Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sydney Simpson"'
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011912 (2024)
BST2/Tetherin is a restriction factor with broad antiviral activity against enveloped viruses, including coronaviruses. Specifically, BST2 traps nascent particles to membrane compartments, preventing their release and spread. In turn, viruses have ev
Externí odkaz:
https://doaj.org/article/83051c964171495d9928e38f6b8cd636
Autor:
Yuhang Shi, Sydney Simpson, Shahad K. Ahmed, Yuexuan Chen, Aidin Tavakoli-Tameh, Sanath Kumar Janaka, David T. Evans, Ruth Serra-Moreno
Publikováno v:
Viruses, Vol 15, Iss 9, p 1961 (2023)
SERINC5 is a restriction factor that becomes incorporated into nascent retroviral particles, impairing their ability to infect target cells. In turn, retroviruses have evolved countermeasures against SERINC5. For instance, the primate lentiviruses (H
Externí odkaz:
https://doaj.org/article/ccf1b56013d248aab59ac4d09bc9ccde
Autor:
Muhammad Uzar Ali, Bhupesh Kumar Mishra, Dhavalkumar Thakker, Suvodeep Mazumdar, Sydney Simpson
Publikováno v:
IoT, Vol 2, Iss 2, Pp 275-309 (2021)
A key aspect of the development of Smart Cities involves the efficient and effective management of resources to improve liveability. Achieving this requires large volumes of sensors strategically deployed across urban areas. In many cases, however, i
Externí odkaz:
https://doaj.org/article/0191390f2c574bb08da08176a4ba8e22
Autor:
Sergio Castro-Gonzalez, Sydney Simpson, Yuhang Shi, Yuexuan Chen, Jared Benjamin, Ruth Serra-Moreno
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Ubiquitination is a process that acts upon every step of the HIV replication cycle. The activity, subcellular localization, and stability of HIV dependency factors as well as negative modulators can be affected by ubiquitination. These modifications
Externí odkaz:
https://doaj.org/article/7c5c9d6434424a1f873682eafc841d95
Autor:
Rameez Raja Kureshi, Bhupesh Kumar Mishra, Dhavalkumar Thakker, Reena John, Adrian Walker, Sydney Simpson, Neel Thakkar, Agot Kirsten Wante
Publikováno v:
Sensors, Vol 22, Iss 3, p 1093 (2022)
With the emergence of Low-Cost Sensor (LCS) devices, measuring real-time data on a large scale has become a feasible alternative approach to more costly devices. Over the years, sensor technologies have evolved which has provided the opportunity to h
Externí odkaz:
https://doaj.org/article/08dac04892a2401c89c135066aba96b2
Autor:
Sydney Simpson, Guillaume Fiches, Maxime J. Jean, Michael Dieringer, James McGuinness, Sinu P. John, Meir Shamay, Prashant Desai, Jian Zhu, Netty G. Santoso
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic virus responsible for the development of Kaposi’s sarcoma, primary effusion lymphoma (PEL), and Multicentric Castleman’s disease in immunocompromised individuals. Despite the burden
Externí odkaz:
https://doaj.org/article/7233ed0a1945489f856f6b9c67d0a0b5
Autor:
Maxime J. Jean, Tsuyoshi Hayashi, Huachao Huang, Justin Brennan, Sydney Simpson, Andrei Purmal, Katerina Gurova, Michael C. Keefer, James J. Kobie, Netty G. Santoso, Jian Zhu
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Despite combination antiretroviral therapy (cART), acquired immunodeficiency syndrome (AIDS), predominantly caused by the human immunodeficiency virus type 1 (HIV-1), remains incurable. The barrier to a cure lies in the virus' ability to establish a
Externí odkaz:
https://doaj.org/article/0186659eae02410ab9fa01aa141857c2
Autor:
Huachao Huang, Shuai Liu, Maxime Jean, Sydney Simpson, He Huang, Mark Merkley, Tsuyoshi Hayashi, Weili Kong, Irene Rodríguez-Sánchez, Xiaofeng Zhang, Hailemichael O. Yosief, Hongyu Miao, Jianwen Que, James J. Kobie, James Bradner, Netty G. Santoso, Wei Zhang, Jian Zhu
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
While combinatory antiretroviral therapy (cART) can effectively reduce HIV-1 viremia, it cannot eliminate HIV-1 infection. In the presence of cART, viral reservoirs remain latent, impeding the cure of HIV-1/AIDS. Recently, latency-reversing agents (L
Externí odkaz:
https://doaj.org/article/df67256a4ff2483891fd42f61b54032d
Autor:
Cindy K. Sotelo, Sarah B. Shropshire, Jessica Quimby, Sydney Simpson, Daniel L. Gustafson, Kristin M. Zersen
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 45:508-515
The purpose of this study was to evaluate the pharmacokinetics of intravenous (IV) ondansetron in a population of hospitalized dogs exhibiting clinical signs of nausea. The causes of nausea included pancreatitis, gastroenteritis, endocarditis, chemot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8974cfe62237c22f5e13fbf837107070
https://doi.org/10.1111/jvp.13087
https://doi.org/10.1111/jvp.13087
Autor:
Sydney Simpson, Chelsey McMinn, Sherry M. Van Mondfrans, Jackson Hendry, Sean Ronayne, Stephen Dewhurst, Changyong Feng, B. Sonny Bal, Ryan M. Bock, Bryan J. McEntire
Publikováno v:
Biomedical Materials & Devices.
Medical-grade masks and N95 respirators containing non-woven fibers are designed to prevent the spread of airborne diseases. While they effectively trap respiratory droplets and aerosols, they cannot lyse entrapped pathogens. Embedded antimicrobial a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::831660046dea22d031c99c66966dfc99
https://doi.org/10.1007/s44174-022-00001-8
https://doi.org/10.1007/s44174-022-00001-8