Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Sylvain L, Guérin"'
Publikováno v:
Cells, Vol 13, Iss 12, p 1023 (2024)
Uveal melanoma (UM), a distinct subtype of melanoma, presents unique challenges in its clinical management due to its complex molecular landscape and tendency for liver metastasis. This review highlights recent advancements in understanding the molec
Externí odkaz:
https://doaj.org/article/8bad78abdc8c4dc8ab3bfa9cd669f5a5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13182 (2023)
Clusterin (CLU) is a glycoprotein originally discovered in 1983 in ram testis fluid. Rapidly observed in other tissues, it was initially given various names based on its function in different tissues. In 1992, it was finally named CLU by consensus. N
Externí odkaz:
https://doaj.org/article/31753b5dac4144e4880bd77aae43b0b6
Autor:
Sergio Cortez Ghio, Martin A. Barbier, Emilie J. Doucet, Imad Debbah, Meryem Safoine, Gaëtan Le-Bel, Andréanne Cartier, Emilie Jolibois, Amélie Morissette, Danielle Larouche, Julie Fradette, Sylvain L. Guérin, Alain Garnier, Lucie Germain
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 1821 (2023)
In our experience, keratinocytes cultured in feeder-free conditions and in commercially available defined and serum-free media cannot be as efficiently massively expanded as their counterparts grown in conventional bovine serum-containing medium, nor
Externí odkaz:
https://doaj.org/article/550f8baa706841279122d3aeb51a417a
Autor:
Pascale Desjardins, Rébecca Berthiaume, Camille Couture, Gaëtan Le-Bel, Vincent Roy, François Gros-Louis, Véronique J. Moulin, Stéphanie Proulx, Sylvain Chemtob, Lucie Germain, Sylvain L. Guérin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12201 (2022)
Corneal wound healing involves communication between the different cell types that constitute the three cellular layers of the cornea (epithelium, stroma and endothelium), a process ensured in part by a category of extracellular vesicles called exoso
Externí odkaz:
https://doaj.org/article/99dbce568d9043bb818f8fb96b3711eb
Autor:
Geneviève Rioux, Florence Turgeon, Gaëtan Le-Bel, Camille Grenier, Sylvain L. Guérin, Roxane Pouliot
Publikováno v:
Cells, Vol 11, Iss 18, p 2904 (2022)
Psoriasis is a complex, immune-mediated skin disease involving a wide range of epithelial and immune cells. The underlying mechanisms that govern the epidermal defects and immunological dysfunction observed in this condition remain largely unknown. I
Externí odkaz:
https://doaj.org/article/b1d455438a1743178122b37f5128bea4
Autor:
Gaëtan Le-Bel, Pascale Desjardins, Christelle Gross, Sergio Cortez Ghio, Camille Couture, Lucie Germain, Sylvain L. Guérin
Publikováno v:
Cells, Vol 11, Iss 17, p 2716 (2022)
Besides being a powerful model to study the mechanisms of corneal wound healing, tissue-engineered human corneas (hTECs) are sparking interest as suitable substitutes for grafting purposes. To ensure the histological and physiological integrity of hT
Externí odkaz:
https://doaj.org/article/fe534afe37e34589b40216d38db97f69
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1564 (2022)
Uveal melanoma (UM) remains the most common intraocular malignancy among diseases affecting the adult eye. The primary tumor disseminates to the liver in half of patients and leads to a 6 to 12-month survival rate, making UM a particularly aggressive
Externí odkaz:
https://doaj.org/article/3ef2a5c4ba114ca583406d0e286d393c
Autor:
Christelle Gross, Gaëtan Le-Bel, Pascale Desjardins, Manel Benhassine, Lucie Germain, Sylvain L. Guérin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12426 (2021)
In order to reduce the need for donor corneas, understanding of corneal wound healing and development of an entirely tissue-engineered human cornea (hTECs) is of prime importance. In this study, we exploited the hTEC to determine how deep wound heali
Externí odkaz:
https://doaj.org/article/0dc8252090374a42bb40e44f4ce68fb9
Autor:
Gaëtan Le-Bel, Louis-Philippe Guérin, Patrick Carrier, Frédéric Mouriaux, Lucie Germain, Sylvain L. Guérin, Richard Bazin
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 15, Iss , Pp - (2019)
Purpose: In this study, we evaluated the feasibility of recovering the corneal surface integrity in a patient suffering from unilateral LSCD through the transplantation of cultured autologous corneal epithelial cells. Methods: Human corneal epithelia
Externí odkaz:
https://doaj.org/article/6f6378c19f084cfd835c15a328a6ef52
Autor:
Louis-Philippe Guérin, Gaëtan Le-Bel, Pascale Desjardins, Camille Couture, Elodie Gillard, Élodie Boisselier, Richard Bazin, Lucie Germain, Sylvain L. Guérin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1291 (2021)
Each day, about 2000 U.S. workers have a job-related eye injury requiring medical treatment. Corneal diseases are the fifth cause of blindness worldwide. Most of these diseases can be cured using one form or another of corneal transplantation, which
Externí odkaz:
https://doaj.org/article/14f9b98a34464972a02d70767587aca4