LFA-1 and kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motors.

Autor: Eidell KP; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Lovy A; Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA., Sylvain NR; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Scangarello FA; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Muendlein HI; Graduate Program in Genetics, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Ophir MJ; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Nguyen K; Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111, USA., Seminario MC; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA., Bunnell SC; Department of Immunology, Tufts University School of Medicine, Boston, MA 02111, USA.

Publikováno v: Journal of cell science [J Cell Sci] 2021 Aug 15; Vol. 134 (16). Date of Electronic Publication: 2021 Aug 27.

Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses.

Autor: Sylvain NR; Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA., Nguyen K, Bunnell SC

Publikováno v: Science signaling [Sci Signal] 2011 Mar 08; Vol. 4 (163), pp. ra14. Date of Electronic Publication: 2011 Mar 08.