Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sydni M. Bellow"'
Autor:
Sydni M. Bellow, Xiaoyi Zhang, Maryam Foroozesh, Patrick S. Dupart, Jayalakshmi Sridhar, Lydia M. Mensah, Ming Zhao, Jiawang Liu, Erika McClain, Shannon Taylor, La’nese J. Lovings, Navneet Goyal, Brandan Dotson
Publikováno v:
Chemical Research in Toxicology
The flavone backbone is a well-known pharmacophore present in a number of substrates and inhibitors of various P450 enzymes. In order to find highly potent and novel P450 family I enzyme inhibitors, an acetylene group was incorporated into six differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12db5c0a0b92120b311536350cd4eed
https://doi.org/10.1021/tx5001865
https://doi.org/10.1021/tx5001865
Autor:
Ming Zhao, Lydia M. Mensah, Elena Skripnikova, Peter T. Pham, Yuji Wang, Sydni M. Bellow, La’nese J. Lovings, Maryam Foroozesh, Amari J. Chatters, Jiawang Liu, Thomas E. Wiese, Shilong Zheng, Guangdi Wang, Navneet Goyal, Melyssa R. Bratton
Publikováno v:
Journal of medicinal chemistry. 58(16)
In humans, cytochrome P450 1A2 is the major enzyme metabolizing environmental arylamines or heterocyclic amines into carcinogens. Since evidence shows that planar triangle-shaped molecules are capable of selectively inhibiting P450 1A2, 16 triangular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de40ad2ad0c5c1e674cc88d663ece9b4
https://pubmed.ncbi.nlm.nih.gov/26222195
https://pubmed.ncbi.nlm.nih.gov/26222195
Autor:
Jiawang Liu, PeterT. Pham, Elena V. Skripnikova, Shilong Zheng, La’neseJ. Lovings, Yuji Wang, Navneet Goyal, Sydni M. Bellow, Lydia M. Mensah, Amari J. Chatters, Melyssa R. Bratton, Thomas E. Wiese, Ming Zhao, Guangdi Wang, Maryam Foroozesh
Publikováno v:
Journal of Medicinal Chemistry; Aug2015, Vol. 58 Issue 16, p6481-6493, 13p