Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sylke, Hoehnel"'
Autor:
Claire Simonneau, Martina Duschmalé, Alina Gavrilov, Nathalie Brandenberg, Sylke Hoehnel, Camilla Ceroni, Evodie Lassalle, Elena Kassianidou, Hendrik Knoetgen, Jens Niewoehner, Roberto Villaseñor
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background The pathways that control protein transport across the blood–brain barrier (BBB) remain poorly characterized. Despite great advances in recapitulating the human BBB in vitro, current models are not suitable for systematic analys
Externí odkaz:
https://doaj.org/article/0bec5e6650484393b2bce695057360c1
Autor:
Mehmet U. Girgin, Nicolas Broguiere, Sylke Hoehnel, Nathalie Brandenberg, Bastien Mercier, Alfonso Martinez Arias, Matthias P. Lutolf
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Previous approaches to derive embryoids either lack physiological morphology and signaling interactions, or are unconducive to model post-gastrulation development. Here the authors use a high-throughput approach to induce mouse embryonic stem cells i
Externí odkaz:
https://doaj.org/article/d7b6600beff74aaeac98ceb5354dc6d2
Autor:
Sonja Giger, Moritz Hofer, Marijana Miljkovic-Licina, Sylke Hoehnel, Nathalie Brandenberg, Romain Guiet, Martin Ehrbar, Esther Kleiner, Katharina Gegenschatz-Schmid, Thomas Matthes, Matthias P. Lutolf
Publikováno v:
APL Bioengineering, Vol 6, Iss 3, Pp 036101-036101-14 (2022)
In many leukemia patients, a poor prognosis is attributed either to the development of chemotherapy resistance by leukemic stem cells (LSCs) or to the inefficient engraftment of transplanted hematopoietic stem/progenitor cells (HSPCs) into the bone m
Externí odkaz:
https://doaj.org/article/ede4db85bc1f4ee29ddc191584cc3c49
Autor:
Clara Fernandez Elviro, Sylvain Blanchon, Sylke Hoehnel, Urs Schumacher, Alain Sauty, Nathalie Brandenberg, Nicolas Regamey
Publikováno v:
Swiss Medical Weekly, Vol 151, Iss 1516 (2021)
Cystic fibrosis (CF) is a genetic disease caused by a bi-allelic mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. When the diagnosis cannot be confirmed by a positive sweat test or/and the identification of two CF-caus
Externí odkaz:
https://doaj.org/article/9a31cba8737845acaa57ae083e3e1446
Autor:
Philipp S. Lienemann, Queralt Vallmajo‐Martin, Panagiota Papageorgiou, Ulrich Blache, Stéphanie Metzger, Anna‐Sofia Kiveliö, Vincent Milleret, Ana Sala, Sylke Hoehnel, Aline Roch, Raphael Reuten, Manuel Koch, Olaia Naveiras, Franz E. Weber, Wilfried Weber, Matthias P. Lutolf, Martin Ehrbar
Publikováno v:
Advanced Science, Vol 7, Iss 7, Pp n/a-n/a (2020)
Abstract The treatment of bone defects with recombinant bone morphogenetic protein‐2 (BMP‐2) requires high doses precluding broad clinical application. Here, a bioengineering approach is presented that strongly improves low‐dose BMP‐2‐based
Externí odkaz:
https://doaj.org/article/ff1b5c7bb89f4cc493ad1ee1b1a8a396
Autor:
Martina Brigitte Duschmalé, Camilla Ceroni, Hendrik Knoetgen, Sylke Hoehnel, Roberto Villaseñor, Nathalie Brandenberg, Alina Gavrilov, Jens Niewoehner, Evodie Lassalle, Claire Simonneau, Elena Kassianidou
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-17 (2021)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
Background The pathways that control protein transport across the blood–brain barrier (BBB) remain poorly characterized. Despite great advances in recapitulating the human BBB in vitro, current models are not suitable for systematic analysis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229e0f9b49e68f32bea2df88405ff107
https://doaj.org/article/0bec5e6650484393b2bce695057360c1
https://doaj.org/article/0bec5e6650484393b2bce695057360c1
Autor:
Gerald Schwank, Sylke Hoehnel, Matthias P. Lutolf, Nikolce Gjorevski, Fabien Kuttler, Camilla Ceroni, Krisztian Homicsko, Nathalie Brandenberg, Till Ringel, George Coukos, Gerardo Turcatti
Publikováno v:
Nature Biomedical Engineering. 4:863-874
Stem-cell-derived epithelial organoids are routinely used for the biological and biomedical modelling of tissues. However, the complexity, lack of standardization and quality control of stem cell culture in solid extracellular matrices hampers the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66697e737a32fb480627e764e197ac24
https://doi.org/10.1038/s41551-020-0565-2
https://doi.org/10.1038/s41551-020-0565-2
Autor:
Nathalie Brandenberg, Sylke Hoehnel, Bastien Mercier, Alfonso Martinez Arias, Mehmet Girgin, Matthias P. Lutolf, Nicolas Broguiere
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
The difficulty of studying post-implantation development in mammals has sparked a flurry of activity to develop in vitro models, termed embryoids, based on self-organizing pluripotent stem cells. Previous approaches to derive embryoids either lack th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd10b0f969535c2a451b847aeac0060e
Autor:
Sylke Hoehnel, Martin Ehrbar, Hofer M, Nathalie Brandenberg, Romain Guiet, Matthias P. Lutolf, Gegenschatz K, Sonja Giger, Miljkovic-Licina M, Thomas Matthes, Kleiner E
In many leukemia patients, a poor prognosis is attributed either to the development of chemotherapy resistance by leukemic stem cells (LSCs) or to the inefficient engraftment of transplanted hematopoietic stem/progenitor cells (HSPCs) into the bone m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ab0322925357d1009bd87ca8e5cabf
https://doi.org/10.1101/2021.05.26.445803
https://doi.org/10.1101/2021.05.26.445803
Autor:
Roberto Villaseñor, Nathalie Brandenberg, Sylke Hoehnel, Camilla Ceroni, Claire Simonneau, Martina Brigitte Duschmalé, Alina Gavrilov, Hendrik Knoetgen, Evodie Lassalle, Jens Niewoehner
BackgroundThe pathways that control protein transport across the Blood-Brain Barrier (BBB) remain poorly characterized. Despite great advances in recapitulating the human BBB in vitro, current models are not suitable for systematic analysis of the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1c0c24563e77c54d8a039fa438d2e97
https://doi.org/10.1101/2021.02.09.430382
https://doi.org/10.1101/2021.02.09.430382