Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sylvain Bordeleau"'
Autor:
Rebekah J. Carson, Sylvain Bordeleau, Michael J. Little, Pierre L. Beaulieu, Steven R. LaPlante, Jeff A. O'Meara, James Gillard, Pierre R. Bonneau, Norman Aubry, René Coulombe
Publikováno v:
Journal of Medicinal Chemistry. 56:5142-5150
The pharmaceutical industry has recognized that many drug-like molecules can self-aggregate in aqueous media and have physicochemical properties that skew experimental results and decisions. Herein, we introduce the use of a simple NMR strategy for d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c46e3b04d4fadd8413968aa1097917c
https://doi.org/10.1021/jm400535b
https://doi.org/10.1021/jm400535b
Autor:
Léa Constantineau Forget, Cyrille Kuhn, Vida Gorys, Colette Boucher, Chantal Grand-Maître, Sylvain Bordeleau, Michael J. Little, Christian Brochu, Tim Guo, Marc Pesant, Michel Garneau, Megan Bertrand-Laperle, Catherine Spickler, Gulrez Fazal, Pascal Turcotte, Annick Gauthier, Eric Malenfant, Josée Bordeleau, Anne Decor, Jeff A. O'Meara, Ghiro Elise, Oliver Hucke
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(13)
We describe here the design, synthesis and biological evaluation of antiviral compounds acting against human rhinovirus (HRV). A series of aminothiazoles demonstrated pan-activity against the HRV genotypes screened and productive structure-activity r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e726058fc98e111b0fb3232d10f1f5ba
https://pubmed.ncbi.nlm.nih.gov/23726345
https://pubmed.ncbi.nlm.nih.gov/23726345