Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Syed Usman Enam"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 10, p e1009813 (2021)
Translation of messenger RNAs (mRNAs) with premature termination codons produces truncated proteins with potentially deleterious effects. This is prevented by nonsense-mediated mRNA decay (NMD) of these mRNAs. NMD is triggered by ribosomes terminatin
Externí odkaz:
https://doaj.org/article/fa5279b562774fcdb51142e48baba02b
Autor:
Syed Usman Enam, Boris Zinshteyn, Daniel H Goldman, Madeline Cassani, Nathan M Livingston, Geraldine Seydoux, Rachel Green
Publikováno v:
eLife, Vol 9 (2020)
Puromycin is a tyrosyl-tRNA mimic that blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes. Puromycin has been used in molecular biology research for decades as a translation inhibitor. The developmen
Externí odkaz:
https://doaj.org/article/4f34ce7e063048d9bde53f7974f89f11
Autor:
Syed Usman Enam, Joshua L. Cherry, Susan R. Leonard, Ivan N. Zheludev, David J. Lipman, Andrew Z. Fire
Publikováno v:
Appl Environ Microbiol
Metagenomic sequencing is a swift and powerful tool to ascertain the presence of an organism of interest in a sample. However, sequencing coverage of the organism of interest can be insufficient due to an inundation of reads from irrelevant organisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6287285c01f745efd1fdb869bb36dfb
https://doi.org/10.1101/2022.09.30.510419
https://doi.org/10.1101/2022.09.30.510419
Publikováno v:
PLoS Genetics, Vol 17, Iss 10, p e1009813 (2021)
PLoS Genetics
PLoS Genetics
Translation of messenger RNAs (mRNAs) with premature termination codons produces truncated proteins with potentially deleterious effects. This is prevented by nonsense-mediated mRNA decay (NMD) of these mRNAs. NMD is triggered by ribosomes terminatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5645a0b75714b148b25c53c84d662ed3
https://doaj.org/article/fa5279b562774fcdb51142e48baba02b
https://doaj.org/article/fa5279b562774fcdb51142e48baba02b
Autor:
Geraldine Seydoux, Rachel Green, Boris Zinshteyn, Madeline Cassani, Nathan M. Livingston, Daniel Goldman, Syed Usman Enam
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Puromycin is a tyrosyl-tRNA mimic that blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes. Puromycin has been used in molecular biology research for decades as a translation inhibitor. The developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37cae74988fe2e74ec18a4a9f74ca6c
https://pubmed.ncbi.nlm.nih.gov/32844748
https://pubmed.ncbi.nlm.nih.gov/32844748
Publikováno v:
Nucleic Acids Research
Upf1 is an SF1-family RNA helicase that is essential for the nonsense-mediated decay (NMD) process in eukaryotes. While Upf1 has been shown to interact with 80S ribosomes, the molecular details of this interaction were unknown. Using purified recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73058f0dbc6ffdaa4e0a0a0384c02b1
http://europepmc.org/articles/PMC5829565
http://europepmc.org/articles/PMC5829565