Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Sylvain Gandon"'
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002122 (2023)
Organisms have evolved a range of constitutive (always active) and inducible (elicited by parasites) defence mechanisms, but we have limited understanding of what drives the evolution of these orthogonal defence strategies. Bacteria and their phages
Externí odkaz:
https://doaj.org/article/ee9d75b08b8b4b6e99cbfded0f92bca0
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011602 (2023)
Phages are promising tools to fight antibiotic-resistant bacteria, and as for now, phage therapy is essentially performed in combination with antibiotics. Interestingly, combined treatments including phages and a wide range of antibiotics lead to an
Externí odkaz:
https://doaj.org/article/8591329391904bc28eaee74ea789faf9
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001804 (2022)
Following the initiation of the unprecedented global vaccination campaign against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), attention has now turned to the potential impact of this large-scale intervention on the evolution of the
Externí odkaz:
https://doaj.org/article/1676d7038ab245deb14ff1ce40146ad6
Autor:
David V McLeod, Sylvain Gandon
Publikováno v:
eLife, Vol 10 (2021)
The evolution of multidrug resistance (MDR) is a pressing public health concern. Yet many aspects, such as the role played by population structure, remain poorly understood. Here, we argue that studying MDR evolution by focusing upon the dynamical eq
Externí odkaz:
https://doaj.org/article/705c0c1285c04a439f753ea423728585
Publikováno v:
Evolution Letters, Vol 3, Iss 2, Pp 152-161 (2019)
Abstract The ability of the agent of plague, Yersinia pestis, to form a biofilm blocking the gut of the flea has been considered to be a key evolutionary step in maintaining flea‐borne transmission. However, blockage decreases dramatically the life
Externí odkaz:
https://doaj.org/article/6cdf1c039389411296e24947a5ea532a
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-6 (2019)
Abstract Background Some Plasmodium species have the ability to modify the behaviour of their mosquito vectors. This is thought to be an adaptive strategy that maximizes the parasite’s transmission. Methods The effect of Plasmodium relictum infecti
Externí odkaz:
https://doaj.org/article/e615bce33bd24dad929e8a85729b5722
Autor:
Bridget S Penman, Sylvain Gandon
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008181 (2020)
The mutation responsible for Duffy negativity, which impedes Plasmodium vivax infection, has reached high frequencies in certain human populations. Conversely, mutations capable of blocking the more lethal P. falciparum have not succeeded in malariou
Externí odkaz:
https://doaj.org/article/abe0a2f25fc54dd6be35bdb43812ce51
Autor:
Philippe Carmona, Sylvain Gandon
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 7, p e1007954 (2020)
Many infectious diseases exhibit seasonal dynamics driven by periodic fluctuations of the environment. Predicting the risk of pathogen emergence at different points in time is key for the development of effective public health strategies. Here we stu
Externí odkaz:
https://doaj.org/article/53545086977245f798874c9f83f8fa9e
Autor:
Hélène Chabas, Sébastien Lion, Antoine Nicot, Sean Meaden, Stineke van Houte, Sylvain Moineau, Lindi M Wahl, Edze R Westra, Sylvain Gandon
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2006738 (2018)
The emergence and re-emergence of pathogens remains a major public health concern. Unfortunately, when and where pathogens will (re-)emerge is notoriously difficult to predict, as the erratic nature of those events is reinforced by the stochastic nat
Externí odkaz:
https://doaj.org/article/54a86ab65d064ce1a8cf60aa3525630f
Autor:
Flore Zélé, Juilen Vézilier, Gregory L’Ambert, Antoine Nicot, Sylvain Gandon, Ana Rivero, Olivier Duron
Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-16 (2014)
Abstract Background Identifying the parasites transmitted by a particular vector and the factors that render this vector susceptible to the parasite are key steps to understanding disease transmission. Although avian malaria has become a model system
Externí odkaz:
https://doaj.org/article/e749d21253cd4f98ab54893cf325680e