Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Sylvain Fisson"'
Autor:
Juliette Pulman, Catherine Botto, Hugo Malki, Duohao Ren, Paul Oudin, Anne De Cian, Marie As, Charlotte Izabelle, Bruno Saubamea, Valerie Forster, Stéphane Fouquet, Camille Robert, Céline Portal, Aziz El-Amraoui, Sylvain Fisson, Jean-Paul Concordet, Deniz Dalkara
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102349- (2024)
Genome editing by CRISPR-Cas holds promise for the treatment of retinal dystrophies. For therapeutic gene editing, transient delivery of CRISPR-Cas9 is preferable to viral delivery which leads to long-term expression with potential adverse consequenc
Externí odkaz:
https://doaj.org/article/79b809bb916648639568bb98681ed82b
Autor:
Divya Ail, Duohao Ren, Elena Brazhnikova, Céline Nouvel-Jaillard, Stephane Bertin, Seyed Bagher Mirashrafi, Sylvain Fisson, Deniz Dalkara
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 306-316 (2022)
Positive clinical outcomes in adeno-associated virus (AAV)-mediated retinal gene therapy have often been attributed to the low immunogenicity of AAVs and immune privilege of the eye. However, several recent studies have shown potential for inflammato
Externí odkaz:
https://doaj.org/article/5f1307aa30894217bbe9ecb9a1d4feef
Publikováno v:
Cell Journal, Vol 22, Iss 4, Pp 548-555 (2021)
Objective: von Frey Filament (vFF) is an aesthesiometer to measure paw withdrawal thresholds. Our aim was to validate the manually von Frey test technique for assessing neuropathic pain behavioral signs in a sciatic nerve ligation model. Materials
Externí odkaz:
https://doaj.org/article/461c688ff50d41378037053f7367aff0
Autor:
Marie-Hélène Errera, Ana Pratas, Sylvain Fisson, Thomas Manicom, Marouane Boubaya, Neila Sedira, Emmanuel Héron, Lilia Merabet, Alfred Kobal, Vincent Levy, Jean-Michel Warnet, Christine Chaumeil, Françoise Brignole-Baudouin, José-Alain Sahel, Pablo Goldschmidt, Bahram Bodaghi, Coralie Bloch-Queyrat
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
To investigate which cytokines, chemokines and growth factors are involved in the immunopathogenesis of idiopathic uveitis, and whether cytokine profiles are associated with. Serum and aqueous humor (AH) samples of 75 patients with idiopathic uveitis
Externí odkaz:
https://doaj.org/article/a7f7d2f8e13149edbe967554f96c1b6f
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1973 (2022)
Inherited retinal diseases (IRDs) are a leading cause of blindness in industrialized countries, and gene therapy is quickly becoming a viable option to treat this group of diseases. Gene replacement using a viral vector has been successfully applied
Externí odkaz:
https://doaj.org/article/b0c127b7250e44f8bc55df7f7c285bc6
Publikováno v:
Romanian Journal of Neurology, Vol 18, Iss 3, Pp 127-136 (2019)
Background. Accumulating evidence illustrates that peripheral nerve injuries activate glial components of the peripheral and central cellular circuitry which contributes to neuroinflammation and neuropathic pain. Epidemiological surveys suggest that
Externí odkaz:
https://doaj.org/article/b765857f11e547d0b59c2df62c110238
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
PurposeInjection of an antigen into the anterior chamber of the eye induces a peripheral antigen-specific immune modulation mechanism, known as anterior chamber-associated immune deviation (ACAID). Delayed-type hypersensitivity experiments argue that
Externí odkaz:
https://doaj.org/article/b0f9413c9ac843eb9a4fb74dbc8d4bb8
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Anterior chamber-associated immune deviation (ACAID) is a well-known phenomenon that can occur after an antigen is introduced without any danger signal into the anterior chamber of a murine eye. It is reported to lead to an antigen-specific immune de
Externí odkaz:
https://doaj.org/article/0a0ce0f775134804bb899b1d7ced4844
Autor:
Séverine Ciré, Sylvie Da Rocha, Roseline Yao, Sylvain Fisson, Christian J Buchholz, Mary K Collins, Anne Galy
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101644 (2014)
Gene transfer vectors such as lentiviral vectors offer versatile possibilities to express transgenic antigens for vaccination purposes. However, viral vaccines leading to broad transduction and transgene expression in vivo, are undesirable. Therefore
Externí odkaz:
https://doaj.org/article/92971d21e25243fbbeac7990ed174be4
Autor:
Sylvain Fisson, Hanane Ouakrim, Valérie Touitou, Sylvie Baudet, Rym Ben Abdelwahed, Sabrina Donnou, Amine Miloudi, Claire Galand, Bahram Bodaghi, Phuc Lehoang, Martine Brissard, Magali Le Garff-Tavernier, Wolf Herman Fridman, Catherine Sautès-Fridman, Nathalie Cassoux, Hélène Merle-Béral
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e52385 (2013)
Primary intraocular lymphoma (PIOL), also called primary vitreoretinal lymphomas, often masquerades as uveitis. This misdiagnosis can result in subsequent brain involvement and oculocerebral lymphoma (OCL). In this study, we sought to characterize th
Externí odkaz:
https://doaj.org/article/7adf35df6ff3487a8fec1627ce284fb5