Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Syed M. Faisal"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/470e6335fd3145d3bda8b959db03d9a2
Autor:
Syed M. Faisal, Jarred E. Clewner, Brooklyn Stack, Maria L. Varela, Andrea Comba, Grace Abbud, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) remains a challenge in Neuro‐oncology, with a poor prognosis showing only a 5% survival rate beyond two years. This is primarily due to its aggressiveness and intra‐tumoral heterogeneity, which limits complete surgical
Externí odkaz:
https://doaj.org/article/1538c238cfc34c618bb0253cf99982f3
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira spp. having more than 300 serovars. These serovars can infect a variety of hosts, some being asymptomatic carriers and others showing varied symptoms of mild to severe infection. S
Externí odkaz:
https://doaj.org/article/bb0234b6dd4046e781c94a73f8580f76
Autor:
Andrea Comba, Maria Luisa Varela, Syed M. Faisal, Clifford C. Abel, II, Anna E. Argento, Wajd N. Al-Holou, Todd C. Hollon, Jacqueline D. Perelman, Patrick J. Dunn, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102174- (2023)
Summary: Development of spatial-integrative pre-clinical models is needed for glioblastoma, which are heterogenous tumors with poor prognosis. Here, we present an optimized protocol to generate three-dimensional ex vivo explant slice glioma model fro
Externí odkaz:
https://doaj.org/article/2c43e2be55634ce0ab0275ab171a6f0b
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1824 (2023)
Leptospirosis is a globally significant zoonotic disease. The current inactivated vaccine offers protection against specific serovars but does not provide complete immunity. Various surface antigens, such as Leptospira immunoglobulin-like proteins (L
Externí odkaz:
https://doaj.org/article/b7ab8bd53b3d4acf90196fdcd1bf1de7
Autor:
Andrea Comba, Syed M. Faisal, Patrick J. Dunn, Anna E. Argento, Todd C. Hollon, Wajd N. Al-Holou, Maria Luisa Varela, Daniel B. Zamler, Gunnar L. Quass, Pierre F. Apostolides, Clifford Abel, Christine E. Brown, Phillip E. Kish, Alon Kahana, Celina G. Kleer, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
It is essential to improve our understanding of the features that influence aggressiveness and invasion in high grade gliomas (HGG). Here, the authors characterize dynamic anatomical structures in HGG called oncostreams, which are associated with tum
Externí odkaz:
https://doaj.org/article/3b351a9de1174a41bae1168e3664c972
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Leptospirosis is a zoonotic disease of global importance. The current vaccine provides serovar-specific and short-term immunity and does not prevent bacterial shedding in infected animals. Subunit vaccines based on surface proteins have shown to indu
Externí odkaz:
https://doaj.org/article/0ab1a7da882041ffb0641d11d65eae73
Autor:
Syed M. Faisal, Andrea Comba, Maria L. Varela, Anna E. Argento, Emily Brumley, Clifford Abel, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastoma (GBM), an aggressive high-grade glial tumor, is resistant to therapy and has a poor prognosis due to its universal recurrence rate. GBM cells interact with the non-cellular components in the tumor microenvironment (TME), facilitating the
Externí odkaz:
https://doaj.org/article/ab3ac9d856fb4768a00c709bfdd97349
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Leptospira, a zoonotic pathogen, is capable of causing both chronic and acute infection in a susceptible host. Surface-exposed lipoproteins play a major role in modulating the host immune response by activating the innate cells like macrophages and d
Externí odkaz:
https://doaj.org/article/0e6c1fd61a974e3bb0ef8976a07d8d92
Autor:
Ajay Kumar, Vivek P. Varma, Kavela Sridhar, Mohd Abdullah, Pallavi Vyas, Muhammed Ashiq Thalappil, Yung-Fu Chang, Syed M. Faisal
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Leptospira, a zoonotic pathogen, is known to infect various hosts and can establish persistent infection. This remarkable ability of bacteria is attributed to its potential to modulate (activate or evade) the host immune response by exploiting its su
Externí odkaz:
https://doaj.org/article/8041059ea0dc431b87df186d722fc8c9