Výsledky vyhledávání - "Syed Akbar Zulquernain"

Making computed tomography safer for patients with Crohn’s disease

Autor: Syed Akbar Zulquernain, Aislinn O'Connell, Richard G. Kavanagh, Owen J. O'Connor, John O’Grady, Michael M. Maher, Brian W. Carey, Fergus Shanahan, Elizabeth Kenny-Walsh

Publikováno v: Scandinavian Journal of Gastroenterology. 57:175-182

Background and aims: Computed tomography (CT), often more accessible than magnetic resonance imaging (MRI), remains widely used though radiation exposure is an obvious disadvantage. We previously showed that modern CT technology can achieve over 70%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd510efc3a9b52175e02a3d43d599bfe
https://doi.org/10.1080/00365521.2021.1994640

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Human BCL-G regulates secretion of inflammatory chemokines but is dispensable for induction of apoptosis by IFN-γ and TNF-α in intestinal epithelial cells

Autor: Silvia Melgar, Syed Akbar Zulquernain, Kenneth Nally, Gerry Moloney, Aine Fanning, Milan Bustamante-Garrido, Peter Flood, Fergus Shanahan, Jerzy A. Woznicki, Panagiota Stamou, Jane McCarthy

Publikováno v: Cell Death and Disease, Vol 11, Iss 1, Pp 1-15 (2020)
Cell Death & Disease

Proteins of the BCL-2 family are evolutionarily conserved modulators of apoptosis that function as sensors of cellular integrity. Over the past three decades multiple BCL-2 family members have been identified, many of which are now fully incorporated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe4bd04c072d4fc69df019f80d14872
http://link.springer.com/article/10.1038/s41419-020-2263-0

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TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

Autor: Subhasree Rajaram, Simon S. McDade, Daniel B. Longley, Panagiota Stamou, Pedro Aza-Blanc, Ciaran M. Lee, Jerzy A. Woznicki, Karine Regazzoni, Nisha Saini, Nyree Crawford, Kenneth Nally, Fergus Shanahan, Jane McCarthy, Agnieszka Skowyra, Syed Akbar Zulquernain, Milan Bustamante-Garrido, Bradford L McRae, Silvia Melgar, Peter Flood

Publikováno v: Woznicki, J A, Saini, N, Flood, P, Rajaram, S, Lee, C M, Stamou, P, Skowyra, A, Bustamante-Garrido, M, Regazzoni, K, Crawford, N, McDade, S S, Longley, D B, Aza-Blanc, P, Shanahan, F, Zulquernain, S A, McCarthy, J, Melgar, S, McRae, B L & Nally, K 2021, ' TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells ', Cell, Death & Disease, vol. 12, 864 . https://doi.org/10.1038/s41419-021-04151-3
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-15 (2021)

Rewiring of host cytokine networks is a key feature of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD). Th1-type cytokines—IFN-γ and TNF-α—occupy critical nodes within these networks and both are associated with disruption of g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924890d99a776d6334e0fc589b423a46
https://pure.qub.ac.uk/en/publications/14c63377-1829-45d8-812f-a5990eae4915

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Colorectal microbiota after removal of colorectal cancer

Autor: Peter Cronin, Clodagh L Murphy, Maurice Barrett, Tarini Shankar Ghosh, Paola Pellanda, Eibhlis M O’Connor, Syed Akbar Zulquernain, Shane Kileen, Morgan McCourt, Emmet Andrews, Micheal G O’Riordain, Fergus Shanahan, Paul W O’Toole

Publikováno v: NAR cancer. 4(2)

The colonic microbiome has been implicated in the pathogenesis of colorectal cancer (CRC) and intestinal microbiome alterations are not confined to the tumour. Since data on whether the microbiome normalises or remains altered after resection of CRC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5e216849b6e5a0469d08e77fcf2f8f
https://pubmed.ncbi.nlm.nih.gov/35399186

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