Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sydonia Rayter"'
Autor:
Jorge S. Reis-Filho, Alan Ashworth, Horst Buerger, Christopher J. Lord, Jose Palacios, Andrew Tutt, David Hardisson, Narinder Tamber, Kerry Fenwick, Anita Grigoriadis, Alan Mackay, Daniela Hungermann, Laura G. Fulford, Betania Mahler-Araujo, Sydonia Rayter, Radost Vatcheva, Caterina Marchió, David S.P. Tan, Gema Moreno-Bueno, Socorro María Rodríguez-Pinilla, Maryou B. Lambros, Rachael Natrajan
Supplementary Data from Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48a470e0bd4590c5264245a873108d8
https://doi.org/10.1158/1078-0432.22440147
https://doi.org/10.1158/1078-0432.22440147
Autor:
Jorge S. Reis-Filho, Alan Ashworth, Stanley B. Kaye, Christopher J. Lord, Marketa Zvelebil, Martin E. Gore, Hani Gabra, Adam J. Paige, Mona El-Bahrawy, Dana Faratian, Ashley Graham, Alistair Williams, W. Glenn McCluggage, Charles Jameson, Tim Dexter, Alan Mackay, Narinder Tamber, Kerry Fenwick, Suzanne Parry, Kay Savage, Felipe C. Geyer, Caterina Marchiò, Qiong Gao, Radost Vatcheva, Rachael Natrajan, Sydonia Rayter, Maryou B.K. Lambros, David S.P. Tan
Purpose: To identify therapeutic targets in ovarian clear cell carcinomas, a chemoresistant and aggressive type of ovarian cancer.Experimental Design: Twelve ovarian clear cell carcinoma cell lines were subjected to tiling path microarray comparative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6300175e42417bb29f81a0aa29f88c95
https://doi.org/10.1158/1078-0432.c.6517677.v1
https://doi.org/10.1158/1078-0432.c.6517677.v1
Autor:
Jorge S. Reis-Filho, Alan Ashworth, Stanley B. Kaye, Christopher J. Lord, Marketa Zvelebil, Martin E. Gore, Hani Gabra, Adam J. Paige, Mona El-Bahrawy, Dana Faratian, Ashley Graham, Alistair Williams, W. Glenn McCluggage, Charles Jameson, Tim Dexter, Alan Mackay, Narinder Tamber, Kerry Fenwick, Suzanne Parry, Kay Savage, Felipe C. Geyer, Caterina Marchiò, Qiong Gao, Radost Vatcheva, Rachael Natrajan, Sydonia Rayter, Maryou B.K. Lambros, David S.P. Tan
Supplementary Data from PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7afcff53316beec302b82a99acd1ad
https://doi.org/10.1158/1078-0432.22440333.v1
https://doi.org/10.1158/1078-0432.22440333.v1
Autor:
Jorge S. Reis-Filho, Alan Ashworth, Horst Buerger, Christopher J. Lord, Jose Palacios, Andrew Tutt, David Hardisson, Narinder Tamber, Kerry Fenwick, Anita Grigoriadis, Alan Mackay, Daniela Hungermann, Laura G. Fulford, Betania Mahler-Araujo, Sydonia Rayter, Radost Vatcheva, Caterina Marchió, David S.P. Tan, Gema Moreno-Bueno, Socorro María Rodríguez-Pinilla, Maryou B. Lambros, Rachael Natrajan
Purpose: To characterize the molecular genetic profiles of grade 3 invasive ductal carcinomas of no special type using high-resolution microarray-based comparative genomic hybridization (aCGH) and to identify recurrent amplicons harboring putative th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c089d7052eeb0c87d27e5c1d1af17029
https://doi.org/10.1158/1078-0432.c.6517515.v1
https://doi.org/10.1158/1078-0432.c.6517515.v1
Autor:
J. Travers, Keith Jones, Paul Workman, Martin G. Rowlands, Wynne Aherne, Christopher J. Lord, Spyridon Linardopoulos, Richard Elliott, Sydonia Rayter, K. Boxall, T. B. Richardson, Alan Ashworth
Publikováno v:
Oncogene. 39:4780-4780
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8088f244226aefdfa3e3e886ad8e9cec
https://doi.org/10.1038/s41388-020-1309-1
https://doi.org/10.1038/s41388-020-1309-1
Autor:
David S.P. Tan, Martin Gore, Marketa Zvelebil, Suzanne Parry, Alan Mackay, Tim Dexter, Qiong Gao, Dana Faratian, Alan Ashworth, Sydonia Rayter, Adam J.W. Paige, Hani Gabra, Caterina Marchiò, Maryou B K Lambros, Mona El-Bahrawy, Felipe C. Geyer, Alistair R.W. Williams, Kay Savage, Christopher J. Lord, Narinder Tamber, Stanley B. Kaye, Charles Jameson, W. Glenn McCluggage, Radost Vatcheva, Rachael Natrajan, Ashley D. Graham, Jorge S. Reis-Filho, Kerry Fenwick
Publikováno v:
Clinical Cancer Research. 15:2269-2280
Purpose: To identify therapeutic targets in ovarian clear cell carcinomas, a chemoresistant and aggressive type of ovarian cancer. Experimental Design: Twelve ovarian clear cell carcinoma cell lines were subjected to tiling path microarray comparativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4196b794238b6910f95445d50d9f9724
https://doi.org/10.1158/1078-0432.ccr-08-2403
https://doi.org/10.1158/1078-0432.ccr-08-2403
Autor:
Christopher J. Lord, Spiros Linardopoulos, J. Travers, Wynne Aherne, T. B. Richardson, Keith Jones, Paul Workman, Richard Elliott, K. Boxall, Alan Ashworth, Sydonia Rayter, Martin G. Rowlands
Publikováno v:
Oncogene. 27:1036-1044
The PPM1D gene is aberrantly amplified in a range of common cancers and encodes a protein phosphatase that is a potential therapeutic target. However, the issue of whether inhibition of PPM1D in human tumour cells that overexpress this protein compro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ffc5538ac0327bb4764e2e38c60b83
https://doi.org/10.1038/sj.onc.1210729
https://doi.org/10.1038/sj.onc.1210729
Autor:
Spiros Linardopoulos, Rosemary Burke, Amir Faisal, Maura Westlake, Michael Swan, Matthew D. Cheeseman, Sydonia Rayter, Andrew Kalusa, Olivier Barbeau, Keith Jones, Rob L. M. van Montfort
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(15)
The metal-dependent phosphatase PPM1D (WIP1) is an important oncogene in cancer, with over-expression of the protein being associated with significantly worse clinical outcomes. In this communication we describe the discovery and optimization of nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5263f8cc7e64b6e084259fc52b63fc53
https://pubmed.ncbi.nlm.nih.gov/24953599
https://pubmed.ncbi.nlm.nih.gov/24953599
Autor:
Andrew Tutt, José Palacios, Narinder Tamber, Alan Mackay, Jorge S. Reis-Filho, David Hardisson, Betania Mahler-Araujo, Maryou B K Lambros, Anita Grigoriadis, Horst Buerger, Sydonia Rayter, D. Hungermann, Radost Vatcheva, Rachael Natrajan, Christopher J. Lord, L G Fulford, David S.P. Tan, Alan Ashworth, Kerry Fenwick, Caterina Marchiò, Gema Moreno-Bueno, Socorro María Rodríguez-Pinilla
Purpose: To characterize the molecular genetic profiles of grade 3 invasive ductal carcinomas of no special type using high-resolution microarray-based comparative genomic hybridization (aCGH) and to identify recurrent amplicons harboring putative th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1a976ea5f3e7d1af031204b630512d
http://hdl.handle.net/2318/64038
http://hdl.handle.net/2318/64038
Autor:
Alan Ashworth, Elizabeth Iorns, Richard Elliott, Andrew Tutt, Nicholas C. Turner, Sydonia Rayter, Christopher J. Lord, Rachel Brough, Sally Swift
Inhibitors of poly (ADP-ribose)-polymerase-1 (PARP) are highly lethal to cells with deficiencies in BRCA1, BRCA2 or other components of the homologous recombination pathway. This has led to PARP inhibitors entering clinical trials as a potential ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d009e212a1f977cbfe3539917c17257
https://europepmc.org/articles/PMC2374839/
https://europepmc.org/articles/PMC2374839/