Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Sylvain Brunet"'
Autor:
Selva Baltan, Ursula S. Sandau, Sylvain Brunet, Chinthasagar Bastian, Ajai Tripathi, Hung Nguyen, Helen Liu, Julie A. Saugstad, Yalda Zarnegarnia, Ranjan Dutta
Publikováno v:
ASN Neuro, Vol 13 (2021)
We have previously shown that two anti-cancer drugs, CX-4945 and MS-275, protect and preserve white matter (WM) architecture and improve functional recovery in a model of WM ischemic injury. While both compounds promote recovery, CX-4945 is a selecti
Externí odkaz:
https://doaj.org/article/6b00cc6c2c294f509a17ea54ec8da44b
Autor:
Chinthasagar Bastian, John Quinn, Ajai Tripathi, Danielle Aquila, Andrew McCray, Ranjan Dutta, Selva Baltan, Sylvain Brunet
Publikováno v:
Neurobiology of Disease, Vol 126, Iss , Pp 47-61 (2019)
White matter (WM) is injured in most strokes, which contributes to functional deficits during recovery. Casein kinase 2 (CK2) is a protein kinase that is expressed in brain, including WM. To assess the impact of CK2 inhibition on axon recovery follow
Externí odkaz:
https://doaj.org/article/caa8556cc7ef42b7871fb63ec639f777
Autor:
Masahiro Hitomi, Loic P. Deleyrolle, Erin E. Mulkearns-Hubert, Awad Jarrar, Meizhang Li, Maksim Sinyuk, Balint Otvos, Sylvain Brunet, William A. Flavahan, Christopher G. Hubert, Winston Goan, James S. Hale, Alvaro G. Alvarado, Ao Zhang, Mark Rohaus, Muna Oli, Vinata Vedam-Mai, Jeff M. Fortin, Hunter S. Futch, Benjamin Griffith, Qiulian Wu, Chun-hong Xia, Xiaohua Gong, Manmeet S. Ahluwalia, Jeremy N. Rich, Brent A. Reynolds, Justin D. Lathia
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 1031-1042 (2015)
The coordination of complex tumor processes requires cells to rapidly modify their phenotype and is achieved by direct cell-cell communication through gap junction channels composed of connexins. Previous reports have suggested that gap junctions are
Externí odkaz:
https://doaj.org/article/494a4a229a984f468e7f3e93cceb546e
Autor:
Sylvain Brunet, Yalda Zarnegarnia, Ajai K. Tripathi, Julie A. Saugstad, Chinthasagar Bastian, Ranjan Dutta, Selva Baltan, Helen Liu, Ursula S. Sandau, Hung Nguyen
Publikováno v:
ASN Neuro, Vol 13 (2021)
ASN NEURO
ASN NEURO
We have previously shown that two anti-cancer drugs, CX-4945 and MS-275, protect and preserve white matter (WM) architecture and improve functional recovery in a model of WM ischemic injury. While both compounds promote recovery, CX-4945 is a selecti
Autor:
Andrew McCray, Chinthasagar Bastian, Selva Baltan, Sylvain Brunet, John Quinn, Danielle Aquila
Publikováno v:
Neurosci Lett
Strokes occur predominantly in the elderly and white matter (WM) is injured in most strokes, contributing to the disability associated with clinical deficits. Casein kinase 2 (CK2) is expressed in neuronal cells and was reported to be neuroprotective
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2143
The use of ex vivo compound action potential (CAP) recordings from intact optic nerves is an ideal model to study white matter function without the influence of gray matter. Here, we describe how freshly dissected optic nerves are placed in a humidif
Autor:
Chinthasagar, Bastian, John, Quinn, Christine, Doherty, Caroline, Franke, Anna, Faris, Sylvain, Brunet, Selva, Baltan
Publikováno v:
Advances in neurobiology. 23
The astrocyte-neuron lactate transfer shuttle (ANLS) is one of the important metabolic systems that provides a physiological infrastructure for glia-neuronal interactions where specialized architectural organization supports the function. Perivascula
Autor:
Sylvain Brunet, Chinthasagar Bastian, Xinhua Yin, Riqiang Yan, Bruce D. Trapp, Xiangyou Hu, Grahame J. Kidd, Hailong Hou, Wanxia He, Selva Baltan, Shupeng Qiu, Yingying Ge
Publikováno v:
Glia. 65:712-726
BACE1 is an indispensable enzyme for generating β-amyloid peptides, which are excessively accumulated in brains of Alzheimer's patients. However, BACE1 is also required for proper myelination of peripheral nerves, as BACE1-null mice display hypomyel
Publikováno v:
Neuromolecular Med
Stroke significantly affects white matter in the brain by impairing axon function, which results in clinical deficits. Axonal mitochondria are highly dynamic and are transported via microtubules in the anterograde or retrograde direction, depending u
Autor:
John Quinn, Chinthasagar Bastian, Selva Baltan, Caroline Franke, Sylvain Brunet, Christine Doherty, Anna Faris
Publikováno v:
Advances in Neurobiology ISBN: 9783030274795
The astrocyte-neuron lactate transfer shuttle (ANLS) is one of the important metabolic systems that provides a physiological infrastructure for glia-neuronal interactions where specialized architectural organization supports the function. Perivascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a8c382e4ba0cc5d4367d5a6888dc53
https://doi.org/10.1007/978-3-030-27480-1_12
https://doi.org/10.1007/978-3-030-27480-1_12