Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sylvain J. Le Marchand"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100916- (2021)
Western blotting (WB), enzyme-linked immunosorbent assay (ELISA) and flow cytometry (FC) have long been used to assess and quantitate relative protein expression in cultured cells and tissue samples. However, WB and ELISA have limited ability to mean
Externí odkaz:
https://doaj.org/article/f7cd18ae19d14d628255d3cf4b843cad
Autor:
Nathan T Henderson, Sylvain J Le Marchand, Martin Hruska, Simon Hippenmeyer, Liqun Luo, Matthew B Dalva
Publikováno v:
eLife, Vol 8 (2019)
Cortical networks are characterized by sparse connectivity, with synapses found at only a subset of axo-dendritic contacts. Yet within these networks, neurons can exhibit high connection probabilities, suggesting that cell-intrinsic factors, not prox
Externí odkaz:
https://doaj.org/article/942c71b1ac154bfcbdb7b7535b836ec0
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss, Pp 100916-(2021)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Western blotting (WB), enzyme-linked immunosorbent assay (ELISA) and flow cytometry (FC) have long been used to assess and quantitate relative protein expression in cultured cells and tissue samples. However, WB and ELISA have limited ability to mean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f396db8167c0c5a42387cb6e94f5af1
http://www.sciencedirect.com/science/article/pii/S2405580821000108
http://www.sciencedirect.com/science/article/pii/S2405580821000108
Autor:
Sylvain J Le Marchand, David W Piston
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47084 (2012)
The mechanisms of glucagon secretion and its suppression by glucose are presently unknown. This study investigates the relationship between intracellular calcium levels ([Ca(2+)](i)) and hormone secretion under low and high glucose conditions. We exa
Externí odkaz:
https://doaj.org/article/07c87648720242b9a6f3b3125b0b67ba
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 14:571-584
In vitro transporter kinetics are typically analyzed by steady-state Michaelis-Menten approximations. However, no clear evidence exists that these approximations, applied to multiple transporters in biological membranes, yield system-independent mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a52139554d5afc71ed10e4808b64e7e
https://doi.org/10.1080/17425255.2018.1480720
https://doi.org/10.1080/17425255.2018.1480720
Publikováno v:
Nature neuroscience
Experience results in long-lasting changes in dendritic spine size, yet how the molecular architecture of the synapse responds to plasticity remains poorly understood. Here, a combined approach of multi-color stimulated emission depletion microscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205125789c7a25d63f064fa02458e94b
http://europepmc.org/articles/PMC5920789
http://europepmc.org/articles/PMC5920789
Autor:
Sylvain J. Le Marchand, Matthew B. Dalva, Liqun Luo, Simon Hippenmeyer, Martin Hruska, Nathan T Henderson
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Cortical networks are characterized by sparse connectivity, with synapses found at only a subset of axo-dendritic contacts. Yet within these networks, neurons can exhibit high connection probabilities, suggesting that cell-intrinsic factors, not prox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636a54e0d30553fb193887bc39fe1a95
https://elifesciences.org/articles/41563
https://elifesciences.org/articles/41563
Publikováno v:
Drug Metabolism and Disposition. 45:145-151
From fits of drug transport kinetics across confluent MDCKII-hMDR1-NKI and Caco-2 cell monolayers we estimated the levels of efflux active P-glycoprotein (P-gp) in these two cell lines (companion paper). In the present work, we compared the efflux ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602c64bcc0d298d99a812ee9ef9a32ed
https://doi.org/10.1124/dmd.116.072157
https://doi.org/10.1124/dmd.116.072157
Publikováno v:
Nature neuroscience
Organization of signaling complexes at excitatory synapses by membrane-associated guanylate kinase (MAGUK) proteins regulates synapse development, plasticity, senescence and disease. Post-translational modification of MAGUK family proteins can drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e1423cb1058e33291f2151b201be86
https://doi.org/10.1038/nn.4140
https://doi.org/10.1038/nn.4140