Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Sylvain, Perruche"'
Autor:
Thierry Gauthier, Omayra Martin-Rodriguez, Cécile Chagué, Anna Daoui, Adam Ceroi, Alexis Varin, Francis Bonnefoy, Séverine Valmary-Degano, Mélanie Couturier, Susanne Behlke, Philippe Saas, Pierre-François Cartron, Sylvain Perruche
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Reinstating inflammation resolution represents an innovative concept to regain inflammation control in diseases marked by chronic inflammation. While most therapeutics target inflammatory molecules and inflammatory effector cells
Externí odkaz:
https://doaj.org/article/ff55f83d61f749b3983efca034044231
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Several chronic inflammatory diseases are associated with non-resolving inflammation. Conventional anti-inflammatory drugs fail to completely cure these diseases. Resolution pharmacology is a new therapeutic approach based on the use of pro-resolving
Externí odkaz:
https://doaj.org/article/49d134566c0441a98be7714a2fec9ded
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/4d99ea48bc724ea29226774ed1f41f61
Autor:
Audrey Wetzel, Francis Bonnefoy, Cécile Chagué, Mathieu Vetter, Mélanie Couturier, Blandine Baffert, Olivier Adotévi, Philippe Saas, Sylvain Perruche
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Cancers are consequences of cellular dysfunction leading to an aberrant cellular multiplication and proliferation, subsequently yielding metastasis formation. Inflammatory reaction, with immune cell recruitment, is the main defense against precancero
Externí odkaz:
https://doaj.org/article/0fbbf3ab40294c698513f236f819d73b
Autor:
Omayra Martin-Rodriguez, Thierry Gauthier, Francis Bonnefoy, Mélanie Couturier, Anna Daoui, Cécile Chagué, Séverine Valmary-Degano, Claire Gay, Philippe Saas, Sylvain Perruche
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Nonresolving inflammation is a critical driver of several chronic inflammatory diseases, including inflammatory bowel diseases (IBD). This unresolved inflammation may result from the persistence of an initiating stimulus or from the alteration of the
Externí odkaz:
https://doaj.org/article/0aceeb52c9d44511b1067adf0daf7a7d
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Both the initiation and the resolution of inflammatory responses are governed by the sequential activation, migration, and control/suppression of immune cells at the site of injury. Bioactive lipids play a major role in the fine-tuning of this dynami
Externí odkaz:
https://doaj.org/article/8c9b52be948d4ead82a8151922b16622
Autor:
Céline Coppard, Francis Bonnefoy, Dalil Hannani, Françoise Gabert, Olivier Manches, Joel Plumas, Sylvain Perruche, Laurence Chaperot
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Despite major advances in rheumatoid arthritis outcome, not all patients achieve remission, and there is still an unmet need for new therapeutic approaches. This study aimed at evaluating in a pre-clinical murine model the efficac
Externí odkaz:
https://doaj.org/article/3a25a8eec97c49d0b2f3120b20cdd405
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Rheumatoid arthritis (RA) is a chronic immune-mediated disease managed by conventional synthetic drugs, such as methotrexate (MTX), and targeted drugs including biological agents. Cell-based therapeutic approaches are currently developed in RA, mainl
Externí odkaz:
https://doaj.org/article/c67d15b7e56443b79d05fe3dacd7de5e
Autor:
Francis Bonnefoy, Thierry Gauthier, Romain Vallion, Omayra Martin-Rodriguez, Anais Missey, Anna Daoui, Séverine Valmary-Degano, Philippe Saas, Mélanie Couturier, Sylvain Perruche
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Unresolved inflammation is a common feature in the pathogenesis of chronic inflammatory/autoimmune diseases. The factors produced by macrophages eliminating apoptotic cells during resolution are crucial to terminate inflammation, and for subsequent t
Externí odkaz:
https://doaj.org/article/be799b3bb92044b480c1aadd98c26651
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Early-stage apoptotic cells possess immunomodulatory properties. Proper apoptotic cell clearance during homeostasis has been shown to limit subsequent immune responses. Based on these observations, early-stage apoptotic cell infusion has been used to
Externí odkaz:
https://doaj.org/article/0a671b27008c4502a6e0adc4d8a48679