Structurally distinct telomere-binding proteins in Ustilago maydis execute non-overlapping functions in telomere replication, recombination, and protection

Autor: Eun Young Yu, Syed S. Zahid, Swapna Ganduri, Jeanette H. Sutherland, Min Hsu, William K. Holloman, Neal F. Lue

Publikováno v: Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)

Yu et al. provide evidence that Ustilago maydis employs two structurally distinct telomere-binding proteins to perform complementary functions in telomere maintenance in this organism. While UmTay1 regulates primarily telomere replication and recombi

Externí odkaz: https://doaj.org/article/c58ce736a72344009df7a09b6fe8890a

Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology

Autor: Syed S. Zahid, Xi Kathy Zhou, Eun Young Yu, Neal F. Lue, Nai-Kong V. Cheung, Sarah Aloe, Erik Falck-Pedersen

Publikováno v: Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)

Telomere maintenance and tumor cell differentiation have been separately implicated in neuroblastoma malignancy. Their mechanistic connection is unclear. We analyzed neuroblastoma cell lines and morphologic subclones representing the adrenergic (ADRN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057a4509b976c4a8bcb5d60674b1edb2
https://doi.org/10.1038/s42003-021-02821-8

Ustilago maydis telomere protein Pot1 harbors an extra N-terminal OB fold and regulates homology-directed DNA repair factors in a dichotomous and context-dependent manner

Autor: Jeanette H. Sutherland, Neal F. Lue, Syed S. Zahid, Sarah Aloe, William K. Holloman

Publikováno v: PLOS Genetics. 18:e1010182

The telomere G-strand binding protein Pot1 plays multifaceted roles in telomere maintenance and protection. We examined the structure and activities of Pot1 in Ustilago maydis, a fungal model that recapitulates key features of mammalian telomere regu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f24c7770c0fe5bf166d472dde91568
https://doi.org/10.1371/journal.pgen.1010182

Structurally distinct telomere-binding proteins in Ustilago maydis execute non-overlapping functions in telomere replication, recombination, and protection

Autor: Swapna Ganduri, Jeanette H. Sutherland, Neal F. Lue, Min Hsu, Eun Young Yu, William K. Holloman, Syed S. Zahid

Publikováno v: Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)

Duplex telomere binding proteins exhibit considerable structural and functional diversity in fungi. Herein we interrogate the activities and functions of two Myb-containing, duplex telomere repeat-binding factors in Ustilago maydis, a basidiomycete t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ad6377c6570e5e6adb9df63fcdf722
https://pubmed.ncbi.nlm.nih.gov/33328546

Potential impact of various surface ligands on the cellular uptake and biodistribution characteristics of red, green, and blue emitting Cu nanoclusters.

Autor: Busi KB; Department of Chemistry, SRM University AP Andhra Pradesh Andhra Pradesh 522240 India sabyasachi.c@srmap.edu.in., Palanivel M; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore 59 Nanyang Drive Singapore 636921 Singapore ppadmanabhan@ntu.edu.sg., Jyothi K; Department of Biological Sciences, SRM University AP Andhra Pradesh Andhra Pradesh 522240 India., LaiGuan Zoey F; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore 59 Nanyang Drive Singapore 636921 Singapore ppadmanabhan@ntu.edu.sg., Zahid S; Department of Mechanical Engineering, SRM University AP Andhra Pradesh Andhra Pradesh 522240 India., Ghosh KK; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore 59 Nanyang Drive Singapore 636921 Singapore ppadmanabhan@ntu.edu.sg.; Cognitive Neuroimaging Centre, Nanyang Technological University 59 Nanyang Drive Singapore 636921 Singapore., Agrawalla BK; Protein Chemistry 1, Roche Diagnostics GmbH Nonnenwald 2 82377 Penzberg Germany., Gulyás B; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore 59 Nanyang Drive Singapore 636921 Singapore ppadmanabhan@ntu.edu.sg.; Cognitive Neuroimaging Centre, Nanyang Technological University 59 Nanyang Drive Singapore 636921 Singapore.; Department of Clinical Neuroscience, Karolinska Institute 17176 Stockholm Sweden., Halkarni SS; Department of Mechanical Engineering, SRM University AP Andhra Pradesh Andhra Pradesh 522240 India., Thondamal M; Department of Biological Sciences, SRM University AP Andhra Pradesh Andhra Pradesh 522240 India.; Department of Biotechnology, School of Technology, Gandhi Institute of Technology and Management (GITAM) Visakhapatnam Andhra Pradesh 530045 India., Padmanabhan P; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore 59 Nanyang Drive Singapore 636921 Singapore ppadmanabhan@ntu.edu.sg.; Cognitive Neuroimaging Centre, Nanyang Technological University 59 Nanyang Drive Singapore 636921 Singapore., Chakrabortty S; Department of Chemistry, SRM University AP Andhra Pradesh Andhra Pradesh 522240 India sabyasachi.c@srmap.edu.in.

Publikováno v: RSC advances [RSC Adv] 2023 Aug 30; Vol. 13 (37), pp. 25862-25870. Date of Electronic Publication: 2023 Aug 30 (Print Publication: 2023).