Figure S1-S2 from COMMD3:BMI1 Fusion and COMMD3 Protein Regulate C-MYC Transcription: Novel Therapeutic Target for Metastatic Prostate Cancer

Autor: Mohammad Saleem, Badrinath R. Konety, Eva Corey, Colm Morrissey, Paari Murugan, Firdous H. Beigh, Raihana Maqbool, Marina G. Ferrari, Arsheed A. Ganaie, Adrian P. Mansini, Anmbreen Jamroze, Mudassir Meraj Banday, Syed Umbreen

Supplementary Data showing (i) expression of COMMD3 in PDX models and (ii) association of MYC to COMMD3 in prostate cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b8280bae0526c5a0e3ca73d5aa7376
https://doi.org/10.1158/1535-7163.22510041

figure S2 from BMI1 Drives Metastasis of Prostate Cancer in Caucasian and African-American Men and Is A Potential Therapeutic Target: Hypothesis Tested in Race-specific Models

Autor: Mohammad Saleem, Luke H. Hoeppner, Badrinath R. Konety, Yibin Deng, Shahriar Koochekpour, Colm Morrissey, Paari Murugan, Tabish Hussain, Hifzur R. Siddique, Aijaz S. Parray, Syed Umbreen, Raihana Maqbool, Marina G. Ferrari, Matteo Astone, Firdous H. Beigh, Arsheed A. Ganaie

Supplementary Figure 2. Inhibition of colony formation by BMI1 inhibitor and Docetaxel combination in African American and Caucasian CaP models on Colony-formation assay as described in material and methods.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30a006644acd083d8f05952b0771257
https://doi.org/10.1158/1078-0432.22468788

Table S1 from BMI1 Drives Metastasis of Prostate Cancer in Caucasian and African-American Men and Is A Potential Therapeutic Target: Hypothesis Tested in Race-specific Models

Autor: Mohammad Saleem, Luke H. Hoeppner, Badrinath R. Konety, Yibin Deng, Shahriar Koochekpour, Colm Morrissey, Paari Murugan, Tabish Hussain, Hifzur R. Siddique, Aijaz S. Parray, Syed Umbreen, Raihana Maqbool, Marina G. Ferrari, Matteo Astone, Firdous H. Beigh, Arsheed A. Ganaie

Supplementary Table 1. Sequence of primers used for ChIP analysis of PTEN, INK4A/p16 and GAPDH promoters.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2860bbb29e651f61cca8218c9b909234
https://doi.org/10.1158/1078-0432.22468791

BMI1 drives metastasis of prostate cancer in Caucasian and African-American men and is a potential therapeutic target: hypothesis tested in race-specific models

Autor: Aijaz Parray, Matteo Astone, Arsheed A. Ganaie, Syed Umbreen, Mohammad Saleem, Tabish Hussain, Badrinath R. Konety, Marina G. Ferrari, Shahriar Koochekpour, Colm Morrissey, Paari Murugan, Hifzur R. Siddique, Luke H. Hoeppner, Yibin Deng, Raihana Maqbool, Firdous H. Beigh

Purpose: Metastasis is the major cause of mortality in prostate cancer patients. Factors such as genetic makeup and race play critical role in the outcome of therapies. This study was conducted to investigate the relevance of BMI1 in metastatic prost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2d2cfc4e83664dae1512225cef3555
https://europepmc.org/articles/PMC6295260/

Mini-XT, a miniaturized tagmentation-based protocol for efficient sequencing of SARS-CoV-2.

Autor: Fuchs, Marc¹ (AUTHOR), Radulescu, Clara² (AUTHOR), Tang, Miao² (AUTHOR), Mahesh, Arun² (AUTHOR), Lavin, Deborah² (AUTHOR), Umbreen, Syed (AUTHOR), McKenna, James³ (AUTHOR), Smyth, Mark³ (AUTHOR), McColgan, Eilís³ (AUTHOR), Molnar, Zoltan³ (AUTHOR), Baxter, Chris¹ (AUTHOR), Skvortsov, Timofey⁴ (AUTHOR), Singh, Aditi² (AUTHOR), Rogan, Fiona² (AUTHOR), Miskelly, Julia¹ (AUTHOR), Bridgett, Stephen² (AUTHOR), Fairley, Derek³ (AUTHOR), Simpson, David A.² (AUTHOR) David.Simpson@qub.ac.uk

Publikováno v: Journal of Translational Medicine. 3/3/2022, Vol. 20 Issue 1, p1-11. 11p.