Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Sylvain Goutelle"'
Autor:
Paul Chabert, Judith Provoost, Sabine Cohen, Céline Dupieux-Chabert, Laurent Bitker, Tristan Ferry, Sylvain Goutelle, Jean-Christophe Richard
Publikováno v:
Annals of Intensive Care, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Background Cefoxitin is active against some extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE), but has not been evaluated so far in the intensive care unit (ICU) settings. Data upon its pharmacokinetics (PK), tolerance an
Externí odkaz:
https://doaj.org/article/7ba14b2686d2460aba013f46de1c987c
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1081 (2023)
Imatinib is a targeted cancer therapy that has significantly improved the care of patients with chronic myeloid leukemia (CML) and gastrointestinal stromal tumor (GIST). However, it has been shown that the recommended dosages of imatinib are associat
Externí odkaz:
https://doaj.org/article/c16005e152ce45049eef7c6700f01b38
Autor:
Sylvain Goutelle, Yann Thoma, Roxane Buffet, Michael Philippe, Thierry Buclin, Monia Guidi, Chantal Csajka
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2107 (2022)
Busulfan, a drug used in conditioning prior to hematopoietic stem cell transplantation (HSCT) in children, has a narrow therapeutic margin. The model-informed precision dosing (MIPD) of busulfan is desirable, but there is a lack of validated tools. T
Externí odkaz:
https://doaj.org/article/0a811a747d7a44b69b3791c248263d27
Autor:
Blandine De La Gastine, Soizic Percevault, Laurent Varin, Nicolas Richard, Fabienne Fobe, Benoît Plaud, Georges Daccache, Vincent Compere, Jean-Jacques Parienti, Antoine Coquerel, Magalie Loilier, Nathalie Bleyzac, Laurent Bourguignon, Sylvain Goutelle, Véronique Lelong-Boulouard
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2177 (2022)
Cytochrome P450 2D6 (CYP2D6) gene polymorphisms influence the exposure to tramadol (T) and its pharmacologically active metabolite, O-demethyl tramadol (O-dT). Tramadol has been considered as a candidate probe drug for CYP2D6 phenotyping. The objecti
Externí odkaz:
https://doaj.org/article/ee290fbcb63e4bc0b0972c421252562e
Autor:
Jérémy Reverchon, Vianney Tuloup, Romain Garreau, Viviane Nave, Sabine Cohen, Philippe Reix, Stéphane Durupt, Raphaele Nove-Josserand, Isabelle Durieu, Quitterie Reynaud, Laurent Bourguignon, Sandrine Charles, Sylvain Goutelle
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1750 (2022)
Therapeutic drug monitoring (TDM) of tobramycin is widely performed in patients with cystic fibrosis (CF), but little is known about the value of model-informed precision dosing (MIPD) in this setting. We aim at reporting our experience with tobramyc
Externí odkaz:
https://doaj.org/article/19b12a936977453c959ea5cb2515bb98
Autor:
Charlotte Genestet, Elisabeth Hodille, Alexia Barbry, Jean-Luc Berland, Jonathan Hoffmann, Emilie Westeel, Fabiola Bastian, Michel Guichardant, Samuel Venner, Gérard Lina, Christophe Ginevra, Florence Ader, Sylvain Goutelle, Oana Dumitrescu
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009643 (2021)
Mycobacterium tuberculosis (Mtb) genetic micro-diversity in clinical isolates may underline mycobacterial adaptation to tuberculosis (TB) infection and provide insights to anti-TB treatment response and emergence of resistance. Herein we followed wit
Externí odkaz:
https://doaj.org/article/566cb6f4287b4394b2676e6bd8594c81
Autor:
Romain Guilhaumou, Sihem Benaboud, Youssef Bennis, Claire Dahyot-Fizelier, Eric Dailly, Peggy Gandia, Sylvain Goutelle, Sandrine Lefeuvre, Nicolas Mongardon, Claire Roger, Julien Scala-Bertola, Florian Lemaitre, Marc Garnier
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-20 (2019)
Abstract Background Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the intensive care unit (ICU). ICU patients present many pathophysiological features that cause pharmacokinetic (PK) and pharmacodynamic (PD) specificities,
Externí odkaz:
https://doaj.org/article/a95e4bbf19074fbd8efce22c8038c53a
Autor:
Sylvain Goutelle, Anne Conrad, Cécile Pouderoux, Evelyne Braun, Frédéric Laurent, Marie-Claude Gagnieu, Sabine Cohen, Jérôme Guitton, Florent Valour, Tristan Ferry
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Suppressive parenteral antibiotic therapy with beta-lactams may be necessary in patients with Gram-negative bone and joint infection (BJI). Subcutaneous drug administration can facilitate this therapy in outpatient setting, but there is limited infor
Externí odkaz:
https://doaj.org/article/26851b28bd2143f2839b1c0bb1b5bccc
Autor:
Anne-Lise Bienvenu, Pierre Pradat, Alexandra Plesa, Vincent Leclerc, Vincent Piriou, Jean-Luc Fellahi, Laurent Argaud, Thomas Rimmelé, Jean Menotti, Frédéric Aubrun, Jean-Christophe Richard, Marie-Claude Gagnieu, François Parant, Christian Chidiac, Gilles Leboucher, Michel Tod, Sylvain Goutelle
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260656 (2021)
Therapeutic drug monitoring (TDM) is essential for voriconazole to ensure optimal drug exposure, mainly in critically ill patients for whom voriconazole demonstrated a large variability. The study aimed at describing factors associated with trough vo
Externí odkaz:
https://doaj.org/article/cd0d8eced2204a44936cdb5b3a8cd8c5
Autor:
Tristan Ferry, Thomas P. Lodise, Jason C. Gallagher, Emmanuel Forestier, Sylvain Goutelle, Vincent H. Tam, John F. Mohr, Claire Roubaud-Baudron
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Since the 1970s, outpatient parenteral antimicrobial therapy (OPAT) has been a viable option for patients who require intravenous antibiotics when hospitalization is not warranted. While the benefits of OPAT as a measure to improve the efficiency of
Externí odkaz:
https://doaj.org/article/ddd81a920ca34ffd99790d7ba626a2e1