Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sylke Kaltenhäuser"'
Autor:
Christoph Baerwald, Sybille Arnold, Matthias Pierer, Sylke Kaltenhäuser, Holm Häntzschel, M. Kamprad, Ulf Wagner
Publikováno v:
Rheumatology. 46:100-104
Objective To evaluate antibodies against cyclic citrullinated peptide (anti-CCP antibodies) for their predictive value for severe joint destruction in rheumatoid arthritis (RA) and to examine their relationship to shared epitope (SE)-positive DRB1 al
Autor:
Holm Häntzschel, Matthias Pierer, Ulf Wagner, Falk Moritz, Sylke Kaltenhäuser, Matthias Wahle
Publikováno v:
The Journal of Immunology. 173:2825-2833
The systemic CD4+ T cell compartment in patients with rheumatoid arthritis (RA) is characterized by TCR repertoire contraction, shortened telomere lengths, and decreased numbers of recent thymic emigrants, suggesting a disturbed CD4+ T cell homeostas
Autor:
Christoph Baerwald, Sybille Arnold, Manuela Rossol, Matthias Pierer, Holm Häntzschel, Ulf Wagner, Sylke Kaltenhäuser
Publikováno v:
Rheumatology international. 31(8)
Clonal expansions of autoreactive CD4+ T cells are frequently present in patients with rheumatoid arthritis (RA) and are stable over long periods of time. This study was undertaken to investigate the influence of anti-TNFα treatment on such clonal e
Autor:
Ulf Wagner, Sunna Hauschildt, Matthias Pierer, Manuela Rossol, Holm Häntzschel, Undine Meusch, Sylke Kaltenhäuser
Publikováno v:
Scopus-Elsevier
Monocytes and monocytic cells produce proinflammatory cytokines upon direct cell contact with activated T cells. In the autoimmune disease rheumatoid arthritis, the pivotal role of TNF-α implies that the interaction between transmembrane TNF-α (mTN
Autor:
M. Tröltzsch, W. Seidel, Sylke Kaltenhäuser, R. Wassmuth, Holm Häntzschel, Matthias Pierer, J. R. Kalden, Ulf Wagner
Publikováno v:
Rheumatology (Oxford, England). 42(4)
Objective. To evaluate the differential impact of HLA-DR and -DQ on the progression of erosive disease in the clinical course of early rheumatoid arthritis (RA). Methods. HLA genotyping for HLA-DR and -DQ was carried out in a prospective study of 87
Autor:
Sybille Arnold, Holm Häntzschel, Matthias Pierer, Sylke Kaltenhäuser, Ulf Wagner, W. Seidel, Bernd Wilke
Publikováno v:
European journal of immunology. 33(1)
Clonally expanded, autoreactive CD4(+)CD28(null) cells can be found in the peripheral blood of patients with rheumatoid arthritis and have been shown to be associated with severeextra-articular disease manifestations. We investigated the size of the
Autor:
Sybille Arnold, Sylke Kaltenhäuser, Matthias Pierer, Ulf Wagner, Bernd Wilke, Holm Häntzschel
Publikováno v:
Arthritis Research
Aim of the study was the analysis of systemic B cell activity and of the size of the B lymphocyte compartment in patients with rheumatoid arthritis (RA)
Autor:
Joachim R. Kalden, Ulf Wagner, Ralf Wassmuth, Sylke Kaltenhäuser, Markus Löffler, W. Seidel, Holm Häntzschel, Ernst Schuster, Sybille Arnold, Michael Tröltsch
Publikováno v:
Arthritis Research
Autor:
Heidemarie Sauer, Sybille Arnold, Ralf Wassmuth, Sylke Kaltenhäuser, W. Seidel, Joachim R. Kalden, Ulf Wagner, Holm Häntzschel
Publikováno v:
Arthritis and rheumatism. 40(2)
Objective. To evaluate HLA markers as early prognostic factors for disease severity in rheumatoid arthritis (RA). Methods. HLA genotyping was carried out in a retrospective analysis of 66 RA patients and in a prospective study of 55 RA patients and 8
Publikováno v:
Electrophoresis. 17(3)
IgG galactosylation deficiency in patients with rheumatoid arthritis (RA) can be detected by isoelectric focusing (IEF)/lectin affinoblotting. We analyzed IgG glycosylation in patients with early arthritis (n = 50) and healthy controls in order to de