Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sylvain Molon-Noblot"'
Publikováno v:
Toxicologic Pathology. 31:310-320
This study compared the effects of ad libitum (AL) overfeeding and moderate or marked dietary restriction (DR) on the pathogenesis of aged-related pituitary gland changes in Sprague—Dawley (SD) rats. SD rats were fed Purina Certified Rodent Diet AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415cd0df279ddc782a23ad6c187483c7
https://doi.org/10.1080/01926230390204351
https://doi.org/10.1080/01926230390204351
Morphological Changes in the Pituitary Gland of Dogs Chronically Exposed to Exogenous Growth Hormone
Autor:
Lea G. Stabinski, Matthew J. van Zwieten, Sylvain Molon-Noblot, Chennekatu P. Peter, Pierre Duprat, Srinivasa Prahalada, Philippe Laroque, Chao-Min Hoe
Publikováno v:
Toxicologic Pathology. 26:201-206
Growth hormone (GH) synthesis and release from the pituitary is regulated by hypothalamic releasing hormone, insulin-like growth factor-1 (IGF-1). and somatostatin. However, the potential effects of pharmacological doses of exogenous GH on the pituit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c33989fb20d4b23339a7ee07853d0b0b
https://doi.org/10.1177/019262339802600202
https://doi.org/10.1177/019262339802600202
Autor:
Lea G. Stabinski, Philippe Laroque, Sylvain Molon-Noblot, Pierre Duprat, Srinivasa Prahalada, Matthew J. van Zwieten, Chennekatu P. Peter, Chao-Min Hoe
Publikováno v:
Toxicologic Pathology. 26:207-212
Administration of growth hormone (GH) results in increased body weight gain in dogs. Increased body weight gain is believed to be a result of the trophic effect of GH on the musculoskeletal system. However, edema is one of the side effects described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d27d37f645c6356c17dbbb7bf7fbe19
https://doi.org/10.1177/019262339802600203
https://doi.org/10.1177/019262339802600203
Publikováno v:
Toxicologic Pathology. 23:606-619
L-694,492 (DUP 532), an angiotensin II (AII) receptor antagonist, was given orally at 125 mg/kh/day to rats and monkeys for up to 6 mo to assess the effects of the compound on juxtaglomerular (JG) cells. In rats, mild JG cell hypertrophy/hyperplasia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7198d0c2e10bc6af48cbd3b53992d3a
https://doi.org/10.1177/019262339502300319
https://doi.org/10.1177/019262339502300319
Autor:
Peter H. Berry, Lea R. Gordon, Chennekatu P. Peter, Christine Boussiquet-Leroux, Nicholas Tonkonoh, G. Durand-Cavagna, Roger A. Owen, Sylvain Molon-Noblot
Publikováno v:
Toxicologic Pathology. 21:449-455
Renal papillary cytoplasmic granularity (RPCG) induced by carbonic anhydrase inhibitors (CAIs) in rats is characterized by the accumulation of dense secondary lysosomes in epithelial, endothelial, and interstitial cells and may be related to drug-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd3e694a4d4d7473356031ea6a882e5
https://doi.org/10.1177/019262339302100504
https://doi.org/10.1177/019262339302100504
Autor:
Glen K. Miller, Gordon K. Wollenberg, Sylvain Molon-Noblot, Christine P. Chan, Srinivasa Prahalada, Georgia Farris
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 97(2)
Recombinant rat growth hormone (rrGH) and recombinant mouse growth hormone (rmGH) were developed to evaluate the potential carcinogenicity of each biologically active growth hormone (GH) as assessed in the respective species. Biological activities of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff833ddb14c7f85d8e54fec3e427b2fa
https://pubmed.ncbi.nlm.nih.gov/17372281
https://pubmed.ncbi.nlm.nih.gov/17372281
Publikováno v:
Toxicologic pathology. 33(5)
The effects of ad libitum (AL) feeding and marked dietary restriction (DR) on spontaneous age-related skeletal muscle changes in male Sprague–Dawley (SD) rats were evaluated at 1 and 2 years. SD rats were fed Certified UAR A04C Rodent Chow ad libit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78ea25ab0277ccd132416e6a807d81f
https://pubmed.ncbi.nlm.nih.gov/16178124
https://pubmed.ncbi.nlm.nih.gov/16178124
Autor:
Smith David W, Sylvain Molon-Noblot, Carmen De Felipe, George McAllister, M.R. Knowles, Fraser Murray, Philippe A. Laroque, Nadia M.J. Rupniak, Paul C. Guest, Kamran Salim, Stephen P. Hunt
Antidepressants are widely prescribed in the treatment of depression, although the mechanism of how they exert their therapeutic effects is poorly understood. To shed further light on their mode of action, we have attempted to identify a common prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1294cf497275d2dd91769a338214b320
http://hdl.handle.net/10261/309118
http://hdl.handle.net/10261/309118
Publikováno v:
Neuroscience letters. 371(1)
Glutamate together with its N-methyl-d-aspartate (NMDA) receptors has an important role in the transmission of stimuli in the spinal cord. Whilst the expression of the various NMDA receptor subunits within the spinal cord has been investigated the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1537ef8d5091fba402bf48fc959bc8e1
https://pubmed.ncbi.nlm.nih.gov/15500960
https://pubmed.ncbi.nlm.nih.gov/15500960
Publikováno v:
Toxicologic pathology. 29(3)
This study compared the effects of ad libitum (AL) overfeeding and moderate or marked dietary restriction (DR) on aged-related degenerative and proliferative changes of the endocrine pancreas in Sprague—Dawley (SD) rats. SD rats were fed Purina Cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9251ac6b16de7c82db22910b508a909f
https://pubmed.ncbi.nlm.nih.gov/11442021
https://pubmed.ncbi.nlm.nih.gov/11442021