Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sydney Treichel"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Hematopoietic stem cells (HSCs) have the properties to self-renew and/or differentiate into any blood cell lineages. In order to balance the maintenance of the stem cell pool with supporting mature blood cell production, the fate decisions to self-re
Externí odkaz:
https://doaj.org/article/1e1bf575f4de4eeabd6e850300928b27
Autor:
Allegra G. Hawkins, Claire M. Julian, Sonja Konzen, Sydney Treichel, Elizabeth R. Lawlor, Kelly M. Bailey
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 10, Pp 1063-1072 (2019)
Ewing sarcoma is a bone tumor most commonly diagnosed in adolescents and young adults. Survival for patients with recurrent or metastatic Ewing sarcoma is dismal and there is a dire need to better understand the mechanisms of cell metastasis specific
Externí odkaz:
https://doaj.org/article/df1cad9c71c6453ba765790c2becb9ca
Autor:
Kelly M. Bailey, Elizabeth R. Lawlor, Sonja Marie Konzen, Sydney Treichel, Claire M. Julian, Allegra G. Hawkins
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 10, Pp 1063-1072 (2019)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 10, Pp 1063-1072 (2019)
Ewing sarcoma is a bone tumor most commonly diagnosed in adolescents and young adults. Survival for patients with recurrent or metastatic Ewing sarcoma is dismal and there is a dire need to better understand the mechanisms of cell metastasis specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4136ee0b1e8dd1e5e12eff4e8da8e241
https://doi.org/10.1016/j.neo.2019.08.007
https://doi.org/10.1016/j.neo.2019.08.007
Autor:
Jay Read, Kelsey Temprine, Elizabeth R. Lawlor, Rashmi Chugh, Sydney Treichel, Elisabeth A. Pedersen, Colin Sperring, Brian Magnuson, Allegra G. Hawkins
Publikováno v:
JCI Insight
Wnt/β-catenin signaling is active in small subpopulations of Ewing sarcoma cells, and these cells display a more metastatic phenotype, in part due to antagonism of EWS-FLI1-dependent transcriptional activity. Importantly, these β-catenin-activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18429c7da5ba378687363c1468785724
https://europepmc.org/articles/PMC7406270/
https://europepmc.org/articles/PMC7406270/
Autor:
Christopher J. Halbrook, Li Zhang, Daniel M. Kremer, Elizabeth R. Lawlor, Ho-Joon Lee, Costas A. Lyssiotis, Sudha Sud, Armand Bankhead, Szymon Klossowski, Selina Shiqing K. Teh, Dafydd G. Thomas, Laurie K. Svoboda, Aaron Zebolsky, Sydney Treichel, Tomasz Cierpicki, Mats Ljungman, Brian Magnuson, Samuel A. Kerk, Jolanta Grembecka
Publikováno v:
The Journal of Pathology. 245:324-336
Developmental transcription programs are epigenetically regulated by multi-protein complexes, including the menin- and MLL-containing trithorax (TrxG) complexes, which promote gene transcription by depositing the H3K4me3 activating mark at target gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4111a13821d373f0cb151a66380bd2cc
https://doi.org/10.1002/path.5085
https://doi.org/10.1002/path.5085
Autor:
Tahra K. Suhan, Parker K. Acevedo, Laurie K. McCauley, Allegra G. Hawkins, Wei Jiang, Elizabeth R. Lawlor, Kurt D. Hankenson, Amy J. Koh, Kelsey Temprine, Sydney Treichel
Publikováno v:
Cancer Research. 80:B74-B74
Background: Ewing sarcoma is the second most common pediatric bone cancer. Metastatic disease is almost always fatal, and there is currently no method to predict which patients are at risk for metastasis. Better therapies are needed to prevent and tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4c1665b6c8933135e5eec216b59934
https://doi.org/10.1158/1538-7445.pedca19-b74
https://doi.org/10.1158/1538-7445.pedca19-b74
Autor:
Laurie K, Svoboda, Selina Shiqing K, Teh, Sudha, Sud, Samuel, Kerk, Aaron, Zebolsky, Sydney, Treichel, Dafydd, Thomas, Christopher J, Halbrook, Ho-Joon, Lee, Daniel, Kremer, Li, Zhang, Szymon, Klossowski, Armand R, Bankhead, Brian, Magnuson, Mats, Ljungman, Tomasz, Cierpicki, Jolanta, Grembecka, Costas A, Lyssiotis, Elizabeth R, Lawlor
Publikováno v:
The Journal of pathology. 245(3)
Developmental transcription programs are epigenetically regulated by multi-protein complexes, including the menin- and MLL-containing trithorax (TrxG) complexes, which promote gene transcription by depositing the H3K4me3 activating mark at target gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b16b149d709631c4fa96a4b2544dd07
https://pubmed.ncbi.nlm.nih.gov/29672864
https://pubmed.ncbi.nlm.nih.gov/29672864
Abstract 3645: Cooperation between canonical Wnt and TGF-beta pathways promotes sarcoma angiogenesis
Autor:
Allegra G. Hawkins, Elisabeth A. Pedersen, Wei Jiang, Sydney Treichel, Colin Sperring, Jay Read, Brian Magnuson, Rajiv M. Patel, Dafydd Thomas, Rashmi Chugh, Elizabeth R. Lawlor
Publikováno v:
Cancer Research. 79:3645-3645
Local and metastatic progression of solid tumors depends on crosstalk between tumor cells and the tumor microenvironment (TME), including both stromal cells and the extracellular matrix (ECM). We recently showed that high Wnt/beta-catenin activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3767fb54ea6eaed1156c92ce606cfc
https://doi.org/10.1158/1538-7445.am2019-3645
https://doi.org/10.1158/1538-7445.am2019-3645