Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sylvain, Fieux"'
Autor:
Matthieu Colom, Benjamin Vidal, Sylvain Fieux, Jérôme Redoute, Nicolas Costes, Franck Lavenne, Inés Mérida, Zacharie Irace, Thibaud Iecker, Caroline Bouillot, Thierry Billard, Adrian Newman-Tancredi, Luc Zimmer
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
IntroductionSerotonin is involved in a variety of physiological functions and brain disorders. In this context, efforts have been made to investigate the in vivo fluctuations of this neurotransmitter using positron emission tomography (PET) imaging p
Externí odkaz:
https://doaj.org/article/191ab2b523a242d4b75c9265f7132537
Autor:
Véronique Sgambato-Faure, Thierry Billard, Elise Météreau, Sandra Duperrier, Sylvain Fieux, Nicolas Costes, Léon Tremblay, Luc Zimmer
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Brain serotonin-6 receptor (5-HT6R) is the one of the most recently identified serotonin receptors. Accumulating evidence suggests that it is a potent therapeutic target for psychiatric and neurological diseases. Since [18F]2FNQ1P was recently propos
Externí odkaz:
https://doaj.org/article/e7dc34cfcd90462aa22c95cde1c49215
Autor:
Laure Balasse, Julia Maerk, Frédéric Pain, Aurelie Genoux, Sylvain Fieux, Françoise Lefebvre, Christian Morel, Pascale Gisquet-Verrier, Philippe Lanièce, Luc Zimmer
Publikováno v:
Molecular Imaging, Vol 14 (2015)
The aim of this study was to demonstrate the potential of a wireless pixelated β+-sensitive intracerebral probe (PIXSIC) for in vivo positron emission tomographic (PET) radiopharmacology in awake and freely moving rodents. The binding of [ 11 C]racl
Externí odkaz:
https://doaj.org/article/bd605371fd544075b1bf4e9c63bb301e
Autor:
Stéphane Emery, Sylvain Fieux, Luc Zimmer, Benjamin Vidal, Adrian Newman-Tancredi, Elise Levigoureux, Caroline Bouillot
Publikováno v:
ACS Chemical Neuroscience
ACS Chemical Neuroscience, American Chemical Society (ACS), 2019, 10 (7), pp.3108-3119. ⟨10.1021/acschemneuro.8b00584⟩
ACS Chemical Neuroscience, American Chemical Society (ACS), 2019, 10 (7), pp.3108-3119. ⟨10.1021/acschemneuro.8b00584⟩
International audience; Serotonin 5-HT1A receptors constitute an attractive therapeutic target for various psychiatric or neurodegenerative disorders. These receptors are expressed in multiple brain regions on different neuronal populations and can b
Autor:
Thibaut Iecker, Benjamin Vidal, Christian Tourvieille, Sandrine Bouvard, Sylvain Fieux, Pierre Courault, Stéphane Emery, Thierry Billard, Luc Zimmer, Sophie Lancelot
Publikováno v:
Nuclear Medicine and Biology
Nuclear Medicine and Biology, Elsevier, 2020, 82-83, pp.57-63. ⟨10.1016/j.nucmedbio.2020.01.006⟩
Nuclear Medicine and Biology, 2020, 82-83, pp.57-63. ⟨10.1016/j.nucmedbio.2020.01.006⟩
Nuclear Medicine and Biology, Elsevier, 2020, 82-83, pp.57-63. ⟨10.1016/j.nucmedbio.2020.01.006⟩
Nuclear Medicine and Biology, 2020, 82-83, pp.57-63. ⟨10.1016/j.nucmedbio.2020.01.006⟩
Introduction The aim of this study was to perform in-vitro and in-vivo radiopharmacological characterizations of [ 18 F]2FNQ1P, a new PET radiotracer of 5-HT6 receptors, in rat, pig, non-human primate and human tissues. The 5-HT6 receptor is one of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409d10d701e32ebd464df4fd7402b4a7
https://hal.archives-ouvertes.fr/hal-03035781
https://hal.archives-ouvertes.fr/hal-03035781
Autor:
Stéphane, Emery, Sylvain, Fieux, Benjamin, Vidal, Pierre, Courault, Sandrine, Bouvard, Christian, Tourvieille, Thibaut, Iecker, Thierry, Billard, Luc, Zimmer, Sophie, Lancelot
Publikováno v:
Nuclear medicine and biology.
The aim of this study was to perform in-vitro and in-vivo radiopharmacological characterizations of [In-vitro autoradiography and saturation binding assays were performed in postmortem brain tissues from rat, pig, non-human primate and human caudate
Autor:
Jérôme Redouté, Sylvain Fieux, Nicolas Costes, Marjorie Villien, Frédéric Bonnefoi, Didier Le Bars, Adrian Newman-Tancredi, Luc Zimmer, Benjamin Vidal
Publikováno v:
Neuropsychopharmacology
Neuropsychopharmacology, Nature Publishing Group, 2018, 43 (11), pp.2310-2319. ⟨10.1038/s41386-018-0145-2⟩
Neuropsychopharmacology, Nature Publishing Group, 2018, 43 (11), pp.2310-2319. ⟨10.1038/s41386-018-0145-2⟩
International audience; In neuropharmacology, the recent concept of 'biased agonism' denotes the capacity of certain agonists to target-specific intracellular pathways of a given receptor in specific brain areas. In the context of serotonin pharmacot
Autor:
Nicolas Costes, Gabriel Kocevar, Sandrine Bouvard, Radu Bolbos, Jean-Baptiste Langlois, Laurent Bezin, C Bonnet, Luc Zimmer, J. Yankam Njiwa, Elise Levigoureux, Claudio Stamile, Guillaume Becker, Caroline Bouillot, Sylvain Fieux, Alexander Hammers
Publikováno v:
Yankam Njiwa, J, Costes, N, Bouillot, C, Bouvard, S, Fieux, S, Becker, G, Levigoureux, E, Kocevar, G, Stamile, C, Langlois, J B, Bolbos, R, Bonnet, C, Bezin, L, Zimmer, L & Hammers, A 2016, ' Quantitative longitudinal imaging of activated microglia as a marker of inflammation in the pilocarpine rat model of epilepsy using [11C]-(R)-PK11195 PET and MRI ', Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism . https://doi.org/10.1177/0271678X16653615
Journal of Cerebral Blood Flow and Metabolism
Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2017, 37 (4), pp.1251-1263. ⟨10.1177/0271678X16653615⟩
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (4), pp.1251-1263. ⟨10.1177/0271678X16653615⟩
Journal of Cerebral Blood Flow and Metabolism
Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2017, 37 (4), pp.1251-1263. ⟨10.1177/0271678X16653615⟩
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (4), pp.1251-1263. ⟨10.1177/0271678X16653615⟩
Inflammation may play a role in the development of epilepsy after brain insults. [11C]-( R)-PK11195 binds to TSPO, expressed by activated microglia. We quantified [11C]-( R)-PK11195 binding during epileptogenesis after pilocarpine-induced status epil
Autor:
Benjamin Vidal, Caroline Bouillot, Gilles Tamagnan, Luc Zimmer, Olivier Barret, Matthieu Colom, Sylvain Fieux, Adrian Newman-Tancredi, Cristian Constantinescu, Thierry Billard
Publikováno v:
Brain Structure and Function
Brain Structure and Function, Springer Verlag, 2018, 223 (6), pp.2973-2988. ⟨10.1007/s00429-018-1672-7⟩
Brain Structure and Function, Springer Verlag, 2018, 223 (6), pp.2973-2988. ⟨10.1007/s00429-018-1672-7⟩
Serotonin 1A receptors are known to play an important role in many psychiatric and neurodegenerative disorders. Currently, all available 5-HT1A receptor PET radiopharmaceuticals that are radiolabeled with fluorine-18 are antagonists. As agonists bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9925598525671409748d72194a445f60
https://hal-udl.archives-ouvertes.fr/hal-02107028
https://hal-udl.archives-ouvertes.fr/hal-02107028
Autor:
Frédéric Pain, L. Ammour, P. Laniece, Luc Zimmer, M. Kachel, P. Pangaud, G. Bertolone, J. Baudot, M. Goffe, F. Lefebvre, M.-A. Verdier, Andrei Dorokhov, L. Pinot, M. Bautista, Christine Hu-Guo, P. Gisquet, Marc Winter, Sylvain Fieux, Christian Morel, F. Gensolen, J. Heymes
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Nucl.Instrum.Meth.A A
Nucl.Instrum.Meth.A A, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Elsevier, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Nucl.Instrum.Meth.A A
Nucl.Instrum.Meth.A A, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Elsevier, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
IMIC is a Monolithic Active Pixel Sensor prototype designed for the MAPSSIC project, which aims at developing wireless intracerebral probes dedicated to image positron-emitting source activity in the brain of awake and freely moving rats. Former expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab22eee1294cb1f22d00de72500a307
https://hal.science/hal-01952201/document
https://hal.science/hal-01952201/document