Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Sylvain, Ladoire"'
Autor:
Neree Payan, Benoit Presles, Charles Coutant, Isabelle Desmoulins, Sylvain Ladoire, Françoise Beltjens, François Brunotte, Jean-Marc Vrigneaud, Alexandre Cochet
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background: The aim of this study is to investigate the added value of combining tumour blood flow (BF) and metabolism parameters, including texture features, with clinical parameters to predict, at baseline, the pathological complete respon
Externí odkaz:
https://doaj.org/article/c9ec157b39b2468e84ff3d4667dfdc97
Autor:
Sylvain Ladoire, Ariane Mamguem Kamga, Loick Galland, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Mihaelia Ilie, Audrey Hennequin, Clementine Jankowski, Juliette Albuisson, Sophie Nambot, Charles Coutant, Laurent Arnould, Manon Reda, Caroline Truntzer, Sandrine Dabakuyo
Publikováno v:
Breast, Vol 78, Iss , Pp 103789- (2024)
Background: The results of the OlympiA study led to the approval of a PARP inhibitor (olaparib) as adjuvant treatment for early breast cancer (eBC) at high risk of relapse in patients with a germline BRCA1/2 mutation (gBRCAm). However, the proportion
Externí odkaz:
https://doaj.org/article/b67a5194fa204825b8518e79deea3b8e
Autor:
Nicolas Roussot, Marion Thibaudin, Jean-David Fumet, Susy Daumoine, Léa Hampe, Cédric Rébé, Emeric Limagne, Aurélie Lagrange, Victor Herreros, Julie Lecuelle, Hugo Mananet, Alis Ilie, David Rageot, Romain Boidot, Vincent Goussot, Anthony Comte, Pierre Jacob, Françoise Beltjens, Anthony Bergeron, Céline Charon-Barra, Laurent Arnould, Valentin Derangère, Sylvain Ladoire, Caroline Truntzer, François Ghiringhelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
A patient with a PD-L1-negative, TMB-low, KEAP1/STK11 co-mutated metastatic non-small cell lung cancer (NSCLC) experienced a multisite radiological progression at 3 months after initiation of chemoimmunotherapy as first-line treatment for metastatic
Externí odkaz:
https://doaj.org/article/720f9ebdb12b41d5a9b653e489118e2d
Autor:
Alexandre de Moura, Perrine Vuagnat, Benjamin Renouf, Jean-Yves Pierga, Delphine Loirat, Pauline Vaflard, Charline Lafayolle de la Bruyère, Natacha Chaumard-Billotey, Nawale Hajjaji, Sylvain Ladoire, Sandrine Dabakuyo, Anne Patsouris, Jean Sébastien Frenel, Vincent Nicolai, Marie Alexandre, Nadine Dohollou, Julien Grenier, Heloïse Bourien, François-Clément Bidard
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Following the results of the IMpassion130 trial, an early access program (EAP) was opened in France, allowing patients with PD-L1-positive advanced triple negative breast cancer (aTNBC) to receive a combination of paclitaxel and atezolizumab
Externí odkaz:
https://doaj.org/article/32a11dfa386a4c37a6ba7f6ce998b444
Autor:
Jérémy Baude, Caroline Guigou, David Thibouw, Noémie Vulquin, Mireille Folia, Guillaume Constantin, Jihane Boustani, Christian Duvillard, Sylvain Ladoire, Gilles Truc, Aurélie Bertaut, Cédric Chevalier
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307658 (2024)
BackgroundThe treatment of stage I-III HPV+ oropharyngeal squamous cell carcinoma (HPV-OPSCC) is based on either surgery ± adjuvant therapy or exclusive radio±chemotherapy. We sought to compare these two therapeutic strategies in terms of efficacy,
Externí odkaz:
https://doaj.org/article/4f52608fde9c48bc9a191af180f7bed2
Autor:
Silvia Mihaela Ilie, Nathalie Briot, Guillaume Constatin, Alis Ilie, Francoise Beltjens, Sylvain Ladoire, Isabelle Desmoulins, Audrey Hennequin, Aurelie Bertaut, Charles Coutant, Sylvain Causeret, Niama Ghozali, Bruno Coudert, Laurent Arnould
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundThe persistence of residual tumour after neoadjuvant chemotherapy (NAC) in localised triple-negative breast cancer (TNBC) is known to have a negative prognostic value. However, different degrees of expression of some immunohistochemical mar
Externí odkaz:
https://doaj.org/article/5f0054ccd4204d3ba672b7ef8f850799
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The detection of tumour gene mutations by DNA or RNA sequencing is crucial for the prescription of effective targeted therapies. Recent developments showed promising results for tumoral mutational status prediction using new deep learning ba
Externí odkaz:
https://doaj.org/article/d38070a7f6a04daf870471a42a6e9f4b
Autor:
Manon Réda, Anaïs Fouquier, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Ilie, Audrey Hennequin, Bruno Coudert, Aurélie Bertaut, Sylvain Ladoire
Publikováno v:
Breast, Vol 68, Iss , Pp 149-156 (2023)
Background: Taxanes are major drugs for metastatic breast cancer (MBC) treatment, and are generally well tolerated, making them attractive for therapeutic reintroduction (rechallenge) during metastatic course. In view of the paucity of current litera
Externí odkaz:
https://doaj.org/article/d2c8a36ac89a4f8b968b3b3f7d9ac24f
Autor:
Zoé Tharin, Corentin Richard, Valentin Derangère, Alis Ilie, Laurent Arnould, François Ghiringhelli, Romain Boidot, Sylvain Ladoire
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract There is little data concerning the implications of PIK3CA mutations outside of the known hotspots described in ER+/HER2− metastatic breast cancer (mBC). Similarly, PIK3R1 mutations could also lead to activation of PI3K pathway, but are po
Externí odkaz:
https://doaj.org/article/549ad5585730463788e76a11767d4dba
Autor:
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Ilie, Audrey Hennequin, Anthony Bergeron, Valentin Derangère, François Ghiringhelli, Caroline Truntzer, Sylvain Ladoire
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-16 (2022)
Abstract Purpose The vast majority of research studies that have described the links between DNA damage repair or homologous recombination deficiency (HRD) score, and tumor biology, have concerned either triple negative breast cancers or cancers with
Externí odkaz:
https://doaj.org/article/aae1a74ab7764d138f14f99a0499bf34