Ciguatoxins activate the Calcineurin signalling pathway in Yeasts: Potential for development of an alternative detection tool?

Autor: Christophe Furger, Dominique Laurent, Hélène Martin-Yken, Camille Gironde, Mireille Chinain, Sylvain Derick, Hélène Taiana Darius

Publikováno v: Environmental Research
Environmental Research, Elsevier, 2018, 162, pp.144-151. ⟨10.1016/j.envres.2017.12.022⟩
Environmental Research, 2018, 162, pp.144-151. ⟨10.1016/j.envres.2017.12.022⟩

International audience; Ciguatoxins (CTXs) are lipid-soluble polyether compounds produced by dinoflagellates from the genus Gambierdiscus spp. typically found in tropical and subtropical zones. This endemic area is however rapidly expanding due to en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ac3b86e5f9c0667b0b787357c8d38c
https://hal.archives-ouvertes.fr/hal-01680541

Functional and Pharmacological Characterization of the First Specific Agonist and Antagonist for the V1b Receptor in Mammals.

Autor: Gal Claudine, Serradeil-Le¹, Sylvain, Derick², Gabrielle, Brossard³, Maurice, Manning⁴, Jacques, Simiand³, Rolf, Gaillard⁵, Guy, Griebel¹, Gilles, Guillon² Giles.Guillon@ccipe.cnrs.fr

Publikováno v: Stress: The International Journal on the Biology of Stress. Sep2003, Vol. 6 Issue 3, p199-206. 8p. 1 Diagram, 1 Chart, 4 Graphs.

Design of Potent and Selective Agonists for the Human Vasopressin V1b Receptor Based on Modifications of [Deamino-Cys]arginine Vasopressin at Position 4

Autor: Maurice Manning, Stoytcho Stoev, Ana Pena, Ling Ling Cheng, Gilles Guillon, Mohamed Ben Mimoun, Sylvain Derick

Publikováno v: Journal of Medicinal Chemistry. 47:2375-2388

The glutamine4 residue in [deamino-Cys1]arginine vasopressin (dAVP) was replaced by a broad series of aliphatic, aromatic, polar, and charged amino acids to give the following peptides: d[Gly4]AVP (1), d[Ala4]AVP (2), d[Abu4]AVP (3), d[Nva4]AVP (4),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dae2f0e5c6129deeb652acbaccc96a1
https://doi.org/10.1021/jm030611c

Vasopressin Receptors in Human Adrenal Medulla and Pheochromocytoma1

Autor: Eric Grazzini, Gilles Guillon, G. Boccara, Pascal Colson, Sylvain Derick, Christophe Breton, Claudine Serradeil-Le Gal, Danièle Raufaste, Miriam Andrés, Nathalie C. Guérineau, Frédérique Rickwaert

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 84:2195-2203

The nature of vasopressin (VP) receptors present in normal and tumoral human adrenal was investigated using various experimental approaches. Specific VP-binding sites were detected by autoradiography using[ 3H]arginine VP as a radioligand in adrenal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea614c63ac21c53582a6e643cd31e4e4
https://doi.org/10.1210/jcem.84.6.5775

Collaborative study for the detection of toxic compounds in shellfish extracts using cell-based assays. Part I: screening strategy and pre-validation study with lipophilic marine toxins

Autor: Cécile Bernard, Rachelle Lanceleur, Marc Troussellier, Sophie Krys, Christophe Furger, Valérie Fessard, Elie Augier, Bénédicte Morin, Sahima Hamlaoui, Ronel Biré, Serge Moukha, Anne-Laure Sérandour, Sylvain Derick, Aurélie Ledreux

Publikováno v: Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, Springer Verlag, 2012, 403 (inpress), epub ahead of print. ⟨10.1007/s00216-012-6028-1⟩
Analytical and Bioanalytical Chemistry, Springer Verlag, 2012, epub ahead of print. ⟨10.1007/s00216-012-6028-1⟩

Human poisoning due to consumption of seafood contaminated with phycotoxins is a worldwide problem, and routine monitoring programs have been implemented in various countries to protect human consumers. Following successive episodes of unexplained sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f5a7aebee0b4be9747137f95608bb2
https://hal-anses.archives-ouvertes.fr/hal-00694974