid organs of more than half of the human adult population. In rare cases of severe immune suppression, the virus is able to establish a
Externí odkaz:
https://doaj.org/article/4fd2d2222ca44d3287e71a4122e664db
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101620- (2022)
Summary: This protocol describes the generation and characterization of human induced pluripotent stem cells (hiPSCs) from erythroblasts. A key difference with classical protocols is the reprogramming of erythroblasts from a simple blood draw as oppo
Externí odkaz:
https://doaj.org/article/c8005267449147b0a44ed78683ca1ef8
Autor:
Romain Perbet, Valentin Zufferey, Elodie Leroux, Enea Parietti, Jeanne Espourteille, Lucas Culebras, Sylvain Perriot, Renaud Du Pasquier, Séverine Bégard, Vincent Deramecourt, Nicole Déglon, Nicolas Toni, Luc Buée, Morvane Colin, Kevin Richetin
Publikováno v:
Cells, Vol 12, Iss 7, p 985 (2023)
Tauopathies are neurodegenerative disorders involving the accumulation of tau isoforms in cell subpopulations such as astrocytes. The origins of the 3R and 4R isoforms of tau that accumulate in astrocytes remain unclear. Extracellular vesicles (EVs)
Externí odkaz:
https://doaj.org/article/966d652067e24b4c873c33fe5f4dc2c7
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100902- (2021)
Summary: This protocol describes how to obtain human astrocytes from human-induced pluripotent stem cells (hiPSCs) in chemically defined media, without the use of fetal bovine serum (FBS). FBS eases the differentiation of astrocytes but also deeply a
Externí odkaz:
https://doaj.org/article/306f5e2d551643b8aa0d371b2a23ea6c
Autor:
Sylvain Perriot, Amandine Mathias, Guillaume Perriard, Mathieu Canales, Nils Jonkmans, Nicolas Merienne, Cécile Meunier, Lina El Kassar, Anselme L. Perrier, David-Axel Laplaud, Myriam Schluep, Nicole Déglon, Renaud Du Pasquier
Publikováno v:
Stem Cell Reports, Vol 11, Iss 5, Pp 1199-1210 (2018)
Summary: Recent studies highlighted the importance of astrocytes in neuroinflammatory diseases, interacting closely with other CNS cells but also with the immune system. However, due to the difficulty in obtaining human astrocytes, their role in thes
Externí odkaz:
https://doaj.org/article/4835770e4d1c4fb88ad494f4e27a421a
Autor:
Romain Perbet, Valentin Zufferey, Elodie Leroux, Enea Parietti, Jeanne Espourteille, Lucas Culebras, Sylvain Perriot, Renaud Du Pasquier, Séverine Bégard, Vincent Deramecourt, Nicole Déglon, Nicolas Toni, Luc Buée, Morvane Colin, Kevin Richetin
Tauopathies are neurodegenerative disorders involving the accumulation of tau isoforms in cell subpopulations such as astrocytes. The origins of the 3R and 4R isoforms of tau that accumulate in astrocytes remain unclear.Extracellular vesicles (EVs) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8dea16b88d68aba104be10be037d6cf
https://doi.org/10.1101/2023.02.15.527595
https://doi.org/10.1101/2023.02.15.527595
Autor:
Amandine Mathias, Vasiliki Pantazou, Sylvain Perriot, Mathieu Canales, Samuel Jones, Larise Oberholster, Michaël Moulin, Craig Fenwick, Raphaël Bernard-Valnet, Marie Théaudin, Caroline Pot, Renaud A. Du Pasquier
Publikováno v:
Neurology - Neuroimmunology Neuroinflammation. 10:e200084
Background and ObjectiveDepleting CD20+B cells is the primary mechanism by which ocrelizumab (OCRE) is efficient in persons with multiple sclerosis (pwMS). However, the exact role of OCRE on other immune cell subsets directly or indirectly remains el