Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Sylvain Baruchel"'
Autor:
Sushil Kumar, Jessica D. Sun, Libo Zhang, Reza Bayat Mokhtari, Bing Wu, Fanying Meng, Qian Liu, Deepthi Bhupathi, Yan Wang, Herman Yeger, Charles Hart, Sylvain Baruchel
Publikováno v:
Translational Oncology, Vol 11, Iss 4, Pp 911-919 (2018)
Antiangiogenic therapy has shown promising results in preclinical and clinical trials. However, tumor cells acquire resistance to this therapy by gaining ability to survive and proliferate under hypoxia induced by antiangiogenic therapy. Combining an
Externí odkaz:
https://doaj.org/article/b8d0cf9939e1467aaede794a5eb26ac2
Publikováno v:
Translational Oncology, Vol 10, Iss 4, Pp 604-611 (2017)
BACKGROUND: Anaplastic lymphoma kinase (ALK) inhibitor crizotinib has proven to be effective in the treatment of ALK-mutated neuroblastoma, but crizotinib resistance was commonly observed in patients. We aimed to overcome crizotinib resistance by com
Externí odkaz:
https://doaj.org/article/730732b4dded43938165e5d558ec6083
Autor:
Kelly R. McMahon, Shahrad Rod Rassekh, Kirk R. Schultz, Maury Pinsk, Tom Blydt-Hansen, Cherry Mammen, Ross T. Tsuyuki, Prasad Devarajan, Geoff D. E. Cuvelier, Lesley G. Mitchell, Sylvain Baruchel, Ana Palijan, Bruce C. Carleton, Colin J. D. Ross, Michael Zappitelli
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 4 (2017)
Background: Childhood cancer survivors experience adverse drug events leading to lifelong health issues. The Applying Biomarkers to Minimize Long-Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) team was established to validate and apply
Externí odkaz:
https://doaj.org/article/32e16016fb1a4c4bb457e5058139481e
Autor:
Libo Zhang, Kristen M. Smith, Amy Lee Chong, Diana Stempak, Herman Yeger, Paula Marrano, Paul S. Thorner, Meredith S. Irwin, David R. Kaplan, Sylvain Baruchel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 5, Pp 426-435 (2009)
Neuroblastoma (NB) is one of the most common pediatric solid tumors originating from the neural crest lineage. Despite intensive treatment protocols including megatherapy with hematopoietic stem cell transplantation, the prognosis of NB patients rema
Externí odkaz:
https://doaj.org/article/4faecf779bcd4660b737eff0c7b3940e
Autor:
Bikul Das, Roula Antoon, Rika Tsuchida, Shamim Lotfi, Olena Morozova, Walid Farhat, David Malkin, Gideon Koren, Herman Yeger, Sylvain Baruchel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 10, Pp 1105-1119 (2008)
Squalene, an isoprenoid antioxidant is a potential cytoprotective agent against chemotherapy-induced toxicity. We have previously published that squalene protects light-density bone marrow cells against cis-diamminedichloroplatinum( II) (cisplatin)-i
Externí odkaz:
https://doaj.org/article/071dccd5592e4e12b0d84713c5a4b361
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 1, Pp 36-46 (2007)
Neuroblastoma (NB) is derived from intrinsic migratory neural crest cells and has a high potential for distant metastasis. Growing evidence has implicated chemokine receptors, especially CXCR4, which normally control immune and inflammatory cell migr
Externí odkaz:
https://doaj.org/article/ee96965593aa40bb864a76cb338d7c7e
Publikováno v:
International Journal of Qualitative Methods, Vol 5 (2006)
When conducting photo elicitation interviews (PEI), researchers introduce photographs into the interview context. Although PEI has been employed across a wide variety of disciplines and participants, little has been written about the use of photograp
Externí odkaz:
https://doaj.org/article/152862dd37fb455f8d34c85be2056529
Purpose: Tumor cells residing in tumor hypoxic zones are a major cause of drug resistance and tumor relapse. In this study, we investigated the efficacy of evofosfamide, a hypoxia-activated prodrug, and its combination with topotecan in neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07351508b4508668b5075a69348822d4
https://doi.org/10.1158/1078-0432.c.6523467
https://doi.org/10.1158/1078-0432.c.6523467
Limited anti-tumor effects of ifosfamide in the CHLA-20 xenograft model. A total of 1 Ã- 106 CHLA-20 cells were implanted subcutaneously into SCID/SCID mice. Once tumors were palpable (about 0.25cm3), mice were randomized into vehicle control (n=6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a071d7a0b6c691b6454e89df746e4da
https://doi.org/10.1158/1078-0432.22456971.v1
https://doi.org/10.1158/1078-0432.22456971.v1